PhD in Structural Biochemistry with experience in protein engineering, purification of challenging targets, design and mutagenesis * The appointee must have greater than 5 years of postdoctoral ...
PhD in Structural Biochemistry with experience in protein engineering, purification of challenging targets, design and mutagenesis * The appointee must have greater than 5 years of postdoctoral ...
Research Associate, Senior
Durham, NC · On-site
PhD in Structural Biochemistry with experience in protein engineering, purification of challenging targets, design and mutagenesis * The appointee must have greater than 5 years of postdoctoral ...
Research Associate, Senior
Durham, NC · On-site
PhD in Structural Biochemistry with experience in protein engineering, purification of challenging targets, design and mutagenesis * The appointee must have greater than 5 years of postdoctoral ...
Typical laboratory techniques often require expertise with gene expression analysis, targeted mutagenesis, microscopy, bacterial community analysis, and multiple `omics analysis. Demonstrable ...
Typical laboratory techniques often require expertise with gene expression analysis, targeted mutagenesis, microscopy, bacterial community analysis, and multiple `omics analysis. Demonstrable ...
Research Associate
San Francisco, CA · On-site
$95K - $120K/yr
Molecular biology (cloning, mutagenesis, plasmid prep) * Protein biochemistry (expression, purification, assays) * Cell biology (culture, transfection, imaging) * Neuroscience (in vivo experiments ...
Research Associate
San Francisco, CA · On-site
$95K - $120K/yr
Molecular biology (cloning, mutagenesis, plasmid prep) * Protein biochemistry (expression, purification, assays) * Cell biology (culture, transfection, imaging) * Neuroscience (in vivo experiments ...
Lab and Research Technician 2, Pharmacology
Charlottesville, VA · On-site
$40K - $50K/yr
Perform standard molecular biology (transformation, plasmid preparation, mutagenesis, and sub-cloning). * Learn/implement cell culture approaches for preparation of viral constructs. * Perform a ...
Lab and Research Technician 2, Pharmacology
Charlottesville, VA · On-site
$40K - $50K/yr
Perform standard molecular biology (transformation, plasmid preparation, mutagenesis, and sub-cloning). * Learn/implement cell culture approaches for preparation of viral constructs. * Perform a ...
Research Asst - Grad Student
Lubbock, TX · On-site
$20K - $25K/yr
Probe the mechanism of P-glycoprotein, a protein involved in the multidrug-resistance of cancers and involves site- directed mutagenesis, yeast transformations, drug resistance assays, membrane ...
Research Asst - Grad Student
Lubbock, TX · On-site
$20K - $25K/yr
Probe the mechanism of P-glycoprotein, a protein involved in the multidrug-resistance of cancers and involves site- directed mutagenesis, yeast transformations, drug resistance assays, membrane ...
Scientist I, Biotherapeutics
Bedford, MA · On-site
$90K - $115K/yr
Working knowledge of emerging and established protein engineering technologies such as AI/ML-based protein optimization, structure-based rational mutagenesis, or combinatorial display-based ...
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Scientist I, Biotherapeutics
Bedford, MA · On-site
$90K - $115K/yr
Working knowledge of emerging and established protein engineering technologies such as AI/ML-based protein optimization, structure-based rational mutagenesis, or combinatorial display-based ...
Conduct molecular biology workflows, including cloning, mutagenesis, and plasmid preparation. Perform protein expression and purification using insect or mammalian systems. * Cell Culture Management:
Conduct molecular biology workflows, including cloning, mutagenesis, and plasmid preparation. Perform protein expression and purification using insect or mammalian systems. * Cell Culture Management:
Experience in Molecular Biology techniques: oligo design, PCR, mutagenesis, diverse cloning experience, data analysis, in vitro transcription and RNA production required * Experience in protein ...
Experience in Molecular Biology techniques: oligo design, PCR, mutagenesis, diverse cloning experience, data analysis, in vitro transcription and RNA production required * Experience in protein ...
Staff Research Assistant 1 - 140541
San Diego, CA · On-site
$30.12 - $32.10/hr
... CRISPR mutagenesis, in situ hybridizations, protein purification, immunofluorescence, and microinjection. * Proven ability to express and purify proteins using affinity and conventional ...
Staff Research Assistant 1 - 140541
San Diego, CA · On-site
$30.12 - $32.10/hr
... CRISPR mutagenesis, in situ hybridizations, protein purification, immunofluorescence, and microinjection. * Proven ability to express and purify proteins using affinity and conventional ...
RTP Research Fellow-LS-Dr Kun Ling-BMB
Rochester, MN · On-site
$49K - $67K/yr
Common molecular and cellular techniques are required, including molecular cloning, mutagenesis, cell culture and transfection, and immunoblotting. Experience on recombinant protein expression and ...
RTP Research Fellow-LS-Dr Kun Ling-BMB
Rochester, MN · On-site
$49K - $67K/yr
Common molecular and cellular techniques are required, including molecular cloning, mutagenesis, cell culture and transfection, and immunoblotting. Experience on recombinant protein expression and ...
