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Operations Head Jobs in Brighton, MA (NOW HIRING)

Central Operations Head (COH)

Boston, MA · On-site

$187.20 - $280.80/hr

Summary We are seeking a Central Operations Head (COH) to provide strategic leadership across clinical drug supply, Clinical Trial Agreement (CTA), and eTMF management to support global clinical ...

New

Head cook

Charlestown, MA · On-site

$20 - $24/hr

The Head Cook will also assure compliance with all licensing and accreditation requirements. They ... The above listing is not to be considered as inclusive of all job functions and/or operational ...

Your Role We are hiring a Head of Science Operations to lead the Make and Test engine at the heart of AIDD. Reporting directly to the head of AIDD, this is a senior scientific leadership role with ...

The Head Studio Operations Assistant position is only offered to the greatest contributors and most outstanding performers on our student employee team. Eligibility: Current MPE or CWP student, has ...

The Head Coach oversees the day-to-day operations of the program, including: * planning and conducting practices; * preparing for competition; * developing game strategy; * scheduling contests ...

Cafe Head Chef - Boston

Cambridge, MA · On-site

$73K - $94K/yr

The Cafe Head Chef is responsible for overseeing all kitchen operations within the café and plays a critical role in the success and growth of the kitchen team. Cafe Head Chefs may supervise up to ...

Cafe Head Chef - Boston

Cambridge, MA · On-site

$73K - $94K/yr

The Cafe Head Chef is responsible for overseeing all kitchen operations within the café and plays a critical role in the success and growth of the kitchen team. Cafe Head Chefs may supervise up to ...

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Showing results 1-20

Operations Head information

See Brighton, MA salary details

$37.1K

$117.4K

$195.6K

How much do operations head jobs pay per year?

As of Sep 2, 2026, the average yearly pay for operations head in Brighton, MA is $117,353.00, according to ZipRecruiter salary data. Most workers in this role earn between $82,300.00 and $147,700.00 per year, depending on experience, location, and employer.

What does an operations head do?

An Operations Head oversees the daily operations of a company or organization, ensuring that business processes run smoothly and efficiently. They are responsible for managing teams, streamlining workflows, and implementing policies that support organizational goals. Their role often includes budgeting, resource allocation, and performance monitoring to maximize productivity and profitability. Operations Heads also collaborate with other department leaders to drive strategic initiatives and improve overall business performance.

How does the operations head typically collaborate with other department leaders to achieve organizational goals?

As Operations Head, you will work closely with leaders from departments such as finance, HR, sales, and supply chain to align operational strategies with overall business objectives. Regular cross-functional meetings and strategic planning sessions are common, ensuring that operations support and enhance the goals of each department. Effective communication and problem-solving skills are essential, as you may need to resolve conflicts, optimize processes, and drive company-wide initiatives. This collaborative approach is key to creating streamlined workflows and achieving organizational success.

What are the key skills and qualifications needed to thrive as an operations head, and why are they important?

To thrive as an Operations Head, you need expertise in business operations, process optimization, and leadership, often supported by a degree in business administration or a related field. Familiarity with ERP systems, project management tools, and certifications such as Six Sigma or PMP are typically required. Exceptional problem-solving, strategic thinking, and communication skills help drive teams and foster cross-departmental collaboration. These skills are crucial for ensuring operational efficiency, achieving business goals, and navigating complex organizational challenges.

What is the difference between Operations Head vs Operations Manager?

AspectOperations HeadOperations Manager
ResponsibilitiesStrategic planning, overseeing multiple departments, setting long-term goalsImplementing daily operations, managing teams, ensuring process efficiency
Required CredentialsBachelor's/Master's in Business, MBA often preferredBachelor's in Business or related field, relevant certifications
Work EnvironmentExecutive-level, strategic focus, cross-departmentalOperational focus, team management, process improvement
Industry UsageCommon in large organizations, corporate settingsFound in organizations of all sizes, manufacturing, services

The Operations Head typically holds a strategic, leadership role overseeing multiple departments and setting long-term goals, while the Operations Manager focuses on daily operational activities and team management. Both roles require relevant business credentials, but the Operations Head's scope is broader and more strategic.

How much does an operations head make?

