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Microphysiological Systems Jobs (NOW HIRING)

Cape Fox SS

Biomarker Technician

Frederick, MD · On-site

$69K - $75K/yr

Job Summary The Employee shall provide laboratory support by performing work on microphysiological systems (MPS), next generation sequencing, real time PCR, Nanostring, Luminex multiplexed ...

e184

Senior Scientist - Placenta Biology

Portland, OR · On-site

$97K - $132K/yr

Familiarity with perfusion or microphysiological culture platforms * Experience translating in vivo biological findings into engineered or experimental systems * Prior startup or early-stage ...

University of Michigan

RESEARCH FELLOW

Ann Arbor, MI · On-site

... microphysiological models, scRNAseq, and rodent models of disease. The selected candidate will ... Fabricate and characterize biomaterial drug delivery systems targeting immune function. * Molecular ...

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$36K

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$116K

How much do microphysiological systems jobs pay per year?

As of Jun 7, 2026, the average yearly pay for microphysiological systems in the United States is $68,438.00, according to ZipRecruiter salary data. Most workers in this role earn between $43,500.00 and $85,000.00 per year, depending on experience, location, and employer.

What types of interdisciplinary collaboration are common in Microphysiological Systems roles?

Professionals working in Microphysiological Systems often collaborate closely with experts from various fields, including bioengineering, pharmacology, toxicology, and computational modeling. You can expect to work on multidisciplinary teams to design experiments, analyze data, and interpret results, as well as coordinate with external partners such as pharmaceutical companies or academic institutions. This collaborative environment not only broadens your scientific perspective but also enhances communication and project management skills, which are highly valued for career progression in this rapidly evolving field.

What are Microphysiological Systems?

Microphysiological Systems (MPS), also known as organ-on-a-chip technology, are advanced cell culture platforms that mimic the structure and function of human tissues and organs at a miniature scale. These systems use microengineering techniques to create environments where human cells can grow and interact in a way that closely resembles how they behave in the body. MPS are widely used in biomedical research, drug development, and toxicity testing as they provide more accurate and human-relevant data compared to traditional cell culture or animal models. By recreating organ-level functions, MPS help scientists study diseases, predict drug responses, and reduce the need for animal testing.

What is the difference between Microphysiological Systems vs Tissue Engineer?

AspectMicrophysiological SystemsTissue Engineer
Required credentialsTypically requires a degree in biomedical engineering, biology, or related fields; advanced degrees preferredRequires a degree in biomedical engineering, tissue engineering, or related disciplines; often with lab experience
Work environmentResearch labs, biotech companies, or academic institutions focusing on organ-on-chip and in vitro modelsLaboratories, biotech firms, or research centers working on tissue fabrication and regenerative medicine
Industry usageUsed in drug testing, disease modeling, and personalized medicineUsed in regenerative medicine, implant development, and tissue replacement therapies

While both roles involve biomedical research, Microphysiological Systems specialists focus on developing organ-on-chip models for testing and research, whereas Tissue Engineers design and create biological tissues for medical applications. Both careers require similar educational backgrounds but serve different purposes within the biomedical industry.

What are the key skills and qualifications needed to thrive as a Microphysiological Systems Scientist, and why are they important?

To thrive as a Microphysiological Systems Scientist, you need a strong background in cell biology, bioengineering, and tissue culture, typically supported by an advanced degree in a life science or engineering field. Expertise with microfluidic devices, 3D cell culture platforms, and analytical tools like microscopy and molecular assays is commonly required. Strong problem-solving skills, meticulous attention to detail, and effective collaboration make candidates excel in this role. These skills and qualities are crucial for developing reliable organ-on-chip models that advance drug discovery and biomedical research.
Infographic showing various Microphysiological Systems job openings in the United States as of May 2026, with employment types broken down into 100% As Needed. Highlights an 27% Hybrid, and 73% Remote job distribution, with an average salary of $68,438 per year, or $32.9 per hour.
Director, Advanced Cell Model External Engagement, Safety Sciences

Director, Advanced Cell Model External Engagement, Safety Sciences

AstraZeneca

Gaithersburg, MD • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 19 days ago

AstraZeneca rating

8.6

Company rating: 8.6 out of 10

Based on 43 frontline employees who took The Breakroom Quiz

16th of 71 rated pharmaceutical

Job description

At AstraZeneca, we push the boundaries of science to deliver life-changing medicines. Our global Safety Sciencesorganizationdelivers innovative non-clinical safety science and toxicologyexpertiseto enable the discovery,developmentand registration of novel medicinesacross drug modalities and therapeutic areas.

As a science-driven business, we continuously strive to innovate to enhance our scientific capabilitiesandaccelerate the speed at which we bring medicines forward.

Advanced Cell Models (ACM), such as organoids and Microphysiological Systems (MPS), are New Approach Methods (NAMs) used for safety assessment and to study disease biology. We are playing a leading role in the field to apply ACM to drug discovery and development, in particular to predict and optimize therapeutic index for novel candidate drugs.

To enhance our ACM strategy, we are looking to recruit a Director, Advanced Cell Model External Engagement, Safety Sciences. The role will be based at our R&D site in Gaithersburg, MD. It is part of the Advanced Cell Models Team and reports to the Senior Director, Head of Advanced Cell Models, Safety Sciences.

  • Develop andalign on anAdvanced Cell Model(ACM)strategic plan aligned withglobal regulatoryroadmaps/guidanceand policyon NAMs andAZ 3Rs.
  • Workwith internal stakeholders and external consortia and health authorities to qualify,validateand gain acceptance of NAMsin accordance with, for example,regulatory roadmaps/guidance and policy on NAMs.
  • Lead influencethrough relevant externalstakeholders and consortiaontheacceptance ofNAMsdatain regulatory submissions.
  • ForACMsubmissions contribute to and align AZ methods withstandardizationroadmapsultimately submittingand securing acceptance of relevant ISO applications.The individual will lead efforts to promoterigorin ACMs and devise frameworks forprioritizingACM standards and qualification both internally and for health authority acceptance.
  • Impact onAZR&D globally byadvisingothers,including senior management,ondevelopments and updates in regulatory guidance and policy for NAMs globally.
  • Responsible forstrengtheningAstraZeneca's external reputation and leadership in ACM and NAMs through active participation with industry and health authority consortia.
  • ImpactonR&D globallyby leadingcross-enterprisepartnerships with innovation leaders tofacilitatethe sharing of ideas tooptimizetheapplication ofACMaligned to the3Rs, providing expert technical direction and problem solving.

Minimum Qualifications:

  • 7 -10 years of relevant postdoctoral experience.

  • Strong academic background with PhD in a relevant field (Cell Biology, Engineering, Pharmacology,Toxicologyor related discipline), with high quality publications.

  • Excellent understanding of ACM and NAMs (including organoids, MPS, in silico modelling), 3Rs and regulatory requirements for drug development.

  • A proven understanding of drug discovery and development, with a strongtrack recordof independent research in industry, biotech, or academic setting.

  • Track recordof scientific innovation, leadingdevelopmentand application ofcutting-edge, novel science.

  • A collaborative, team-oriented approach, able to solve problems in a goal-focused fashion withcapacityto coordinate tasks across multiple projects.

  • Excellentinfluencing,communication and presentation skills, ability to work across scientific disciplines and bridge organizational boundaries.

Why AstraZeneca?

At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We're on an exciting journey to pioneer the future of healthcare.

So, what's next?

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!

The annual base pay (or hourly rate of compensation) for this position ranges from $184,538.40 - $276,807.60 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

18-May-2026

Closing Date

31-May-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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