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Nextflow Bioinformatics Jobs in Silver Spring, MD

Axle

Bioinformatics Engineer

Rockville, MD · On-site

... Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types • Architect scalable solutions capable of processing thousands of ...

Axle

Bioinformatics Engineer

Rockville, MD

Axle is seeking a Bioinformatics Engineer to join our vibrant team at the National Institutes of ... Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant ...

Axle

Bioinformatics Engineer

Rockville, MD · On-site

Axle is seeking a Bioinformatics Engineer to join our vibrant team at the National Institutes of ... Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant ...

Axle

Bioinformatics Engineer

Rockville, MD

Axle is seeking a Bioinformatics Engineer to join our vibrant team at the National Institutes of ... Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant ...

Axle

Bioinformatics Scientist

Bethesda, MD · On-site

Address bioinformatics, scientific computing, and data analysis needs of users within the Division ... Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools ...

Axle

Bioinformatics Scientist

Bethesda, MD

Address bioinformatics, scientific computing, and data analysis needs of users within the Division ... Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools ...

Axle

Bioinformatics Scientist

Bethesda, MD

Address bioinformatics, scientific computing, and data analysis needs of users within the Division ... Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools ...

BCC-NIH

Staff Scientist

Bethesda, MD

PhD in Computer Science, Computational Biology, Bioinformatics, or a related field * Minimum of 5 ... Familiarity with workflow orchestration tools (e.g., Nextflow, Snakemake, Airflow) * Experience ...

BCC-NIH

Staff Scientist

Bethesda, MD · On-site

PhD in Computer Science, Computational Biology, Bioinformatics, or a related field * Minimum of 5 ... Familiarity with workflow orchestration tools (e.g., Nextflow, Snakemake, Airflow) * Experience ...

All JobsNextflow Bioinformatics JobsNextflow Bioinformatics Jobs in Silver Spring, MD

Nextflow Bioinformatics information

See Silver Spring, MD salary details

$61.5K

$97.7K

$154.6K

How much do nextflow bioinformatics jobs pay per year?

As of Jul 14, 2026, the average yearly pay for nextflow bioinformatics in Silver Spring, MD is $97,665.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,800.00 and $133,900.00 per year, depending on experience, location, and employer.

What is the difference between Nextflow Bioinformatics vs Bioinformatics Analyst?

AspectNextflow BioinformaticsBioinformatics Analyst
CredentialsTypically requires a degree in bioinformatics, computer science, or related fields; familiarity with scripting and workflow management toolsUsually holds a degree in bioinformatics, biology, or related disciplines; strong analytical and programming skills
Work EnvironmentResearch labs, biotech companies, or academic institutions; focuses on developing and executing computational workflowsData analysis in research or clinical settings; interprets biological data and reports findings
Industry UsageUsed in genomics, transcriptomics, and large-scale data processing projectsApplied in research, healthcare, and diagnostics to analyze biological datasets

While both roles require bioinformatics knowledge, Nextflow Bioinformatics specializes in managing and automating computational workflows using tools like Nextflow, whereas Bioinformatics Analysts focus on analyzing biological data and interpreting results. The roles often overlap but differ in technical focus and responsibilities.

What are the key skills and qualifications needed to thrive as a Nextflow Bioinformatics specialist, and why are they important?

To thrive as a Nextflow Bioinformatics specialist, you need a strong background in bioinformatics, scripting languages (such as Python or Bash), and experience with workflow management systems, often supported by a relevant degree in bioinformatics, biology, or computer science. Proficiency with Nextflow, containerization platforms (like Docker or Singularity), and high-performance computing environments is typically required. Problem-solving ability, strong attention to detail, and effective collaboration are critical soft skills in this role. These competencies are essential for developing reproducible, scalable analysis pipelines that drive accurate biological insights in research or clinical settings.

What are some common challenges faced when developing and maintaining Nextflow pipelines in a bioinformatics team?

