Part-time work from home jobs exist in a number of industries in fields. These include positions as a personal assistant, data entry or billing specialist, customer service representative, and even a telehealth provider. Home-based jobs are often flexible, but in some positions, you may be part of a shift system where you need to be available during specific hours. Your responsibilities vary depending on your schedule. Most work-from-home flexible administrative jobs require you to have good computer knowledge and the ability to work a remote job. You should have a firm understanding of Microsoft Outlook, Office, and Excel.