Contribute to the setup and organization of the Client's vector process development capabilities ... End-to-end experience in plasmid and Lentivirus development and manufacturing Experience with high ...
Contribute to the setup and organization of the Client's vector process development capabilities ... End-to-end experience in plasmid and Lentivirus development and manufacturing Experience with high ...
Sr. Manager, Quality Operations
$110K - $150K/yr
Demonstrated knowledge of biologics, viral vector, and plasmid manufacturing and testing. The Pay range is estimated between $110000 - $150000, based on experience and skill set # LW # PB Benefits:
Quick apply
Sr. Manager, Quality Operations
$110K - $150K/yr
Demonstrated knowledge of biologics, viral vector, and plasmid manufacturing and testing. The Pay range is estimated between $110000 - $150000, based on experience and skill set # LW # PB Benefits:
Contribute to the setup and organization of the Client's vector process development capabilities ... End-to-end experience in plasmid and Lentivirus development and manufacturing * Experience with ...
Contribute to the setup and organization of the Client's vector process development capabilities ... End-to-end experience in plasmid and Lentivirus development and manufacturing * Experience with ...
Senior Scientist, Viral Upstream Process Development (Philadelphia, PA)
Philadelphia, PA · On-site
$92K - $126K/yr
Contribute to the setup and organization of the Client's vector process development capabilities ... End-to-end experience in plasmid and Lentivirus development and manufacturing * Experience with ...
Senior Scientist, Viral Upstream Process Development (Philadelphia, PA)
Philadelphia, PA · On-site
$92K - $126K/yr
Contribute to the setup and organization of the Client's vector process development capabilities ... End-to-end experience in plasmid and Lentivirus development and manufacturing * Experience with ...
Associate Scientist II, Bioassays
$70K - $80K/yr
... plasmid cloning, AAV packaging, protein expression vectors, microbiology including bacterial cultures and autoclaving, cell culture including transfections and cell line maintenance * Prior ...
Associate Scientist II, Bioassays
$70K - $80K/yr
... plasmid cloning, AAV packaging, protein expression vectors, microbiology including bacterial cultures and autoclaving, cell culture including transfections and cell line maintenance * Prior ...
... plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics. Responsibilities * Lead development ...
... plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics. Responsibilities * Lead development ...
... vectors. * Direct the development and optimization of upstream processes including but not limited to: seed train expansion, suspension mammalian cell culture (HEK293/HEK293T), plasmid transient ...
... vectors. * Direct the development and optimization of upstream processes including but not limited to: seed train expansion, suspension mammalian cell culture (HEK293/HEK293T), plasmid transient ...
Associate Scientist II, Bioassays
Madison, WI · On-site
$70K - $80K/yr
... plasmid cloning, AAV packaging, protein expression vectors, microbiology including bacterial cultures and autoclaving, cell culture including transfections and cell line maintenance * Prior ...
Quick apply
Associate Scientist II, Bioassays
Madison, WI · On-site
$70K - $80K/yr
... plasmid cloning, AAV packaging, protein expression vectors, microbiology including bacterial cultures and autoclaving, cell culture including transfections and cell line maintenance * Prior ...
... plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics. Responsibilities * Lead development ...
... plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics. Responsibilities * Lead development ...
... including plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics. * Lead development ...
... including plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics. * Lead development ...
... plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics. Responsibilities * Lead development ...
... plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics. Responsibilities * Lead development ...
Research Scientist
Charlottesville, VA · On-site
Contribute to and lead molecular cloning workflows: guide library construction, vector design, plasmid prep, and verification by NGS. * Partner with computational lab members on bioinformatic ...
Research Scientist
Charlottesville, VA · On-site
Contribute to and lead molecular cloning workflows: guide library construction, vector design, plasmid prep, and verification by NGS. * Partner with computational lab members on bioinformatic ...
... vectors. * Direct the development and optimization of upstream processes including but not limited to: seed train expansion, suspension mammalian cell culture (HEK293/HEK293T), plasmid transient ...
... vectors. * Direct the development and optimization of upstream processes including but not limited to: seed train expansion, suspension mammalian cell culture (HEK293/HEK293T), plasmid transient ...
Research Associate, NGS Assay Development, Virtual Immune System
Chicago, IL · On-site
$70K - $73K/yr
Produce and package lentiviral vectors, troubleshoot viral production workflows, and execute ... plasmid cloning, mammalian cell line maintenance, and lentiviral production, with the ability to ...
