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On Call Phage Display Scientist Jobs (NOW HIRING)

Prellis Biologics, Inc.

$111 - $169/hr

Expanding our display platform portfolio -- deploying new display formats (yeast, phage, mammalian ... Scientist (PhD + 2+ years relevant industry experience) or Principal Associate Scientist (BSc/MSc ...

Elanco

Senior Analyst - Discovery Research

Indianapolis, IN · On-site

$110K - $111K/yr

OR Bachelor's degree in a related scientific field with 2-4 years of relevant laboratory experience ... Experience with antibody discovery platforms, including single-B cell workflows, phage display, and ...

Wisconsin

Lab Technician

Madison, WI · On-site

$19.23/hr

Our basic science and translational research programs have made fundamental discoveries in cell and ... Experience with phage-display technologies. * Experience with DNA and proteins (purification ...

MSD

Scientist

Gaithersburg, MD · On-site

$101K - $154K/yr

D. in Life Sciences, Engineering or related field preferred. o Additional postdoctoral or ... Phage display, antibody discovery (or antibody engineering), and molecular biology OR structural ...

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Associate Scientist, Display Technologies

BigHat Biosciences

San Mateo, CA • On-site

$120K - $135K/yr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 26 days ago

Job description

The role: BigHat Biosciences is seeking a curious and motivated Associate Scientist to join the Display Technologies team. This individual will contribute to BigHat's antibody discovery and engineering efforts and help generate high-quality data to improve BigHat's machine learning models using display technologies, working closely with senior scientists and cross-functional teams.
*At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate. 
  • Support R&D projects advancing display technologies at BigHat that expands BigHat's antibody discovery capabilities and feed its ML models.
  • Lead in the construction and QC of phage and yeast display libraries across diverse antibody formats (VHH, scFv, Fab) using standard molecular biology techniques (PCR, molecular cloning, electroporation).
  • Execute phage and yeast display selections using naive and affinity and stability maturation libraries to discover and engineer antibodies with desired therapeutic properties.
  • Express, purify, and characterize display-derived molecules using assays including ELISA, flow cytometry, BLI/SPR, CE-SDS, and others.
  • Analyze selection results and contribute to discussions on next steps and future experimental design.
  • Collaborate with BigHat's Data Science and Machine Learning teams to inform library design and interpret selection data for model training.
  • Present experimental plans and results during regular meetings with manager and science teams.
  • Maintain thorough records using LIMS and electronic notebooks.
  • BS or MS in Biochemistry, Molecular Biology, Bioengineering, or a related field.
  • 4+ years of hands-on laboratory experience (academic or industry); relevant internship or research experience welcome.
  • Familiarity with general molecular biology techniques (PCR, molecular cloning, gel electrophoresis).
  • Exposure to antibody biology, display technologies (phage or yeast), and protein expression.
  • Demonstrated ability to follow protocols carefully, troubleshoot experiments, and maintain detailed lab records.
  • Effective time management and clear written and verbal communication skills.
  • Collaborative, team-oriented mindset with an eagerness to learn in a fast-paced startup environment.
  • Nice-to-haves include experience with flow cytometry, ELISA, or other binding assays, and familiarity with NGS or automation platforms.
The salary estimated for this position is $120,000 - $135,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match 
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave

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