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Oligonucleotide Synthesis Jobs in Bothell, WA (NOW HIRING)

Manager of Quality Assurance

Redmond, WA · On-site

$100K - $120K/yr

Apply Quality by Design principles to define robust, integrated control strategies for the oligonucleotide, synthetic gene, mRNA, and formulation manufacturing processes. * Oversee and manage the ...

Oligonucleotide Synthesis information

What is oligonucleotide synthesis?

An Oligonucleotide Synthesis job involves the production of short DNA or RNA sequences using automated synthesizers and chemical processes. Professionals in this role prepare reagents, operate synthesis equipment, and conduct quality control to ensure high-purity oligonucleotides. They often work in biotechnology, pharmaceutical, or research laboratories, contributing to applications in genetics, diagnostics, and therapeutics. Strong attention to detail, knowledge of chemical synthesis, and familiarity with purification techniques are essential for success in this field.

What are the key skills and qualifications needed to thrive in oligonucleotide synthesis?

To thrive in Oligonucleotide Synthesis, you need a solid background in molecular biology or chemistry, strong laboratory skills, and often a bachelor's degree in a related field. Experience with automated DNA/RNA synthesizers, HPLC, and mass spectrometry, as well as knowledge of laboratory information management systems (LIMS), is typically required. Attention to detail, problem-solving abilities, and effective teamwork are key soft skills for this role. These qualifications are critical for ensuring high-quality, accurate synthesis results and efficient workflow in a fast-paced laboratory environment.

What are some common challenges faced in oligonucleotide synthesis?

Professionals in Oligonucleotide Synthesis often encounter challenges such as maintaining high purity and yield in complex synthesis processes, troubleshooting instrument malfunctions, and adhering to stringent quality standards. The work can involve repetitive tasks and the need to closely follow protocols, which requires strong focus and meticulousness. Collaborating effectively with research scientists, quality control, and production teams is also essential to resolve issues quickly and ensure smooth project progression. Being proactive about troubleshooting and communication can greatly enhance both individual and team performance in this role.

What job categories do people searching Oligonucleotide Synthesis jobs in Bothell, WA look for?

The top searched job categories for Oligonucleotide Synthesis jobs in Bothell, WA are:

What cities near Bothell, WA are hiring for Oligonucleotide Synthesis jobs?

Cities near Bothell, WA with the most Oligonucleotide Synthesis job openings:

Infographic showing various Oligonucleotide Synthesis job openings in Bothell, WA as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Formulation Manufacturing Associate

Bothell, WA • On-site

$30/hr

Full-time

Posted 3 days ago

New


Job description

Summary
Formulates oligonucleotide probes, primers and assays (RUO, ASR, EUA & 510K). Manages oligo stocks inventory. Assists Manager in managing RUO, ASR, EUA and 510K products inventory.
Essential Duties and Responsibilities
  • Dissolves and dilutes oligonucleotide synthesis products, analyzes concentration, formulates assays (RUO, ASR, EUA & 510K), prints labels according to specifications and apply labels to product tubes.
  • Formulate solutions mixes according to SOPs and Work Sheets (WS) to prepare finished products.
  • Prepare and submit oligo samples for Mass Spec analysis.
  • Manages oligo stocks inventory.
  • Assists Director/Manager in managing RUO, ASR, EUA and 510K products inventory.
  • Manufactures stocks of raw materials and buffers, and maintains lab supplies, etc.
  • Calibrates and maintains lab equipment as required.
  • Makes inventory corrections and consumptions in NAV.
  • Writing manufacturing operating procedures that are technically sound, promote effective and efficient operations, and comply with cGMP requirements. Edit SOP, SEPC, Work Sheet and related documentation when needed.
  • Initiating and owning quality records, including but not limited to non-conformances (NC), Corrective/Preventative (CAPA).
  • Provides input to process improvements and assists with the development of new and/or improved manufacturing procedures.
  • Assists with related special projects, as required.

Qualifications
• Bachelor's degree (B.S.) in a scientific discipline (chemistry, molecular biology, biochemistry or related field) from four-year college or university with 0-3 years of experience including relevant industry experience in an FDA regulated company preferably in manufacturing and/or quality control.
• General computer skills utilizing various software applications.
• Experience in NAV
Preferred
• Experience with Mass Spectrometer and/or spectrophotometer plate reader.
• Proven knowledge of cGMP requirements to ensure compliance.