One common challenge in developing and maintaining Nextflow pipelines is ensuring reproducibility and compatibility across different computing environments, such as local clusters and cloud platforms. Collaborating with team members often involves integrating diverse tools and datasets, which can introduce version conflicts or software dependency issues. Additionally, keeping pipelines up-to-date with rapidly evolving bioinformatics methods requires strong communication and regular code reviews within the team. Effective documentation and modular pipeline design can help address these challenges and streamline collaborative workflows.

What is a Nextflow Bioinformatician?

A Nextflow Bioinformatician is a specialist who uses the Nextflow workflow management system to design, implement, and maintain computational pipelines for analyzing biological data. They typically work with large-scale sequencing datasets, automating processes such as data preprocessing, alignment, variant calling, and more. Their expertise lies in combining programming skills with bioinformatics knowledge to streamline and reproduce complex analyses, often in high-performance or cloud computing environments. This role is critical for ensuring reliable, scalable, and reproducible results in genomics and other life science research.
What are popular job titles related to Nextflow Bioinformatics jobs in Silver Spring, MD? For Nextflow Bioinformatics jobs in Silver Spring, MD, the most frequently searched job titles are:
What job categories do people searching Nextflow Bioinformatics jobs in Silver Spring, MD look for? The top searched job categories for Nextflow Bioinformatics jobs in Silver Spring, MD are:
What cities near Silver Spring, MD are hiring for Nextflow Bioinformatics jobs? Cities near Silver Spring, MD with the most Nextflow Bioinformatics job openings:
Nextflow Bioinformatics jobs near you
Bioinformatics Engineer

Bioinformatics Engineer

Axle

Rockville, MD • On-site

Full-time

Posted 21 days ago

Job description

Job Summary:
Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications. They are seeking a Bioinformatics Engineer to join their team supporting major pharmaceutical clients, focusing on optimizing and integrating bioinformatics workflows for high-throughput sequencing analysis.
Responsibilities:
• Evaluate existing bioinformatics pipelines for performance, accuracy, and maintainability, identifying opportunities for optimization and enhancement
• Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types
• Architect scalable solutions capable of processing thousands of samples efficiently on Google Cloud Platform
• Optimize data input/output operations across pipeline modules to minimize bottlenecks and reduce computational costs
• Prepare and structure analysis outputs for visualization platforms and downstream statistical or machine learning applications
• Implement best practices for workflow versioning, containerization, testing, and documentation
• Collaborate with computational biologists, data scientists, and software engineers to integrate pipelines into broader analytical ecosystems
• Stay current with advances in sequencing technologies and analytical methods, evaluating and incorporating new tools as appropriate
Qualifications:
Required:
• Master's degree in bioinformatics, computational biology, computer science, or a related field (or equivalent experience)
• 3+ years of hands-on experience developing and maintaining bioinformatics pipelines in a production environment
• Proficiency with Nextflow (DSL2) and familiarity with workflow management concepts
• Strong experience with RNA-seq analysis (both bulk and single-cell) and DNA sequencing workflows (variant calling, methylation)
• Working knowledge of Google Cloud Platform services (Compute Engine, Cloud Storage, Batch, Life Sciences API, or similar)
• Proficiency in Python and/or R for scripting, data manipulation, and tool development
• Experience with containerization technologies (Docker, Singularity)
• Familiarity with version control systems (Git) and CI/CD practices
• Strong understanding of genomic file formats (FASTQ, BAM, VCF, BED) and common bioinformatics tools (STAR, Salmon, BWA, GATK, Bismark, Cell Ranger, Seurat, Scanpy)
Preferred:
• PhD in a relevant field
• Experience with nf-core pipelines and community standards
• Familiarity with workflow orchestration at scale (Cromwell, AWS Batch, or similar platforms)
• Experience optimizing cloud costs and resource utilization for large-scale genomics workloads
• Knowledge of data visualization tools and frameworks (e.g., R Shiny, Plotly, custom dashboards)
• Experience in pharmaceutical, biotech, or regulated research environments
• Familiarity with FAIR data principles and metadata standards
Company:
At Axle, we are driven by the mission to accelerate discovery and enhance organizational outcomes by revolutionizing operations with our innovative solutions. Founded in 2002, the company is headquartered in Rockville, USA, with a team of 501-1000 employees. The company is currently Late Stage.

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