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Mutagenesis Jobs (NOW HIRING)

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Scientist II

South San Francisco, CA · On-site

Cloning and mutagenesis * Independently design and execute well-controlled experiments * Collect, analyze, interpret, and effectively communicate data * Collaborate across research groups to support ...

Uw

Research Scientist/Engr 1

Seattle, WA · On-site

$58K/yr

PCR, Gibson/Golden Gate assembly, mutagenesis, bacterial transformation, plasmid preparation, and sequence verification. Protein production: bacterial expression, affinity purification ...

DSM

Scientist, GPCR Biology - San Diego, CA

San Diego, CA · On-site

$10K - $140K/yr

Strong molecular biology (cloning, transfection, construct design, mutagenesis) and mammalian cell culture skills, with a track record of building reliable cell-based assays. * Expertise with taste ...

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Mutagenesis information

What are the key skills and qualifications needed to thrive as a mutagenesis scientist, and why are they important?

To thrive as a Mutagenesis Scientist, you need a strong background in molecular biology, genetics, and laboratory techniques, typically supported by an advanced degree in biological sciences. Experience with CRISPR, site-directed mutagenesis kits, PCR, and DNA sequencing platforms is essential. Attention to detail, critical thinking, and effective teamwork are valuable soft skills in this role. These skills ensure accurate genetic modifications, reliable experimental results, and successful collaboration on research projects.

What is the difference between Mutagenesis vs Genetic Engineer?

AspectMutagenesisGenetic Engineer
Required CredentialsLaboratory skills, knowledge of molecular biology, often a bachelor's or master's degreeAdvanced degrees (Master's or PhD), expertise in genetic modification techniques
Work EnvironmentResearch labs, biotech companies, pharmaceutical labsResearch institutions, biotech firms, pharmaceutical companies
Industry UsageUsed for creating genetic variations, studying mutationsDesigning and implementing genetic modifications in organisms
Common Search/ComparisonMutagenesis vs Genetic Engineer

Mutagenesis involves inducing mutations to study gene functions or create genetic diversity, often using chemical or physical agents. Genetic engineers design and implement specific genetic modifications using advanced techniques like CRISPR. While mutagenesis is more about random mutation induction, genetic engineering focuses on precise gene editing. Both roles are essential in biotechnology and share overlapping skills, but differ in complexity and purpose.

What are some typical challenges faced by scientists working in mutagenesis, and how can they be addressed?

Scientists specializing in mutagenesis often encounter challenges such as ensuring the specificity of induced mutations and accurately screening for desired genetic changes. Maintaining the viability of organisms while introducing mutations and avoiding off-target effects are also common concerns. These issues can be addressed by carefully selecting mutagenic agents, optimizing experimental protocols, and using advanced screening techniques such as next-generation sequencing. Collaboration with bioinformatics specialists and molecular biologists is also essential to interpret results and refine approaches.

What is mutagenesis?

Mutagenesis is a process by which the genetic information of an organism is changed in a stable manner, resulting in a mutation. This can occur naturally or be induced artificially in a laboratory, often using chemicals, radiation, or genetic engineering techniques. Scientists use mutagenesis to study gene function, create genetic diversity, or develop organisms with desirable traits. In research, mutagenesis helps identify the roles of specific genes and understand the effects of genetic changes.
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Infographic showing various Mutagenesis job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

POSTDOCTORAL RESEARCHER - McDermott Center HG&D - Seplyarskiy Lab

University Of Texas Southwestern Medical Cent (The

Dallas, TX • On-site

$114K/yr

Full-time

Medical, Retirement, PTO

Re-posted 10 days ago

UT Southwestern rating

7.9

Company rating: 7.9 out of 10

Based on 152 frontline employees who took The Breakroom Quiz

108th of 887 rated healthcare providers

Job description

Postdoctoral Researcher in Mutagenesis, Population and Statistical Genetics

A postdoctoral training opportunity is now available in the Seplyarskiy Lab in the McDermott Center for Human Growth and Development at UT Southwestern Medical Center at Dallas. We are currently accepting applications for a postdoctoral fellowship in mutagenesis, statistical genomics, and computational biology.

Research directions

  • Mutagenesis: evolution of mutational mechanisms across the tree of life; somatic mutagenesis and clonal dynamics; reconstruction of early developmental lineages from mosaic mutations.
  • Population genetics: quantifying recurrence and number of mutational origins in large cohorts; discovery of strongly selected sites and constraint from recurrence-aware models.
  • Statistical genetics: partitioning heritability and enrichment in DNA-repair and mutagenesis pathways (including cancer-relevant contexts); development of mutation rate model

Training & environment

  • Close mentorship in mutagenesis, population genetics, and statistical genetics
  • Active joint journal clubs with external groups (Ziyue Gao - UPenn, Evan Koch - Yale), collaborative community at UTSW's McDermott Center.
  • Access to large datasets (e.g., biobanks, gnomAD-class resources) and compute.

Responsibilities

  • Formulate and test new quantitative models of mutation, selection, and clonal evolution.
  • Develop methods tailored to large-scale genomic datasets.
  • Lead analyses, interpret results and drive manuscripts to completion.
  • Collaborate on related work across the lab's projects.

Ph.D. (or equivalent, or soon to be completed) in Statistics, Biostatistics, Computer Science, Population/Statistical Genetics, Bioinformatics/Computational Biology

Proficiency in R and/or Python/ or other languages

Plus factors: experience with method development, exposure to population-genetic theory (selection, demography, coalescent/ARG), mutational-process modeling, scalable data engineering, cloud/HPC, or ancient DNA.

Interested individuals should send a CV, cover letter briefly describing previous research experience, and a summary of current research interests.

UTSouthwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Asan equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis ofrace, color, religion, national origin, sex,sexual orientation, gender identity, gender expression,age, disability, genetic information, citizenship status, or veteran status.

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.

To learn more about the benefits UT Southwestern offers, visithttps://www.utsouthwestern.edu/employees/hr-resources/

Benefits
    UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
    • PPO medical plan, available day one at no cost for full-time employee-only coverage
    • 100% coverage for preventive healthcare - no copay
    • Paid Time Off, available day one
    • Retirement Programs through the Teacher Retirement System of Texas (TRS)
    • Paid Parental Leave Benefit
    • Wellness programs
    • Tuition Reimbursement
    • Public Service Loan Forgiveness (PSLF) Qualified Employer
    • Learn more about these and other UTSW employee benefits!

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