Msc Animal Jobs (NOW HIRING)

Company Overview:
CORE Biomedicine Inc. is a pioneering biotech startup dedicated to advancing novel therapies in oncology. We specialize in the development of small molecule drugs targeting novel pathways for the treatment of various cancers.

Position Overview:
We are seeking a dynamic and experienced individual, with strong multitasking skills to support our ongoing drug discovery and development programs. The person will lead PK/ADME/Clin Pharm for the various CORE oncology programs at various stages.

Key Responsibilities:

• Work with our internal/external teams (CROs) to support various PK/ADME needs for discovery programs, including:
  • Design suitable PK studies for ongoing discovery programs to advance from Hit-to-lead and lead optimization
  • Decipher ADME and metabolism profile to help medicinal chemistry to design and advance ongoing programs at various stages
  • Help to characterize lead candidates with preferred PK/ADME profile based on their chemical and pharmacology properties
  • Use various animal PK/PD data and modeling, to project potential clinical dose range and translational strategy
• Collaborate closely with medicinal chemistry, biology, pharmacology and toxicology for IND enabling studies and regulatory submissions
• Work with our teams, especially our clinical team, for various clinical needs
• Maintain high standards of data quality, documentation, and scientific rigor

Qualifications:

• PhD in Pharmacokinetics, Pharmaceutical Sciences, Medicinal Chemistry, Analytical Chemistry, or related discipline with 3+ years of relevant industry experience, or MSc with 5+ years of pharmaceutical and biotechnology experience
• Strong foundation in DMPK, ADME, and pharmacokinetics for small-molecule drug discovery, development and clinical
• Experience designing and interpreting in vivo PK/ADME studies, as well drug metabolism profile
• Familiarity with PK/PD modeling tools (e.g., Phoenix, MATLAB, R) is a plus
• Experience working with CROs and managing outsourced studies
• Excellent data analysis, problem-solving, and communication skills
• Comfortable operating in a fast-paced, highly collaborative startup environment
• Self-motivated, adaptable, and eager to take ownership of projects
• Competitive compensation
• Paid time off (vacation, holidays, and sick leave)
• Flexible work arrangements (hybrid or remote options where applicable)
• 401k, Bonus, Equity, Healthcare (Medical, Dental, Vision)
• Opportunity to work at the forefront of cancer research in a mission-driven startup environment