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Medical Information Systems Jobs (NOW HIRING)

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Medical Information Systems information

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$44K

$105.8K

$149.5K

How much do medical information systems jobs pay per year?

As of Aug 14, 2026, the average yearly pay for medical information systems in the United States is $105,783.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,000.00 and $129,500.00 per year, depending on experience, location, and employer.

What are medical information systems?

Medical information systems are specialized software and technology platforms used in healthcare settings to manage, store, and exchange patient data and medical records. These systems streamline workflows by organizing clinical, administrative, and financial information, improving the quality and efficiency of patient care. Examples include Electronic Health Records (EHR), laboratory information systems, and radiology information systems. By centralizing data, medical information systems enhance communication among healthcare providers and support better decision-making.

What are the key skills and qualifications needed to thrive as a medical information systems professional?

To thrive as a Medical Information Systems professional, you need expertise in health informatics, data management, and healthcare regulations, typically supported by a degree in health information management or related fields. Familiarity with electronic health record (EHR) systems, database management tools, and certifications like RHIA or RHIT are commonly required. Strong analytical thinking, attention to detail, and effective communication are essential soft skills for success in this role. These skills enable accurate data handling, regulatory compliance, and seamless information flow that support high-quality patient care.

What is the difference between Medical Information Systems vs Medical Data Analysts?

AspectMedical Information SystemsMedical Data Analysts
Required CredentialsHealth IT certifications, degrees in health informatics or related fieldsStatistics, data analysis, or health informatics degrees, certifications in data analysis tools
Work EnvironmentHospitals, clinics, health IT companies, healthcare organizationsResearch institutions, healthcare providers, data-focused departments
Employer & Industry UsageImplementing and managing healthcare software systemsAnalyzing healthcare data to improve patient outcomes and operational efficiency

Medical Information Systems professionals focus on implementing, managing, and maintaining healthcare software and systems, ensuring data security and compliance. Medical Data Analysts interpret healthcare data to generate insights, support decision-making, and improve patient care. While both roles require health informatics knowledge, their core functions differ: one manages systems, the other analyzes data.

What are the most common challenges faced by professionals working in medical information systems, and how can they be addressed?

Professionals in Medical Information Systems often encounter challenges such as ensuring data security and patient privacy, integrating new technologies with existing systems, and maintaining regulatory compliance. Staying up to date with evolving healthcare regulations and cybersecurity best practices is essential. Collaboration with IT, clinical staff, and compliance teams is key to successfully addressing these challenges and ensuring that systems run smoothly and securely.
More about Medical Information Systems jobs

What cities are hiring for Medical Information Systems jobs?

Cities with the most Medical Information Systems job openings:

What states have the most Medical Information Systems jobs?

States with the most job openings for Medical Information Systems jobs include:

Infographic showing various Medical Information Systems job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 15% Part Time, and 6% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $105,783 per year, or $50.9 per hour.

Information Systems Security Officer

System One

Clarksburg, MD โ€ข On-site

$150K/yr

Other

Medical, Dental, Vision, Life, Retirement

Posted 23 days ago


Job description

Title: Information Systems Security Officer (ISSO) Location: Clarksburg, MD (Onsite) Type: Direct Hire Compensation: $150,000/year (salary) Schedule: 40 hours/week Clearance Required: Active TS/SCI with Polygraph (required to start)

Role Overview

We’re hiring an Information Systems Security Officer (ISSO) to support mission-critical, classified environments. In this role, you’ll help ensure information systems stay compliant throughout the Risk Management Framework (RMF) lifecycle—supporting ATO packages, continuous monitoring, assessments, and audit readiness. You’ll partner closely with technical teams and security stakeholders to drive secure, compliant system operations.

What You’ll Do (Key Responsibilities)

  • Support the full RMF lifecycle for classified information systems
  • Build and maintain security authorization packages and RMF documentation
  • Coordinate and support Authority to Operate (ATO) efforts
  • Perform/control security assessments, compliance reviews, and control validation
  • Track vulnerabilities, findings, and remediation activities (POA&Ms, etc.)
  • Support Continuous Monitoring (ConMon) and ongoing security activities
  • Review scan results/configurations to ensure alignment with security requirements
  • Work with system teams to implement/maintain required security controls
  • Participate in audits, inspections, and cybersecurity compliance reviews
  • Provide risk-based recommendations to improve security posture

Required Qualifications (Must-Haves)

  • Active TS/SCI with Polygraph
  • Experience in ISSO / Information Assurance / cybersecurity compliance in classified environments
  • Strong knowledge of RMF and the security authorization process (ATO)
  • Familiarity with:
    • NIST SP 800-53 (Rev 3 and/or Rev 5)
    • NIST SP 800-37
  • Experience with compliance/configuration scanning and assessment workflows
  • Strong communication skills (written + verbal) and comfort working cross-functionally

Tools/Platforms (Experience With)

Experience with RMF/cyber compliance tools such as:

  • XACTA
  • LATTE / ART
  • BISCOTTI
  • WATCHCAT
  • STE (Experience with similar tools is also valuable.)

Documentation You Should Be Comfortable With

Hands-on experience developing/reviewing security documentation such as:

  • SSP, POA&M, SAR, RAR
  • CMP, CP, BIA
  • SPFs / exceptions and related artifacts
  • AARs and audit support documentation

Preferred / Nice-to-Have

  • Prior support of classified government systems
  • Experience partnering with ISSMs, System Owners, Security Control Assessors, and Authorizing Officials
  • Familiarity with vulnerability remediation and system administration security concepts
  • Certifications like Security+, CISSP, CAP, CASP+, or CISM

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

#M-1 #LI- Ref: #851-Rockville-S1