Research Associate, NGS Assay Development, Virtual Immune System
Chicago, IL · On-site
$70K - $73K/yr
Produce and package lentiviral vectors, troubleshoot viral production workflows, and execute ... plasmid cloning, mammalian cell line maintenance, and lentiviral production, with the ability to ...
PCR, gateway cloning, restriction digest and T4 ligation, Sanger sequencing of plasmid vectors, RNA work, e.g. CRISPR guide RNA generation, mRNA generation, immunohistochemistry/fluorescence, Western ...
PCR, gateway cloning, restriction digest and T4 ligation, Sanger sequencing of plasmid vectors, RNA work, e.g. CRISPR guide RNA generation, mRNA generation, immunohistochemistry/fluorescence, Western ...
Scientist II, Cell Line Engineering
San Mateo, CA · On-site
$145K - $165K/yr
In depth molecular biology knowledge for plasmid construction and experience selecting expression vectors and promoter types * Experience culturing various cell types, including adherent, suspension ...
Scientist II, Cell Line Engineering
San Mateo, CA · On-site
$145K - $165K/yr
In depth molecular biology knowledge for plasmid construction and experience selecting expression vectors and promoter types * Experience culturing various cell types, including adherent, suspension ...
... plasmid cloning; use of antibodies in various applications; and maintenance of accurate, up-to-date electronic lab records. Familiarity with key antibody properties, protein engineering, viral vector ...
... plasmid cloning; use of antibodies in various applications; and maintenance of accurate, up-to-date electronic lab records. Familiarity with key antibody properties, protein engineering, viral vector ...
... plasmid engineering, protein purification, western blot, tissue culture, transfection, mammalian ... Expertise in project relevant areas, such as HIV replication, vector construction and modification ...
... plasmid engineering, protein purification, western blot, tissue culture, transfection, mammalian ... Expertise in project relevant areas, such as HIV replication, vector construction and modification ...
PCR, gateway cloning, restriction digest and T4 ligation, Sanger sequencing of plasmid vectors, RNA work, e.g. CRISPR guide RNA generation, mRNA generation, immunohistochemistry/fluorescence, Western ...
PCR, gateway cloning, restriction digest and T4 ligation, Sanger sequencing of plasmid vectors, RNA work, e.g. CRISPR guide RNA generation, mRNA generation, immunohistochemistry/fluorescence, Western ...
... plasmid cloning; use of antibodies in various applications; and maintenance of accurate, up-to-date electronic lab records. Familiarity with key antibody properties, protein engineering, viral vector ...
... plasmid cloning; use of antibodies in various applications; and maintenance of accurate, up-to-date electronic lab records. Familiarity with key antibody properties, protein engineering, viral vector ...
Plasmid Vector information
Is Addgene reliable?
Addgene is a reputable nonprofit organization that supplies plasmid vectors to researchers worldwide. It is widely trusted in the scientific community for its quality control, transparent sharing policies, and accurate plasmid documentation. Researchers often rely on Addgene for obtaining verified plasmids for their experiments.
What are some common challenges faced when working as a Plasmid Vector Scientist in a research laboratory?
As a Plasmid Vector Scientist, one of the most common challenges is ensuring the accuracy and efficiency of cloning and vector construction, which often involves troubleshooting issues like low yield, contamination, or unexpected mutations. Managing multiple projects simultaneously and keeping up with rapidly evolving molecular biology techniques can also be demanding. Collaboration with other scientists, such as molecular biologists and bioinformaticians, is essential to streamline workflows and achieve research goals. Staying organized, maintaining meticulous records, and being adaptable to new protocols are key to overcoming these challenges.
What jobs can I do with molecular biology?
With a background in molecular biology, you can pursue roles such as research scientist, laboratory technician, or molecular biologist, often working with techniques like DNA cloning, PCR, and plasmid vector manipulation. These jobs typically require laboratory skills, knowledge of genetic techniques, and sometimes relevant certifications or advanced degrees.
What is the difference between Plasmid Vector vs Cloning Technician?
| Aspect | Plasmid Vector | Cloning Technician |
|---|---|---|
| Required Credentials | Bachelor's in Molecular Biology or related field, lab experience | Associate's or Bachelor's, hands-on lab skills in cloning |
| Work Environment | Research labs, biotech companies | Research labs, biotech manufacturing |
| Industry Usage | Genetic engineering, molecular cloning | Cloning, DNA manipulation, sample preparation |
While a plasmid vector is a DNA molecule used to transfer genetic material, a cloning technician performs laboratory tasks involving DNA cloning techniques. The plasmid vector is a tool, whereas the cloning technician is a professional who uses such tools in laboratory settings to achieve genetic research or product development.
What are plasmid vectors?
