This interdisciplinary program develops advanced in vitro models of hematopoietic and immune system function such as conducting research at the intersection of microphysiological systems (Organs-on ...
Quick apply
This interdisciplinary program develops advanced in vitro models of hematopoietic and immune system function such as conducting research at the intersection of microphysiological systems (Organs-on ...
... microphysiological systems, tissue engineering, and regenerative medicine. We are seeking candidates who can expand our research program to include the application of knowledge from these different ...
... microphysiological systems, tissue engineering, and regenerative medicine. We are seeking candidates who can expand our research program to include the application of knowledge from these different ...
... microphysiological systems, tissue engineering, and regenerative medicine. We are seeking candidates who can expand our research program to include the application of knowledge from these different ...
... microphysiological systems, tissue engineering, and regenerative medicine. We are seeking candidates who can expand our research program to include the application of knowledge from these different ...
Microphysiological information
What are the key skills and qualifications needed to thrive as a microphysiological systems scientist, and why are they important?
To thrive as a Microphysiological Systems Scientist, you need a strong background in cell biology, tissue engineering, and biomaterials, typically supported by an advanced degree in biological sciences or bioengineering. Familiarity with microfluidic device fabrication, imaging systems, and analytical software like MATLAB or ImageJ is often required. Creative problem-solving, attention to detail, and strong collaboration skills are crucial in this interdisciplinary field. These skills enable the design and analysis of complex biological models that advance drug discovery and biomedical research.
What is a microphysiological system?
Microphysiological systems, also known as organ-on-a-chip technologies, are advanced laboratory models that replicate the functions of human organs on a miniature scale. These systems use living cells arranged on micro-engineered platforms to mimic the structure and function of tissues and organs. They are used in biomedical research to study disease mechanisms, drug responses, and toxicity in a controlled environment, potentially reducing the need for animal testing. Microphysiological systems provide more accurate and human-relevant data compared to traditional cell cultures or animal models.
What is the difference between Microphysiological vs Cell Culture Technician?
| Aspect | Microphysiological | Cell Culture Technician |
|---|---|---|
| Required Credentials | Typically requires a degree in biology, biomedical engineering, or related fields | Often requires a degree or certification in biology or laboratory techniques |
| Work Environment | Research labs, biotech companies, pharmaceutical testing facilities | Laboratories, research institutions, biotech companies |
| Industry Usage | Used in drug testing, disease modeling, tissue engineering | Used in cell growth, maintenance, and preparation for experiments |
Microphysiological roles focus on creating complex tissue models that mimic human organs, often requiring advanced technical skills. Cell Culture Technicians primarily handle cell growth and maintenance. While both roles involve laboratory work and biological expertise, Microphysiological positions typically demand more specialized knowledge in tissue engineering and organ-on-chip systems.
What are common challenges faced by microphysiological system researchers, and how can new team members prepare for them?
Microphysiological system researchers often encounter challenges such as integrating complex biological and engineering concepts, troubleshooting device malfunctions, and ensuring reproducibility of experimental results. New team members can prepare by staying updated on the latest advances in organ-on-chip technologies, refining their problem-solving skills, and actively communicating with multidisciplinary colleagues. Participating in regular team meetings and collaborating closely with engineers, biologists, and data analysts will help address issues as they arise and foster a supportive research environment.
What are popular job titles related to Microphysiological jobs in Pennsylvania? For Microphysiological jobs in Pennsylvania, the most frequently searched job titles are:
What job categories do people searching Microphysiological jobs in Pennsylvania look for? The top searched job categories for Microphysiological jobs in Pennsylvania are:
Postdoctoral Associate Human Hepatic Models and Metabolism Studies
Pittsburgh, PA • On-site
Full-time
Re-posted 17 days ago
Job description
Title: Postdoctoral Associate, Human Hepatic Models and Metabolism Studies Location: Onsite, Pittsburgh, PA 15213 Type: Direct-Hire/Permanent Hours: Standard business hours Start: May Overview: We are looking for a highly motivated Postdoctoral Associate to join a lab focused on discovering novel therapeutics. This interdisciplinary program develops advanced in vitro models of hematopoietic and immune system function such as conducting research at the intersection of microphysiological systems (Organs-on-Chips) and immunology. The role emphasizes modeling hematopoietic stem and progenitor cell biology and immune cell development in relevant microenvironments while integrating immune readouts with multi-system platforms to study host responses and therapeutic modulation. Responsibilities:
- Design and conduct experimental studies investigating hematopoietic stem and progenitor cell biology and immune cell development using advanced in vitro systems
- Establish and maintain multicellular cultures incorporating hematopoietic, stromal, and vascular components
- Perform and optimize assays to characterize immune cell populations, differentiation trajectories, and functional responses
- Apply quantitative techniques including flow cytometry, molecular assays, and functional immune assays to analyze experimental outcomes
- Contribute to development and refinement of experimental workflows to enhance reproducibility and robustness
- Collaborate with multidisciplinary teams to integrate immune-related findings with complementary biological and engineering systems
- Maintain accurate and detailed documentation of experimental procedures and results
- Analyze and interpret data, and contribute to preparation of manuscripts, reports, and grant applications
- Mentor trainees and assist in training of laboratory personnel as needed
Requirements:
- Ph.D. in Immunology, Hematology, Stem Cell Biology, Biomedical Engineering, or a related field
- Experience working with hematopoietic stem and progenitor cells and/or immune cell populations
- Strong background in cell culture and immune characterization techniques
- Demonstrated ability to design and execute complex biological experiments
- Ability to work independently and collaboratively in a multidisciplinary research environment
- Strong written and verbal communication skills
Preferred:
- Experience with in vitro hematopoietic or immune system models, including Organs-on-Chips
- Familiarity with flow cytometry, immunophenotyping, and multiparametric data analysis
- Experience with functional immune assays or host-response studies
- Experience working in interdisciplinary teams integrating biology and engineering
#M3 Ref: #558-Scientific