The salary of an Operations Head typically ranges from $80,000 to $200,000 annually, depending on the industry, company size, location, and experience. Senior roles may include bonuses, profit sharing, and other benefits, with higher compensation often linked to leadership skills and operational expertise.

What are the most commonly searched types of Operations jobs in Brighton, MA?

The most popular types of Operations jobs in Brighton, MA are:

What cities near Brighton, MA are hiring for Operations Head jobs?

Cities near Brighton, MA with the most Operations Head job openings:

Infographic showing various Operations Head job openings in Brighton, MA as of August 2026, with employment types broken down into 85% Full Time, 12% Part Time, and 3% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $117,353 per year, or $56.4 per hour.

Central Operations Head (COH)

3M HEALTHCARE

Boston, MA • On-site

$187.20 - $280.80/hr

Other

Posted 2 days ago

New


Job description

Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.

Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.

This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.

The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.

Summary

We are seeking a Central Operations Head (COH) to provide strategic leadership across clinical drug supply, Clinical Trial Agreement (CTA), and eTMF management to support global clinical development programs. This role partners cross-functionally with Clinical, Regulatory, Legal, Technical Operations, and Operational Excellence to ensure alignment on trial needs, risk management, and execution priorities.

You will oversee end-to-end delivery across trials, define outsourcing and vendor strategies, and ensure performance through KPIs, KRIs, and governance. This role is accountable for driving operational excellence, ensuring inspection readiness, and maintaining compliance with global regulations and internal standards.

As a leader, you will build and develop a high-performing team, establish scalable processes and best practices, and foster a culture of accountability, innovation, and continuous improvement in a fast-paced biotech environment.

Your role
  • Provide strategic direction for clinical drug supply management, clinical trial agreement (CTA) management, and eTMF management activities to support clinical development objectives across all programs and trials
  • Collaborate with Trial Management, Regulatory Affairs, Clinical Development, Legal, and Technical Operations to align on trial needs and deliverables
  • Collaborate with Operational Excellence & Clinical Compliance and GMP compliance to align on risk assessment, metrics, KPIs, and KRIs for management of clinical drug supply, CTAs, and eTMF
  • Define and implement outsourcing strategies (incl. Contract Research Organizations (CROs), Contract Manufacturing Organizations (CMOs) and vendors) in partnership with VP of Global Clinical Operations and Head of Clinical Sourcing & Contracting
  • Define functional goals, performance metrics, and resourcing strategies. Drive innovation including adoption of risk-based approaches
  • Oversee end-to-end execution of drug supply-/ CTA-/ and eTMF management across clinical trials, ensuring timely, high-quality, and inspection-ready deliverables
  • Track CRO, CMO, and vendor performance using metrics, KPIs, and KRIs; lead SMO governance meetings to address escalated issues and drive continuous improvement
  • Establish and maintain best practices and standards throughout the trial lifecycle
  • Ensure adherence to global regulatory requirements, GCP and internal SOPs. Lead audit and inspection readiness for drug supply-/ CTA-/ and eTMF management and implement effective oversight models for internal teams and outsourced partners. Perform internal quality reviews and ensure inspection readiness of trial documentation
  • Lead, coach, and develop a high-performing team. Foster a culture of collaboration, continuous learning, and accountability, while supporting career progression and succession planning across the function
  • Select, manage, and govern external vendors. Define expectations, monitor performance via KPIs, and drive accountability through governance forums to ensure quality, timelines, and cost-effectiveness
What You Bring
  • 12+ years of trial management experience with 5+ years in leadership position
  • Bachelor’s degree in Life Sciences, Pharmacy or related field (required). Advanced degree, e.g., MS, PharmD, PhD, MBA (preferred)
  • Significant experience working in global clinical development organization
  • Significant experience in outsourcing and oversight
  • Expert knowledge in ICH GCP and GMP
  • Expert knowledge in computer technologies to plan, forecast, and track documents/ material on all levels
  • Expert knowledge in risk assessment and management on program and trial-level
  • Familiarity with clinical trial systems (e.g., CTMS, eTMF, IRT) and operational metrics, KPIs, and KRIs
  • Familiarity with clinical supply planning, forecasting, and inventory tools
  • Independent judgment and objectivity
  • Strong analytical and influencing skills
  • Ability to drive accountability across functions
  • Strong leadership and interpersonal skills

Salary range: $187,200 - $280,800 USD

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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