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Microfluidic Engineer Jobs in California (NOW HIRING)

Bio-Techne

Staff Mechanical Engineer

San Jose, CA · On-site

$152K - $250K/yr

This position will report to the Mechanical Engineering Hardware Manager while working with a group ... Experience in capillary and/or microfluidic based design. * Experience with opto-mechanical ...

Bio-Techne

Staff Mechanical Engineer

San Jose, CA

$152K - $250K/yr

This position will report to the Mechanical Engineering Hardware Manager while working with a group ... Experience in capillary and/or microfluidic based design. * Experience with opto-mechanical ...

OmniAb

Field Engineer, xPloration

Emeryville, CA · On-site

$103K - $115K/yr

About This Role We're seeking a Field Engineer to support testing, QC, and field maintenance of ... Experience supporting high-throughput screening, single-cell, microfluidic, or imaging platforms in ...

OmniAb

Field Engineer, xPloration

Emeryville, CA · On-site

$103K - $115K/yr

About This Role We're seeking a Field Engineer to support testing, QC, and field maintenance of ... Experience supporting high-throughput screening, single-cell, microfluidic, or imaging platforms in ...

Pharmaceutical Company

Scientist

San Diego, CA

Utilize microfluidic or T-junction mixing for LNP formulation * Perform surface conjugation for ... MS + 2 years or BS + 5 years in Chemistry, Chemical Engineering, Bioengineering, Pharmaceutical ...

Roche

Senior Systems Engineer

Santa Clara, CA

$122K - $167K/yr

We are seeking a passionate Senior Systems Engineer to join our Systems Development Group to ... You have experience in implementing workflow on semiconductor-based sensing devices or microfluidic ...

ATS Automation

Director of Engineering

Irvine, CA · On-site

The Director of Engineering leads and develops a multidisciplinary engineering organization ... Experience with microfluidic and low volume dispensing * Proven ability to scale teams and ...

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Showing results 1-20

All JobsMicrofluidic Engineer JobsMicrofluidic Engineer Jobs in California

Microfluidic Engineer information

See California salary details

$44.9K

$101.5K

$164.3K

How much do microfluidic engineer jobs pay per year?

As of Jun 14, 2026, the average yearly pay for microfluidic engineer in California is $101,531.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,400.00 and $124,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Microfluidic Engineer position, and why are they important?

To thrive as a Microfluidic Engineer, you need a solid background in engineering, physics, or biomedical sciences, with expertise in fluid dynamics, microfabrication, and device prototyping. Familiarity with CAD software, cleanroom processes, simulation tools like COMSOL Multiphysics, and often a relevant certification or advanced degree are commonly valued. Strong analytical thinking, problem-solving, and collaboration skills are crucial, as projects frequently involve interdisciplinary teams. These competencies are important for successfully designing, developing, and troubleshooting innovative microfluidic devices used in fields like life sciences, diagnostics, and research.

What are typical daily responsibilities for a Microfluidic Engineer?

A Microfluidic Engineer's daily responsibilities often include designing and simulating microfluidic systems, conducting laboratory experiments, analyzing prototype performance, and working closely with biologists, chemists, and other engineers to refine project requirements. They may also spend time fabricating devices in cleanroom environments, documenting results, and troubleshooting technical challenges that arise during development. Collaboration with team members and stakeholders is common, as is the need to stay up-to-date on advancements in fabrication techniques and materials. These activities ensure that innovative and reliable microfluidic solutions are created for applications ranging from medical diagnostics to drug development.

What is a Microfluidic Engineer job?

A Microfluidic Engineer designs, develops, and optimizes microfluidic systems for applications in biotechnology, healthcare, diagnostics, and research. They work with small-scale fluid dynamics, creating devices that manipulate tiny volumes of liquids for tasks like lab-on-a-chip technology, drug delivery, and chemical analysis. Their role involves material selection, prototyping, testing, and integrating microfluidic systems with sensors and electronics. They often collaborate with biologists, chemists, and engineers to develop innovative solutions for scientific and industrial challenges.

What are popular job titles related to Microfluidic Engineer jobs in California? For Microfluidic Engineer jobs in California, the most frequently searched job titles are:
What job categories do people searching Microfluidic Engineer jobs in California look for? The top searched job categories for Microfluidic Engineer jobs in California are:
What cities in California are hiring for Microfluidic Engineer jobs? Cities in California with the most Microfluidic Engineer job openings:
Microfluidic Engineer jobs near you
Infographic showing various Microfluidic Engineer job openings in California as of June 2026, with employment types broken down into 100% Part Time. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $101,531 per year, or $48.8 per hour.
Sr. Mechanical Design Engineer

Sr. Mechanical Design Engineer

RheoSense, Inc.

San Ramon, CA • On-site

$120K - $155K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

This job post has expired 2 days ago. Applications are no longer accepted.

