ZipRecruiter

Log In

1

Nucleic Acid Delivery Jobs (NOW HIRING)

APN Software Services Inc

Scientist I

San Diego, CA · On-site

In this hands-on laboratory role, you will work closely with senior scientists to execute and optimize the synthesis of targeted and non-targeted lipid nanoparticles (LNPs) for nucleic acid delivery.

BEPC INC

Be Seen First

Oligonucleotide Scientist II

South San Francisco, CA · On-site

$45 - $49.65/hr

This role will support the Nucleic Acid Design and Discovery team within the Protein Sciences ... Experience in oligonucleotide therapeutics delivery and large-molecule drug discovery is preferred.

previous pagenext page

Showing results 21-40

All JobsTechnology JobsNucleic Acid Delivery Jobs

Nucleic Acid Delivery information

See salary details

$11

$16

$22

How much do nucleic acid delivery jobs pay per hour?

As of Sep 13, 2026, the average hourly pay for nucleic acid delivery in the United States is $16.82, according to ZipRecruiter salary data. Most workers in this role earn between $14.42 and $18.75 per hour, depending on experience, location, and employer.

What is nucleic acid delivery?

Nucleic acid delivery refers to the process of transporting genetic material, such as DNA or RNA, into cells for therapeutic or research purposes. This is a critical step in gene therapy, vaccine development, and various biomedical applications, as nucleic acids are often too large and negatively charged to enter cells on their own. Specialized delivery systems, like lipid nanoparticles, viral vectors, or polymers, are used to protect and efficiently transport nucleic acids to target cells. Effective delivery is essential for achieving desired biological effects and minimizing side effects.

What are the key skills and qualifications needed to thrive in nucleic acid delivery?

To thrive in Nucleic Acid Delivery, a strong background in molecular biology, biochemistry, and biotechnology—often supported by an advanced degree—is essential. Familiarity with techniques such as nanoparticle formulation, CRISPR/Cas systems, and analytical tools like PCR and HPLC, as well as experience with regulatory guidelines, is typically required. Strong problem-solving skills, meticulous attention to detail, and effective teamwork are crucial soft skills in this field. These abilities are vital to ensure the safe and efficient delivery of genetic material, driving innovation and therapeutic success.

What are common challenges faced when working in nucleic acid delivery roles and how are they typically addressed?

Professionals in nucleic acid delivery often encounter challenges such as ensuring the stability of nucleic acids during formulation, achieving efficient cellular uptake, and minimizing off-target effects or immune responses. Addressing these challenges requires close collaboration with multidisciplinary teams, including chemists, biologists, and engineers, to optimize delivery vehicles and protocols. Staying updated with the latest advancements and troubleshooting experimental outcomes are integral parts of the daily responsibilities in this field.

Oligonucleotide Scientist II

South San Francisco, CA • On-site

Talent Software Services, Inc
See more jobs at Talent Software Services, Incexternal

Other

This job post has expired 2 days ago. Applications are no longer accepted.

Job description

Working Model: Fully on-site, South San Francisco, CA
Working Days: Monday to Friday
Working Hours: Standard 8 hour shift
Interview Format: One Round (30 minutes) - Local candidates should join the interviews on site, candidates outside of the immediate area may join virtually.
The Position:
We are seeking a creative, self-motivated, collaborative Contractor/Scientist-II to join the
Nucleic Acid Design and Discovery (NADD) team within ProteinSciences (PS) department at
***. We are looking for a candidate with experience in oligonucleotide discovery and
synthesis to support our new oligonucleotide therapeutics discovery group. Experience in
delivery of oligonucleotide therapeutics, large molecule drug discovery, would be preferred. The
successful candidate will join an interdisciplinary chemistry team working in RNAi biology
research and will contribute positively to its developing culture.
Key Responsibilities:
. The candidate will work in an oligonucleotide therapeutic drug discovery research lab
and interface across different therapeutic areas, including neuroscience, immunology
and oncology, to help build a comprehensive therapeutic discovery strategy.
. Good understanding and also troubleshooting experience in oligonucleotide synthesis,
impurity profiling is a plus.
. Collaborate with other scientists to maintain common lab equipment such as oligo
synthesizers, HPLC and desalting units.
. Perform literature reviews, propose, and execute nucleic acid chemistry plans,
coordinate chemistry and biology data to support oligonucleotide compound
progression.
. Establish methods for scaled-up synthesis of lead molecules and coordinate material
delivery for preclinical studies.
. Maintaining a high level of productivity in the laboratory setting to meet the timelines
for in vitro and in vivo studies.
Requirements:
. The candidate must have hands-on experience in oligonucleotide synthesis using
automated oligo synthesizers, Client nucleic acid chemistry, oligonucleotide purification
and characterization using HPLC and mass spectrometry.
. The qualified individual will possess a BS/MS in Organic Chemistry or related discipline.
. The pharmaceutical or biotechnology industry experience in research and development
of RNAi therapeutics is preferred.
. A good understanding of nucleic acid therapeutic modalities, modification chemistries,
sequence selection, and mechanism of action is preferred. Relevant experience in
oligonucleotide therapeutics, large molecule drug discovery, oligonucleotide delivery or
bio-conjugation is desirable.
. Good communication and interpersonal skills are essential and will be evaluated during
the interview process.
. The ideal candidate should be highly motivated and have strong problem-solving,
analytical, communication and organizational skills.

Apply