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Next Generation Sequencing Jobs in Dallas, TX (NOW HIRING)

We are seeking a highly motivated next generation sequencing (NGS) Scientific Fellow to support Oncology Assay Development at Quest. As a member of the Oncology R&D team, this role will collaborate ...

Scientist - Fellow

Lewisville, TX · On-site

$125 - $150/hr

We are seeking a highly motivated next generation sequencing (NGS) Scientific Fellow to support Oncology Assay Development at Quest. As a member of the Oncology R&D team, this role will collaborate ...

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Next Generation Sequencing information

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How much do next generation sequencing jobs pay per year?

As of Sep 8, 2026, the average yearly pay for next generation sequencing in Dallas, TX is $65,835.00, according to ZipRecruiter salary data. Most workers in this role earn between $38,700.00 and $82,500.00 per year, depending on experience, location, and employer.

What is next generation sequencing?

A Next Generation Sequencing (NGS) job involves working with advanced DNA and RNA sequencing technologies to analyze genetic material. Professionals in this field may design experiments, prepare biological samples, operate sequencing instruments, and interpret genomic data. Roles can vary from research scientists and bioinformaticians to lab technicians and data analysts. NGS is widely used in medicine, agriculture, and biotechnology for applications such as disease research, personalized medicine, and evolutionary studies. Strong skills in molecular biology, computational analysis, and data interpretation are typically required.

What does someone working in next generation sequencing do?

Professionals in Next Generation Sequencing typically spend their days preparing and processing biological samples, operating sequencing instruments, and analyzing genomic data. They are responsible for troubleshooting technical issues, maintaining laboratory equipment, and ensuring quality control throughout the sequencing workflow. Collaboration with cross-functional teams—such as bioinformaticians, clinicians, and research scientists—is common to interpret sequencing results and contribute to project goals. This role also involves detailed record-keeping and adherence to regulatory or laboratory standards, making organization and communication important aspects of the job.

What are the key skills and qualifications needed to thrive in next generation sequencing?

To excel in a Next Generation Sequencing (NGS) role, you need a strong background in molecular biology, genomics, and data analysis, often supported by a degree in a life science field. Proficiency with NGS platforms (such as Illumina or Oxford Nanopore), laboratory automation tools, and bioinformatics software is highly valued, alongside relevant certifications in genomics or molecular diagnostics. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills set successful professionals apart. These competencies ensure high-quality sequencing results, efficient workflow, and productive collaboration in fast-paced research or clinical environments.

What are popular job titles related to Next Generation Sequencing jobs in Dallas, TX?

For Next Generation Sequencing jobs in Dallas, TX, the most frequently searched job titles are:

What job categories do people searching Next Generation Sequencing jobs in Dallas, TX look for?

The top searched job categories for Next Generation Sequencing jobs in Dallas, TX are:

What cities near Dallas, TX are hiring for Next Generation Sequencing jobs?

Cities near Dallas, TX with the most Next Generation Sequencing job openings:

Infographic showing various Next Generation Sequencing job openings in Dallas, TX as of August 2026, with employment types broken down into 92% Full Time, and 8% Contract. Highlights an 92% In-person, and 8% Remote job distribution, with an average salary of $65,835 per year, or $31.7 per hour.

NGS Data Scientist (Hybrid)

Quest Diagnostics

Lewisville, TX • On-site

Full-time

Re-posted 24 days ago


Key responsibilities

  • Perform bioinformatic analysis of genomics data from next generation sequencing, including WES, WGS, and targeted DNA and RNA panels.

  • Design, develop, and deploy scalable bioinformatics pipelines to support assay development, validation, and high throughput implementation.

  • Monitor, troubleshoot, and improve sequence analysis workflows and automation to meet strict turnaround times.


ExamOne rating

6.6

Company rating: 6.6 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

94th of 121 rated laboratories


Job description


We are seeking a highly motivated next generation sequencing (NGS) data analytic scientist to support Oncology Assay Development at Quest. As a member of the Oncology R&D team, this role will collaborate with other scientists and staff from cross-functional teams to develop, validate, and support cutting-edge genomic assays for oncology applications.
The ideal candidate will have a strong background in bioinformatics and/or genomic data analysis for somatic applications, translating complex data into actionable insights that drive product development, operational excellence and clinical impact.
This professional will work in a hybrid capacity requiring 3 days onsite at our Lewisville, TX facility.
Responsibilities
  • Perform bioinformatic analysis of genomics data from next generation sequencing. Specific data types include whole exome sequencing (WES), whole exome sequencing (WGS), and targeted DNA and RNA panel datasets generated from Illumina, Ion Torrent and PacBio sequencing technologies.
  • Curate, analyze, and interpret complex genomics datasets to support assay development, validation, and high throughput implementation
  • Present findings to drive decision-making in R&D product development, troubleshooting, and pipeline improvement
  • Design, develop, and deploy scalable and robust bioinformatics pipelines to support analytical validation data analysis for new oncology products
  • Partner with R&D, automation, laboratory operations, and software teams to understand and address the technical challenges and implement efficient solutions
  • Support production day-to-day operations, quickly pivoting focus to respond to incidents and requests
  • Monitor, execute, and improve sequence analysis workflows and automation
  • Produce charts and visualization for dashboards, reporting, and in support of data driven hypothesis testing
  • Track, troubleshoot and mitigate issues encountered in processing production samples to meet strict Turnaround Times (TAT)
  • Contribute to continuous improvement of analytical methods, workflows, and data quality standards

Qualifications
The ideal candidate will have a history of using bioinformatic technical skills to deliver accurate and timely results.
Required Work Experience:
  • Requires at least 4 (four) years of relevant industrial experience in data science and/or bioinformatics role
  • Master's degree, or a Ph.D. in bioinformatics, computational biology, molecular biology, chemistry, physics, statistics, or a related field
  • Experience with oncology genomics and somatic variant analysis

Preferred Work Experience:
  • Experience in NGS workflow development
  • Strong analytical skills with the ability to interpret and communicate experimental results
  • Ability to work collaboratively in a fast-paced, Cross-functional environment.
  • Experience with Software Development Life Cycle documentation procedure
  • Familiarity with assay validation, regulatory environment (CAP/CLIA), or clinical diagnostics

Skills:
  • Experience using scripting languages (Python, R, or similar) for scientific data analysis and visualization
  • Strong proficiency in NGS data processing, QC, and interpretation
  • Experience with analysis of next-generation sequencing data, preferably including Whole-Genome Sequencing, Variant calling, and Annotation
  • Excellent communication skills and the desire to work in a dynamic and collaborative environment

About the Team
Quest Diagnostics honors our service members and encourages veterans to apply.
While we appreciate and value our staffing partners, we do not accept unsolicited resumes from agencies. Quest will not be responsible for paying agency fees for any individual as to whom an agency has sent an unsolicited resume.
Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets or any other legally protected status.

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