Job description

About RheoSense, Inc.
RheoSense, Inc. (RheoSense) is a leading scientific instrumentation company specializing in high-precision microfluidic viscosity measurement technology. Our innovative VROC® platform is trusted by researchers, engineers, and scientists across biotechnology, pharmaceuticals, materials science, and advanced manufacturing.
We are committed to delivering accurate, reliable, and user-friendly measurement solutions that empower our customers to accelerate discovery, improve product performance, and drive scientific advancement.
At RheoSense, we foster a collaborative, fast-moving environment where innovation, continuous improvement, and customer focus guide everything we do. As we continue to grow, we're looking for talented individuals who are excited to contribute to cutting-edge technology and make a meaningful impact in the scientific community.
Please note: This job posting was updated and revised effective April 17, 2026.
Position: Sr. Mechanical Design Engineer
Work Arrangement: On-Site Position (No Remote Option)
Corporate Office: San Ramon, California
Relocation Assistance: No (Local Candidates Are Encouraged to Apply and Will Be Given Preference)
Closing: Continuous Recruitment. We are accepting and reviewing all qualified applicants who meet the minimum requirements which are listed in this announcement for consideration on an ongoing basis.
Application Screening Process: Your application will not be considered if you fail to meet the minimum qualifications listed below or do not submit a detailed cover letter and resume as required for the application screening process.
Salary: $120,000 - $155,000 per year.
The successful candidate's starting base will be determined based on permissible, non-discriminatory factors such as skills, experience, and geographic location. It is not typical for an individual to be hired at or near the top of the base range for this role.
Who You Are
You are a skilled mechanical engineer who combines strong technical ability with creative problem-solving. You communicate clearly, work well with cross-functional teams, and adapt quickly in fast-moving environments. You take ownership of your work, move comfortably from concept to prototype, and bring a practical, hands-on approach to developing advanced instrumentation.
Summary
The Sr. Mechanical Engineer is responsible for planning and executing mechanical engineering tasks for the product development of advanced instruments. This individual will be working closely with other members of our interdisciplinary team developing innovative advanced related products and technologies. The candidate must be a fast learner, strong problem solver, and exceptional communicator. This position will require you to translate ideas into high-level design concepts and working prototypes. The candidate must have a proven ability to understand complex problems and requirements as described by customers, product liaisons, scientific and engineering team members.
Job Responsibilities and Expectations
This is not necessarily an all-inclusive list of job-related responsibilities, duties, skills, efforts, requirements, or working conditions. While this is intended to be an accurate reflection of the current job, management reserves the right to revise the job or to require that other or different tasks be performed as assigned.
  • Design all advanced instrument parts and assemblies using SOLIDWORKS to meet specifications and for Design for Manufacturability (DFM) on integrated microfluidics, pneumatic, and liquid handling systems.
  • Create test fixtures for Design of Experiments (DOE) as well as Verification, and Validation processes.
  • Perform experimental testing and analyze resulting data.
  • Lead project teams in the preparation of engineering inputs, cost estimates, schedules, and project management.
  • Prepare for, and participate in, comprehensive design reviews.
  • Evaluate performance at the component and system levels via both SOLIDWORKS modeling and hands-on experimental methods.
  • Develop and execute component reliability and qualification tests.
  • Develop quality procedures to support the manufacturing team in pilot builds and troubleshooting during production.
  • Write engineering change orders on existing products to improve designs and correct problems.
  • Meet deadlines, sustain superior personal task management, and deliver consistent high performance.
  • Perform other department-specific duties as assigned.

Minimum Qualifications
  • Bachelor's degree in mechanical engineering or other closely related engineering disciplines.
  • High proficiency in using SOLIDWORKS for mechanical design and documentation. GD&T experience is highly desirable.
  • 5+ years of experience in mechanical engineering; with a proven track record of developing advanced instruments is a Plus!
  • Experience with micro injection molding, designs of electrical connectors, motion controls, chassis designs, and various valves is a strong Plus!
  • Experience with lab automation systems is a Plus!
  • Working knowledge of microfluidic and MEMs processes is a Strong Plus!
  • Ability to read, analyze and interpret technical drawings, processes, and specifications.
  • Possess excellent analytical and problem-solving skills.
  • Ability to communicate effectively, oral and written.
  • Being a flexible team player with strong leadership.
  • Be adaptable to a fast-paced and high-growth environment.
  • Previous exposure to integrated analytical systems using microfluid components is a huge plus!

Physical Requirements
These physical requirements are not exhaustive, and additional job-related physical requirements may be added to these on an as-needed basis.
  • Ability to sit or stand for extended periods while working at a computer, lab bench, or assembly station
  • Ability to walk between office, laboratory, and light-manufacturing areas throughout the workday
  • Ability to lift, carry, and move equipment, prototypes, or components up to 25-40 lbs
  • Manual dexterity to assemble, adjust, and test small mechanical and microfluidic components
  • Ability to use precision tools and instruments, including calipers, micrometers, torque drivers, and hand tools
  • Ability to bend, reach, kneel, or crouch occasionally to access equipment, test setups, or storage areas
  • Adequate vision and hand-eye coordination for detailed inspection, assembly, and reading engineering drawings
  • Able to work safely in laboratory environments, including wearing PPE such as safety glasses, gloves, and lab coats
  • Ability to tolerate moderate noise levels typical of lab and light-manufacturing environments
  • Ability to handle chemicals, adhesives, and cleaning agents in accordance with safety guidelines
  • Ability to travel occasionally for vendor visits, customer support, or field evaluations (if required)

What We Offer
At RheoSense, you can build an excellent job that grows into a meaningful and rewarding career. Our comprehensive benefits and workplace culture include:
  • Financial stability through competitive compensation, performance incentives, and retirement plans
  • Training and professional development to support long-term career growth
  • Health and welfare benefits, including medical, dental, vision, life insurance, and wellness programs
  • Paid Time Off (PTO) to support work-life balance
  • Paid parental leave for both maternity and paternity
  • 401(k) retirement savings plan with a company match of up to 4%
  • Employee stock ownership (ISO) opportunities
  • A collaborative, creative, inclusive, and engaging team environment

RheoSense is an equal-opportunity employer and is committed to maintaining a diverse and inclusive workplace.

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