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Mayo Clinic announces an open-rank tenure-track faculty recruitment dedicated to advancing understanding and developing treatment strategies for autoimmunity in Type 1 diabetes. The position emphasizes the development of novel immunomodulatory or disease-modifying therapeutic approaches, as well as innovative strategies for immune protection and evasion in stem cell-derived islet cells for the treatment of Type 1 diabetes. This role provides a unique opportunity to contribute at the intersection of islet autoimmunity, translational immunology, islet cell biology, transplantation research, and stem cell biology. Mayo Clinic, ranked first in Diabetes and Endocrinology patient care, seeks candidates who demonstrate excellence in collaborative environments and possess a strong record of partnership with clinical colleagues.
Preferred Research Focus and Expertise

• Mechanisms driving the autoimmune process in Type 1 diabetes
• Establishment of immune tolerance in Type 1 diabetes
• Disease-modifying therapies in Type 1 diabetes
• Modelling autoimmunity and human islet destruction in Type 1 diabetes
• Immune modulation of stem cell-derived islet cells for transplantation
• Immune-islet crosstalk during pathogenesis and progression of Type 1 diabetes

Highlights of Mayo Clinic Research Enterprise

• Over 5,000 research personnel, including 321 faculty level research investigators and 948 physicians who are actively involved in research.
• 11,220 peer-reviewed papers were published in 2024.
• Investments in research each year result in hundreds of new clinical trials. In 2024, the institution received over $753 million in extramural research awards supplemented with over $517 million of institutional support.
• Nearly 10,000 active studies involving human participants in progress. More than 5,900 research grants and contracts.
• State-of-the art laboratories and shared resource facilities, including those for microscopy and imaging, cell and molecular biology, animal models, production of iPS cells and clinical grade MSCs, biomedical engineering and mathematics, materials testing, a Medical Genomics Facility, a Mouse Modeling Facility, Molecular and Microscopic Core Facilities, and unique Human Disease Tissue Banks.
• Over 420,000 square feet of research laboratory space includes several robotic freezers capable of storing 3.5 million DNA samples.
• Mayo Clinic supports innovation and has a wealth of resources available - including an integrated health record and collaboration with top specialists.

Qualifications
The position can be located at any of Mayo Clinic's campuses in Rochester, Minnesota; Phoenix, Arizona; or Jacksonville, Florida.
Applications should include a CV with bibliography, cover letter and statement of research interests.
The successful candidate will hold an MD, PhD, or MD/PhD (or equivalent). Candidates with a sustained track record of success in extramural funding (current R01 or R01-equivalent funding as PI) and publications, and who demonstrate excellence in collaborative environments and possess a strong record of partnership with clinical colleagues are preferred.
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.