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Oncology Informatics Jobs in California (NOW HIRING)

Guardant Health

Staff Business Analyst

Palo Alto, CA · On-site

$72K - $96K/yr

... oncology, clinical data systems, or precision medicine. Deep domain experience is required * Bachelor's or advanced degree in Life Sciences, Bioinformatics, Genomics, Health Informatics, or a related ...

Pfizer

Head of AI Clinical Excellence

San Diego, CA · On-site

$84K - $115K/yr

Expertise in Clinical Development, Oncology, Regulatory Science, Data Science, or Clinical Informatics. * Experience developing and deploying Large Language Models (LLMs), Generative AI, Agentic AI ...

Guardant Health

Staff Business Analyst

Palo Alto, CA

$72K - $96K/yr

... oncology, clinical data systems, or precision medicine. Deep domain experience is required * Bachelor's or advanced degree in Life Sciences, Bioinformatics, Genomics, Health Informatics, or a related ...

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All JobsOncology Informatics JobsOncology Informatics Jobs in California

Oncology Informatics information

See California salary details

$41.9K

$97.1K

$164.3K

How much do oncology informatics jobs pay per year?

As of Aug 23, 2026, the average yearly pay for oncology informatics in California is $97,120.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,100.00 and $120,900.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as an oncology informatics professional?

To thrive as an Oncology Informatics professional, you need a solid background in health informatics, oncology workflows, and data analysis, often supported by a degree in health informatics, nursing, or a related field. Familiarity with electronic health records (EHRs), oncology information systems (OIS), and certifications such as Certified Health Data Analyst (CHDA) or Certified Professional in Healthcare Information and Management Systems (CPHIMS) are frequently required. Strong problem-solving skills, attention to detail, and effective communication are crucial for bridging clinical and technical teams. These competencies ensure accurate data management, support evidence-based care, and enhance clinical outcomes in oncology settings.

What are some typical challenges faced by professionals working in oncology informatics, and how can they be addressed?

Professionals in oncology informatics often encounter challenges such as integrating complex data from disparate sources, ensuring data accuracy, and maintaining patient privacy. They may also face difficulties in standardizing clinical workflows across different systems and collaborating with multidisciplinary teams. Addressing these challenges typically involves staying current with evolving health IT standards, leveraging interoperability tools, and fostering strong communication with clinicians, researchers, and IT staff to promote seamless data exchange and decision-making.

What are popular job titles related to Oncology Informatics jobs in California?

For Oncology Informatics jobs in California, the most frequently searched job titles are:

What job categories do people searching Oncology Informatics jobs in California look for?

The top searched job categories for Oncology Informatics jobs in California are:

What cities in California are hiring for Oncology Informatics jobs?

Cities in California with the most Oncology Informatics job openings:

Oncology Informatics jobs near you
Infographic showing various Oncology Informatics job openings in California as of August 2026, with employment types broken down into 95% Full Time, and 5% Contract. Highlights an 100% In-person job distribution, with an average salary of $97,120 per year, or $46.7 per hour.

Staff Business Analyst

Guardant Health

Palo Alto, CA • On-site

$72K - $96K/yr

Full-time

Re-posted 18 days ago

Guardant Health rating

9.4

Company rating: 9.4 out of 10

Based on 6 frontline employees who took The Breakroom Quiz

3rd of 120 rated laboratories

Job description

Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.
Job Description:
We are seeking a highly motivated Staff Business Analyst with a strong background in genomics and oncology to join our team. You will be embedded at the front of product development for Guardant Health's clinical and genomic data applications. You bring years of direct experience in molecular diagnostics or clinical oncology, and you use that depth daily to shape what gets built, how clinical data is modeled, and what it means for every downstream consumer.
Responsibilities:
  • Stakeholder Engagement: Collaborate with domain owners and business leaders in Real-World Evidence, Medical Affairs, Biopharma, Product management, and Data Engineering to gather and document business requirements. Ensure clarity of needs and objectives specific to genomic data analytics and real-world clinical outcomes.
  • Product Partnership: Operate as part of the product and engineering team, owning the problem space from early discovery through production release. Shape what gets built by driving clarity on requirements, domain and business context.
  • Requirements Ownership: Own requirements end-to-end for clinical and genomic data products. Drive conversations with domain authority, challenge assumptions, identify gaps, and resolve ambiguity independently.
  • Impact Analysis: Assess the full downstream impact when a new assay, product, biomarker, or data source is introduced including changes to how clinical concepts are represented across the platform, data model and business logic updates, and implications for downstream consumers.
  • Data Stewardship: Maintain authoritative documentation of clinical data models, business rules, data mappings, and lineage. Serve as the source of truth for how clinical and genomic concepts are represented and consumed across the platform.
  • User Democratization: Serve as a subject matter expert in oncology and genomic data workflows, providing guidance to users and stakeholders. Facilitate user training and support the adoption of new product features.

Qualifications:
  • 7+ years as a Business Analyst or equivalent, with the majority spent in genomics, molecular diagnostics, oncology, clinical data systems, or precision medicine. Deep domain experience is required
  • Bachelor's or advanced degree in Life Sciences, Bioinformatics, Genomics, Health Informatics, or a related scientific discipline.
  • Expert-level written and verbal communication, documenting data specifications, and stakeholder communications that are clear, precise, and actionable without further interpretation. You are equally effective in a room of clinicians, a product review, or an engineering planning session.
  • Hands-on experience building or supporting clinical or genomic data applications.
  • Querying data, running data analysis on analytics databases.
  • Deep working knowledge of genomic data: variants, biomarkers, assay panels, clinical annotations, and how these translate into structured data within production systems.
  • Experience in HIPAA-compliant healthcare environments. Familiarity with clinical data governance and data quality standards.

AI & Digital Fluency
  • Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.

Hybrid Work Model:This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate's compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need.Primary Location: Palo Alto, CAPrimary Location Base Pay Range: $142,300 - $195,700Other US Location(s) Base Pay Range: $120,955 - $166,345If the role is performed in Colorado, the pay range for this job is: $128,070 - $176,130
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.
Please visit our career page at: http://www.guardanthealth.com/jobs/

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