Pharmaceutical R&D Jobs in Philadelphia, PA (NOW HIRING)

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Job Function:

Career Programs

Job Sub Function:

Post Doc - Data Analytics & Computational Sciences

Job Category:

Career Program

All Job Posting Locations:

Barcelona, Spain, Beerse, Antwerp, Belgium, Madrid, Spain, Raritan, New Jersey, United States of America, Titusville, New Jersey, United States of America

Job Description:

Job description

At J&J we are developing Generative AI solutions to support pharmaceutical R&D, including literature review, evidence synthesis, document Q&A, therapeutic area knowledge search, translational science workflows, and R&D decision support.

These systems need to be tested before teams use them in scientific workflows. In pharmaceutical R&D, a useful AI response depends on the question, user, source material, therapeutic area, and risk of error.

We are looking for a postdoctoral researcher to help design methods that test whether GenAI tools produce answers that are accurate, evidence-grounded, traceable, usable, and appropriate for the intended task.

The role reports to the Associate Director, Generative AI Evaluation & Quality Standards. The team defines how J&J Innovative Medicine evaluates GenAI systems before use and helps determine when they are ready for release, expansion, or improvement.

Key responsibilities

• Design evaluation frameworks, rubrics, and criteria for GenAI tools used across pharmaceutical R&D.
• Develop therapeutic-area-specific criteria with business and scientific teams to reflect domain and use-case quality needs.
• Build benchmark datasets, reference answer sets, annotation guides, and evaluation datasets.
• Run expert reviews with scientific, clinical, regulatory, medical, data science, and engineering teams.
• Test LLM, RAG, and agent performance, including accuracy, source grounding, retrieval quality, citation fidelity, task completion, robustness, safety, and usability.
• Analyze failure patterns such as unsupported claims, incorrect reasoning, poor evidence use, missing uncertainty, weak traceability, or failure to follow instructions.
• Translate evaluation findings into improvements in prompts, retrieval methods, agent workflows, tools, and user experience.
• Help define release criteria for systems moving from prototype to limited release, expanded use, or product support.
• Review emerging evaluation methods and adapt useful approaches for pharmaceutical R&D.
• Document methods, findings, and recommendations so teams can apply consistent evaluation practices.
• Design and develop agentic judge methods to evaluate GenAI outputs against defined criteria, flag evidence gaps or unsupported claims, and support expert review workflows.

QualificationsEducation

• PhD or equivalent research experience in biomedical science, computational biology, bioinformatics, AI/ML, data science, clinical research, regulatory science, biostatistics, pharmaceutical sciences, or a related field.

Experience and skillsRequired

• Understanding of biomedical science, pharmaceutical R&D, therapeutic area science, translational science, clinical development, regulatory science, biomedical informatics, data science, or related areas.
• Experience translating expert judgment into criteria, rubrics, datasets, protocols, or measurable outcomes.
• Experience designing or applying evaluation methods, benchmark datasets, annotation protocols, validation studies, quality reviews, or assessment frameworks.
• Interest in testing GenAI systems, including LLMs, RAG, and AI agents.
• Proficiency in Python and common data science or machine learning tools.
• Ability to analyze model outputs, compare performance, identify failure patterns, and recommend improvements.
• Clear written and verbal communication skills.

Preferred

• Experience with LLM APIs, embeddings, vector databases, prompt engineering, agent frameworks, or AI evaluation tools.
• Experience evaluating retrieval quality, generated answers, multi-step workflows, tool use, scientific reasoning, citation quality, or evidence-grounded outputs.
• Experience designing expert review workflows, annotation instructions, adjudication processes, or inter-rater reliability analyses.
• Domain knowledge in one or more biomedical or therapeutic areas.
• Familiarity with biomedical data standards, structured scientific or clinical data, ontologies, knowledge graphs, CDISC, FHIR, or related frameworks.
• Publications or applied research in AI evaluation, NLP, biomedical informatics, machine learning, data science, computational biology, bioinformatics, or a related field.

Required Skills: GenAI evaluation, Python, data science, benchmarking, rubric design, biomedical research, technical communication.

Preferred Skills: RAG evaluation, agent evaluation, biomedical informatics, expert review, annotation protocols, therapeutic area expertise, responsible AI.

Required Skills:

Preferred Skills:

The anticipated base pay range for this position is:

43,600.00 - 70,150.00

Benefits:

In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees' and companies' performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location's eligible dependents - can participate in several insurance plans. For more information, visit Employee benefits | Supporting well-being & career growth | Johnson & Johnson Careers.

*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.