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Postdoc Single Cell Rna Sequencing Analysis Jobs in Ohio

Bioinformaticist

Columbus, OH · On-site

$86K - $123K/yr

... sequencing, ATAC-seq, miRNA-seq, RNA-seq, and ChIP-Seq bioinformatic workflows. * Working with high throughput scRNA-Seq, scATAC-Seq analysis using existing single cell analysis software like Seurat ...

Bioinformaticist

Columbus, OH · On-site

$86K - $123K/yr

... sequencing, ATAC-seq, miRNA-seq, RNA-seq, and ChIP-Seq bioinformatic workflows. * Working with high throughput scRNA-Seq, scATAC-Seq analysis using existing single cell analysis software like Seurat ...

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Postdoc Single Cell Rna Sequencing Analysis information

What is the difference between Postdoc Single Cell Rna Sequencing Analysis vs Postdoc Bioinformatics?

AspectPostdoc Single Cell Rna Sequencing AnalysisPostdoc Bioinformatics
Required CredentialsPhD in Biology, Genetics, or related field; experience in sequencing data analysisPhD in Computer Science, Bioinformatics, or related field; programming skills essential
Work EnvironmentResearch labs focusing on genomics and cell biologyResearch institutions, biotech companies, or academic labs with computational focus
Employer & Industry UsageBiotech, academic research, pharmaceutical companiesBiotech, healthcare, academic research, industry R&D

Postdoc Single Cell Rna Sequencing Analysis specialists focus on analyzing single-cell transcriptomics data, often requiring biological expertise and lab experience. In contrast, Postdoc Bioinformatics roles emphasize computational skills and software development to interpret large datasets across various biological contexts. Both roles are vital in genomics research but differ in their primary focus and skill set.

What are the key skills and qualifications needed to thrive as a postdoc in single cell RNA sequencing analysis, and why are they important?

To thrive as a Postdoc in Single Cell RNA Sequencing Analysis, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by a PhD in a relevant field. Proficiency with computational tools such as R, Python, and specialized single-cell analysis platforms (e.g., Seurat, Scanpy), as well as experience with data visualization and next-generation sequencing, is essential. Strong problem-solving abilities, effective communication, and collaboration skills help distinguish top candidates in interdisciplinary research environments. These skills enable accurate data interpretation, drive innovation, and support impactful scientific discoveries in complex biological systems.

What are some common challenges faced by postdocs working in single cell RNA sequencing analysis, and how can they be addressed?

Postdocs in single cell RNA sequencing analysis often encounter challenges such as managing large and complex datasets, integrating multi-omic data, and staying current with rapidly evolving bioinformatics tools. Collaborating closely with wet lab scientists and computational biologists is essential to interpret results accurately and to troubleshoot technical issues. Building strong programming and statistical skills, as well as actively participating in lab meetings and seminars, can help address these challenges and contribute to both personal growth and successful project outcomes.

What does a postdoc in single cell RNA sequencing analysis do?

A Postdoc in Single Cell RNA Sequencing (scRNA-seq) Analysis specializes in analyzing gene expression data from individual cells. Their main responsibilities include processing raw sequencing data, performing quality control, identifying cell types or states, and interpreting biological insights from the data. They often develop or apply computational methods to handle large datasets, collaborate with experimental biologists, and present findings through publications or conferences. The ultimate goal is to understand cellular heterogeneity and uncover new biological mechanisms at the single-cell level.

Postdoctoral Fellow - Heart Development and Regeneration Lab

Nationwide Children's Hospital

Columbus, OH • On-site

$45K - $62K/yr

Other

This job post has expired 2 days ago. Applications are no longer accepted.


Nationwide Children's Hospital rating

6.9

Company rating: 6.9 out of 10

Based on 131 frontline employees who took The Breakroom Quiz

551st of 1,055 rated hospitals


Job description

Dr. Deqiang Li's Lab


A fulltime postdoctoral position is immediately available in Dr. Deqiang Li’s Laboratory, in the Center for Cardiovascular Research at the Nationwide Children’s Hospital (NCH) Research Institute, Ohio State University. This position is supported by a NIH-R01 grant. Research in my laboratory is focused on understanding the mechanisms of cardiovascular development, disease, and regeneration. For more details, please visit our lab website: https://www.nationwidechildrens.org/research/areas-of-research/center-for-cardiovascular-research/li-lab and read our recent paper on Circ Res, 2022 (PMID: 35722872), Nature Communications, 2024 (PMID: 38755146), and Circulation, 2025 (PMID: 38755146).


In particular, we are interested in identifying the novel signaling pathways that regulate myocardial development or govern cardiomyocyte differentiation and maturation by using in vitro and in vivo approaches. Note: the PI strongly supports trainee career development. For instance, his first postdoc recruited in 2018 successfully was awarded an American Heart Association Career Development Award in 2023, and a NIH-R01 grant in 2025. She already started her own independent lab in 2025.


About the Role


Cell and mouse model systems, including induced pluripotent stem cells (iPSCs) and conditional gene knockouts will be used in these research projects. Many state-of-the-art techniques are employed, such as CRISPR/Cas9 Genome Editing, AAV, single cell RNA-Seq and ChIP Seq, confocal microscopy, multicolor flow and sorting, surgical models, ultrasonic and telemetric measurements of cardiovascular function in mice.


Responsibilities


  • Conduct research using cell and mouse model systems.
  • Utilize state-of-the-art techniques such as CRISPR/Cas9 Genome Editing, AAV, single cell RNA-Seq and ChIP Seq.
  • Perform confocal microscopy, multicolor flow and sorting, and surgical models.
  • Measure cardiovascular function in mice using ultrasonic and telemetric methods.


Qualifications


  • Applicants must have a PhD, MD or equivalent degree within last 3 years.


Required Skills


  • Proven skills and experience in molecular biology.
  • Experience in mouse genetics or generation of cardiac surgical models in mice.
  • Good writing and oral communication skills in English.
  • Ability to work both independently and collaboratively.
  • Background and experience in developmental biology using mouse models.
  • Experience with iPSCs or generation of cardiac surgical mouse models.



Interested candidates should send your CV and contact information for three references. Please send your application to deqiang.li@nationwidechildrens.org Review of applications will continue until the position is filled.



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About Nationwide Children's Hospital

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Nationwide Children's Hospital, established in 1894, is a leading pediatric healthcare system based in Columbus, Ohio, United States. They serve as a primary pediatric network, providing wellness, preventive, diagnostic, treatment, and rehabilitative care for infants, children, adolescents, and adults with congenital disease. Being the third-largest pediatric hospital in the nation, Nationwide Children's Hospital prides itself on its relentless commitment to children and their families, driven by their core values of respect, integrity, determination, empathy, and solidarity. The institution's comprehensive mission is to enhance the health of children by providing high-quality, family-centered care, conducting groundbreaking research, advocating for pediatric health, and training top healthcare professionals.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Columbus, OH, US

Year founded

1892