Neuroscience Engineering Jobs in California (NOW HIRING)

Aspen Neuroscience is seeking a Scientist II, Bioinformatics QC to join our team. In this role you will be taking ownership of a critical priority, bringing together multiple teams and ensuring the quality of our product, contributing directly to delivering novel cell therapy to patients. You will be responsible for applying bioinformatics and genomics expertise supporting Quality Control operations for clinical-stage cell therapy manufacturing. In being responsible for executing and analyzing multi-omics QC workflows, as well as improving our bioinformatics processes, you will directly impact & influence the lives of patients with Parkinsons Disease. This is an on-site role in Torrey Pines, CA that requires flexibility and availability for weekend and holiday work as needed. Relocation is not available.

DUTIES AND RESPONSIBILITIES:

• Execute bioinformatics QC analyses across multi-omics assays (e.g., RNA-seq, WGS, structural variation, epigenetic profiling) to support product quality assessment and release
• Analyze and interpret data against established acceptance criteria; escalate atypical results and support investigation activities
• Prepare and maintain compliant documentation supporting QC review, deviation investigations, and audit readiness
• Support root cause analysis and re-analysis workflows for QC deviations and process excursions
• Maintain traceability of data, methods, and outputs in alignment with GMP and data integrity expectations
• Collaborate with QC, QA, Manufacturing, and R&D teams to support sample processing timelines and data delivery
• Contribute to process improvements, workflow optimization, and automation initiatives for bioinformatics QC
• Assist in development and evaluation of new analytical methods to support characterization of product lots and intermediates
• Support qualification and validation activities for bioinformatics pipelines and systems

EDUCATION AND EXPERIENCE:

• PhD in Bioinformatics, Genomics, Computational Biology, or related field (or equivalent combination of education and relevant experience)
• Hands-on experience with NGS data analysis pipelines (RNA-seq, WGS, or similar)
• 3 or more years of experience working in the life sciences industry or other regulated environments (GMP/GxP), including understanding of data integrity expectations

JOB SPECIFICATIONS:

• Genomics Expertise: Strong understanding of human genetics and genomics, including variant analysis, gene expression, and structural variation in applied settings
• Programming: Proficiency in scripting and data analysis tools (e.g., Python, R, Bash) to support reproducible workflows
• Data Quality: Excellent attention to detail with demonstrated ability to produce accurate, high-quality, and traceable datasets
• QC/QA Processes: Familiarity with QC and QA workflows, documentation practices, and audit readiness requirements
• Biological Interpretation: Ability to interpret biological and genomics data in clinical or translational contexts to support QC decision-making
• Communication: Strong written and verbal communication skills, with the ability to clearly document and explain analytical methods and results
• Scientific Judgment: Comfort working with ambiguity and applying scientific reasoning to analyze and troubleshoot real-world datasets
• Validation & Systems: Exposure to qualification and validation of bioinformatics systems and pipelines in regulated environments
• Workflow Design: Ability to contribute to the design, improvement, and scaling of bioinformatics workflows and organizational systems

WORKING CONDITIONS

Office and Lab environment. While performing the duties of this Job, the employee is frequently exposed to toxic or caustic chemicals. This is an indoor position requiring the ability to perform experiments in the laboratory, and type and use a computer. No Cleanroom access needed

PHYSICAL DEMANDS

While performing the duties of this Job, the employee is regularly required to stand; walk; sit; use hands to finger, handle, or feel; reach with hands and arms and talk or hear. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision, distance vision, color vision, peripheral vision, depth perception and ability to adjust focus. These work environment characteristics are representative of the environment the job holder will encounter. Reasonable accommodation may be made to enable people with disabilities to perform the essential functions of the job.

EEO and Employment Eligibility:

Aspen Neuroscience is committed to providing equal employment opportunities to all employees and job applicants and prohibits discrimination and harassment of any type. We are committed to creating an inclusive environment for all employees. Aspen is not able to provide visa sponsorship for this role. Applicants must have valid work authorization that does not require employer sponsorship now or in the future.

Total Rewards and Culture:

Aspen Neuroscience, Inc., located in scenic Torrey Pines, is noted for its collaborative and learning focused culture where each person is valued for contributing their strengths and energy to building a world-class line of products for patients in need. The company offers a competitive total compensation package, time-off in addition to Company observed holidays, Medical/Dental insurance benefits, onsite gym, and other wellness perks.

The anticipated salary range for candidates who will work in San Diego is $129,600-$158,400 annually. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc.  Aspen Neuroscience is multi-state employer, and this salary range may not reflect positions that work in other states.