Proficiency with core molecular biology techniques: vector engineering, cloning and mutagenesis, qRT-PCR, ELISA, MSD, Western blotting, next-generation sequencing platforms, and flow cytometry (FACS)
Proficiency with core molecular biology techniques: vector engineering, cloning and mutagenesis, qRT-PCR, ELISA, MSD, Western blotting, next-generation sequencing platforms, and flow cytometry (FACS)
In-depth knowledge of protein structure-function principles and structure-guided mutagenesis. * Prior experience with protein engineering applications to improve protein properties, such as activity ...
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In-depth knowledge of protein structure-function principles and structure-guided mutagenesis. * Prior experience with protein engineering applications to improve protein properties, such as activity ...
Whole genome transposon mutagenesis Additional responsibilities include: * Maintaining rigorous sample tracking and organization across numerous parallel workflows * Leading and meticulously ...
Whole genome transposon mutagenesis Additional responsibilities include: * Maintaining rigorous sample tracking and organization across numerous parallel workflows * Leading and meticulously ...
In-depth knowledge of protein structure-function principles and structure-guided mutagenesis. * Prior experience with protein engineering applications to improve protein properties, such as activity ...
In-depth knowledge of protein structure-function principles and structure-guided mutagenesis. * Prior experience with protein engineering applications to improve protein properties, such as activity ...
Research Engineering/Scientist Associate III
Austin, TX · On-site
$55K/yr
Preferred Qualifications Previous experience with cloning, mutagenesis, and protein expression. Salary Range $55,000 + DOE Working Conditions * Uniforms and/or personal protection equipment ...
Research Engineering/Scientist Associate III
Austin, TX · On-site
$55K/yr
Preferred Qualifications Previous experience with cloning, mutagenesis, and protein expression. Salary Range $55,000 + DOE Working Conditions * Uniforms and/or personal protection equipment ...
Design and perform molecular biology experiments, including plasmid construction, cloning, and mutagenesis. Generate and characterize CRISPR-edited cell lines for functional studies. Express and ...
Design and perform molecular biology experiments, including plasmid construction, cloning, and mutagenesis. Generate and characterize CRISPR-edited cell lines for functional studies. Express and ...
Research Assistant II - GI Medical Oncology
Houston, TX · On-site
$56K - $68K/yr
Execute recombinant DNA cloning procedures, including transformation and mutagenesis. Generate knockout cell lines for research studies. Utilize antibodies in immunostaining applications. Perform ...
New
Research Assistant II - GI Medical Oncology
Houston, TX · On-site
$56K - $68K/yr
Execute recombinant DNA cloning procedures, including transformation and mutagenesis. Generate knockout cell lines for research studies. Utilize antibodies in immunostaining applications. Perform ...
New
Proficiency with core molecular biology techniques: vector engineering, cloning and mutagenesis, qRT-PCR, ELISA, MSD, Western blotting, next-generation sequencing platforms, and flow cytometry (FACS)
Proficiency with core molecular biology techniques: vector engineering, cloning and mutagenesis, qRT-PCR, ELISA, MSD, Western blotting, next-generation sequencing platforms, and flow cytometry (FACS)
RESEARCH ASSISTANT IV- Mosnier Lab
San Diego, CA · On-site
$75K - $90K/yr
Perform protein engineering work, including construct design, site-directed mutagenesis, expression vector development, and protein expression/purification strategies. * Maintain and manipulate ...
RESEARCH ASSISTANT IV- Mosnier Lab
San Diego, CA · On-site
$75K - $90K/yr
Perform protein engineering work, including construct design, site-directed mutagenesis, expression vector development, and protein expression/purification strategies. * Maintain and manipulate ...
Mutagenesis information
What jobs in the US pay 300,000 a year?
In the field of mutagenesis and related biomedical research, senior roles such as principal scientists, research directors, or biotech executives can reach or exceed a $300,000 annual salary, especially with extensive experience, advanced degrees, and leadership responsibilities. High-paying positions often require specialized skills in molecular biology, genetics, or laboratory management, and may involve working in biotech or pharmaceutical companies. Salary levels vary based on location, company size, and individual expertise.
What are the key skills and qualifications needed to thrive as a Mutagenesis Scientist, and why are they important?
To thrive as a Mutagenesis Scientist, you need a strong background in molecular biology, genetics, and laboratory techniques, typically supported by an advanced degree in biological sciences. Experience with CRISPR, site-directed mutagenesis kits, PCR, and DNA sequencing platforms is essential. Attention to detail, critical thinking, and effective teamwork are valuable soft skills in this role. These skills ensure accurate genetic modifications, reliable experimental results, and successful collaboration on research projects.
What biology jobs pay over $100k?
In the field of mutagenesis and related biology roles, positions such as senior research scientist, molecular biologist, and biotech project manager often have salaries exceeding $100,000 annually. These roles typically require advanced degrees, specialized skills in genetic analysis, and experience with laboratory techniques or bioinformatics tools.