Plasmid vectors are small, circular DNA molecules that are used in molecular biology to transfer genetic material into a host cell. They are engineered to contain features such as an origin of replication, selectable markers, and multiple cloning sites, which make them useful tools for cloning, gene expression, and genetic engineering experiments. Plasmid vectors are commonly used to produce proteins, study gene function, and develop genetically modified organisms. Because they can replicate independently within host cells, they are an essential tool in biotechnology and genetic research.
What are the key skills and qualifications needed to thrive as a Plasmid Vector, and why are they important?
I'm sorry, but 'Plasmid Vector' is not a real-world professional occupation and therefore cannot be described in terms of job skills and qualifications.
What is the job of a plasmid?
A plasmid is a small, circular DNA molecule used in genetic engineering to carry and replicate specific genes within a host organism. The role of a plasmid in a laboratory setting involves cloning, gene expression, and genetic modification, often requiring skills in molecular biology techniques and the use of laboratory tools. Understanding plasmid functions is essential for jobs in biotechnology and research environments.
What do plasmid vectors do?
Plasmid vectors are DNA molecules used in molecular biology to carry genetic material into host cells, typically bacteria, for cloning, gene expression, or genetic modification. They enable scientists to replicate, manipulate, and study specific genes efficiently in laboratory settings.
$92K - $126K/yr
Other
Posted 29 days ago
Job description
Reporting to the Associate Director, Upstream Process Development, the Senior Scientist will contribute to upstream viral process development to bring Client's pipeline of T cell and viral vector-based products to the clinic. Responsibilities will include, but are not limited to, performing the day-to-day activities of the viral process development lab, building Client's viral manufacturing capabilities, and executing experiments to support viral process development/characterization. This role will collaborate significantly with research and analytical development teams, as well as contract development and manufacturing organizations.
Key responsibilities: Contribute to the setup and organization of the Client's vector process development capabilities. Develop bench scale suspension culture processes for viral vector generation within shake flasks and bioreactors through design and execution of experiments to support process characterization, and process transfer activities between the research team, TechOps, and external partners. Provide experimental execution, data review and analysis, and maintenance of accurate and detailed lab notebooks.
Perform day-to-day activities in the vector process development lab including maintaining equipment, ordering materials and managing inventory, and preparing buffers and process aids. Author and review technical documents, including but not limited to batch records, SOPs, development reports and process specific sections of regulatory documents. Represent Client externally at meetings (professional associations, with regulatory bodies, etc.)
Serve as a PD subject matter expert on both internal and external teams (CDMO, material & equipment suppliers, etc.). Required experience & skills: Bachelor's Degree with 10 years, Master's Degree with 8 years or Ph.D. with 5 years in chemical engineering, biochemical engineering/bioengineering, biotechnology or related discipline Hands-on experience with viral vector upstream processing, including excellent small-scale aseptic technique and expert understanding of bioreactor operation and control loops
Experience implementing processes in clinical and commercial manufacturing of cell and gene therapy / biopharma products Demonstrated ability to apply knowledge of cell biology, chemical engineering, or bioengineering toward process development, scale-up /scale-down and troubleshooting Strong scientific reasoning, problem-solving, and applied mathematics and statistics skills, including the ability to break down complex problems into manageable hypotheses Proven experience collaborating with internal and external partners Ability to balance individual contributions while training and informally mentoring junior colleagues. Working knowledge of GMP guidelines for clinical and commercial manufacturing Proficiency in using Microsoft Word, Excel, Power Point and data analysis/presentation software such as JMP and/or GraphPad Excellent interpersonal, verbal and written communication skills Strong organizational & problem-solving skills, with excellent attention to detail and the proven ability to collaborate in a dynamic team environment Preferred experience & skills: End-to-end experience in plasmid and Lentivirus development and manufacturing Experience with high-throughput bioreactors systems, namely AMBR, but others will be considered Experience drafting CMC sections for INDs
About Cedent
Sourced by ZipRecruiter
CEDENT strives to attract and retain the best people and provide an environment where they can all develop professionally and build a rewarding career. As a result, we create an inclusive environment that is rich in diversity, acknowledges each individual's uniqueness and promotes respect, personal achievement and stewardship. Our clients are global and so is CEDENT. We build and maintain a global workforce that includes people from different backgrounds, with a vast range of skills and experience all united by a common culture and commitment to help our clients achieve high performance. Cultivating a diverse workforce and inclusive work environment makes business sense. Our peoples varied skills are the talent engine that powers CEDENT, enabling it in turn to deliver the innovative solutions that help our clients outperform competitors.
Industry
It services
Company size
11 - 50 Employees
Headquarters location
Plano, TX, US
Year founded
2008