What is the difference between Mutagenesis vs Genetic Engineer?
| Aspect | Mutagenesis | Genetic Engineer |
|---|---|---|
| Required Credentials | Laboratory skills, knowledge of molecular biology, often a bachelor's or master's degree | Advanced degrees (Master's or PhD), expertise in genetic modification techniques |
| Work Environment | Research labs, biotech companies, pharmaceutical labs | Research institutions, biotech firms, pharmaceutical companies |
| Industry Usage | Used for creating genetic variations, studying mutations | Designing and implementing genetic modifications in organisms |
| Common Search/Comparison | Mutagenesis vs Genetic Engineer |
Mutagenesis involves inducing mutations to study gene functions or create genetic diversity, often using chemical or physical agents. Genetic engineers design and implement specific genetic modifications using advanced techniques like CRISPR. While mutagenesis is more about random mutation induction, genetic engineering focuses on precise gene editing. Both roles are essential in biotechnology and share overlapping skills, but differ in complexity and purpose.
What are some typical challenges faced by scientists working in mutagenesis, and how can they be addressed?
Scientists specializing in mutagenesis often encounter challenges such as ensuring the specificity of induced mutations and accurately screening for desired genetic changes. Maintaining the viability of organisms while introducing mutations and avoiding off-target effects are also common concerns. These issues can be addressed by carefully selecting mutagenic agents, optimizing experimental protocols, and using advanced screening techniques such as next-generation sequencing. Collaboration with bioinformatics specialists and molecular biologists is also essential to interpret results and refine approaches.
What is the highest paying job in genetics?
In genetics, roles such as genetic counselors, research directors, and senior molecular geneticists tend to have the highest salaries, often exceeding six figures annually. Positions requiring advanced degrees, specialized skills, and leadership responsibilities typically offer the highest compensation in the field.
What are the applications of mutagenesis?
Mutagenesis is used in research and biotechnology to study gene functions, develop genetically modified organisms, and create proteins with new or improved properties. It is commonly applied in fields like medicine, agriculture, and pharmaceuticals to enhance crop traits, produce therapeutic proteins, and understand genetic diseases. Laboratory techniques such as site-directed mutagenesis and chemical mutagenesis are essential tools for these applications.
What is mutagenesis?
Mutagenesis is a process by which the genetic information of an organism is changed in a stable manner, resulting in a mutation. This can occur naturally or be induced artificially in a laboratory, often using chemicals, radiation, or genetic engineering techniques. Scientists use mutagenesis to study gene function, create genetic diversity, or develop organisms with desirable traits. In research, mutagenesis helps identify the roles of specific genes and understand the effects of genetic changes.
More about Mutagenesis jobs
What job categories do people searching Mutagenesis jobs look for? The top searched job categories for Mutagenesis jobs are:
Duke University rating
6.7
Based on 55 frontline employees who took The Breakroom Quiz
442nd of 560 rated colleges and universities
Job description
School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.
Essential Physical Job Functions:
Be You.
The Tarrant and Hershfield labs are seeking a motivated and skilled structural biochemist to join our team in the study of immunodeficiency diseases, inborn errors of immunity, and purine metabolism. The ideal candidate has a strong foundation in structural biology and protein engineering, with practical laboratory experience in recombinant protein expression, purification, and characterization.
Minimum Requirements:
- Education: PhD in Structural Biochemistry with experience in protein engineering, purification of challenging targets, design and mutagenesis
- The appointee must have greater than 5 years of postdoctoral training.
Preferred Qualifications:
- Ability to produce tagged and isotopically labelled proteins
- Proficiency in ion exchange chromatography, size exclusion chromatography (SEC), and HPLC
- Strong analytical and problem-solving skills
- Ability to work independently and as part of a collaborative team
- Effective written and verbal communication skills.
Other Requirements:
- Hands-on experience with one or more structural biology techniques: NMR spectroscopy, X-ray crystallography, mass spectrometry
- Experience conducting protein-protein interaction studies and biochemical/biophysical characterization
This position is (insert options below).
- Onsite. The work is performed on-site or at a designated assignment location.
Be Bold.
- Design and execute experiments to investigate the molecular mechanisms underlying immunodeficiency diseases and purine metabolism, specifically adenosine deaminase 2.
- Analyze and interpret experimental data.
- Prepare manuscripts for publication in peer-reviewed journals.
- Present research findings at scientific conferences.
Choose Duke.
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions:
Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
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About Duke University
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Duke is regarded as one of America's leading research universities. Located in Durham, North Carolina, Duke is positioned in the heart of the Research Triangle, which is ranked annually as one of the best places in the country to work and live. Duke has more than 15,000 students who study and conduct research in its 10 undergraduate, graduate, and professional schools. With about 40,000 employees, Duke is the third largest private employer in North Carolina, and it now has international programs in more than 150 countries.
Industry
Colleges, universities, and professional schools and hospitals
Company size
10,000+ Employees
Headquarters location
Durham, NC, US