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Mass Spectrometry Orbitrap Jobs (NOW HIRING)

Allergan

$125 - $150/hr

Operate, maintain, and troubleshoot mass spectrometry (Orbitrap, TOF) and liquid chromatography platforms, along with general laboratory equipment. * Document instrument performance, organize regular ...

Baylor College of Medicine

WI · On-site

$60 - $80/hr

The lab is well-equipped with Thermos UHPLC-Q Exactive MS, Orbitrap Exploris 120, Thermo Quintus (triple quadruple), and Imaging mass spectrometry (IMS, Bruker timsTOF fleX MALDI-2). The position ...

University of Virginia

Senior Scientist

Charlottesville, VA · On-site

$90K - $124K/yr

Possess prior experience in qualitative and quantitative proteomics and metabolomics technology and nano-liquid chromatography and mass spectrometry (LC-MS; on Orbitrap Fusion, Orbitrap Astral, and ...

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Mass Spectrometry Orbitrap information

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How much do mass spectrometry orbitrap jobs pay per hour?

As of Sep 8, 2026, the average hourly pay for mass spectrometry orbitrap in the United States is $22.62, according to ZipRecruiter salary data. Most workers in this role earn between $18.51 and $24.04 per hour, depending on experience, location, and employer.

What is a mass spectrometry Orbitrap and how is it used?

A Mass Spectrometry Orbitrap is a high-resolution mass spectrometer that uses an electrostatic field to trap ions for precise measurement of their mass-to-charge ratios. It is commonly used in proteomics, metabolomics, and other analytical chemistry fields to identify and quantify complex mixtures of biomolecules. Orbitrap instruments are valued for their high accuracy, sensitivity, and ability to analyze a wide range of sample types, making them essential in research, pharmaceutical, and clinical labs.

What are the key skills and qualifications needed to thrive as a mass spectrometry Orbitrap specialist, and why are they important?

To thrive as a Mass Spectrometry Orbitrap Specialist, you need a solid background in analytical chemistry, experience with mass spectrometry techniques, and often an advanced degree in chemistry or a related field. Familiarity with Orbitrap mass analyzers, associated data analysis software (like Xcalibur), and laboratory information management systems (LIMS) is crucial. Strong problem-solving skills, attention to detail, and effective communication help you interpret complex data and collaborate with interdisciplinary teams. These skills ensure accurate results, efficient operation of sophisticated equipment, and meaningful scientific contributions.

What are some common challenges faced by professionals working with Orbitrap mass spectrometry instruments, and how can they be addressed?

Professionals working with Orbitrap mass spectrometry instruments often encounter challenges such as instrument calibration drift, complex sample preparation, and troubleshooting sensitivity or resolution issues. Regular maintenance, strict adherence to calibration protocols, and thorough training in sample handling can help mitigate these problems. Additionally, collaborating with colleagues in analytical chemistry and bioinformatics can aid in data interpretation and troubleshooting, fostering a supportive environment for problem-solving and continuous learning.

What is the difference between Mass Spectrometry Orbitrap vs Mass Spectrometry Technician?

AspectMass Spectrometry OrbitrapMass Spectrometry Technician
CredentialsBachelor's degree in chemistry, biochemistry, or related field; specialized training in Orbitrap instrumentsAssociate's or bachelor's degree; training in mass spectrometry techniques
Work EnvironmentResearch labs, pharmaceutical companies, or academic institutionsAnalytical labs, manufacturing facilities, or research settings
Job FocusOperating and maintaining Orbitrap instruments, data analysis, method developmentSample preparation, instrument operation, data collection, troubleshooting

While both roles involve mass spectrometry, the Mass Spectrometry Orbitrap specialist focuses on advanced instrument operation and data analysis, often requiring specialized training. The Mass Spectrometry Technician handles routine sample processing and instrument maintenance. The Orbitrap role is more research and analysis-oriented, whereas the technician role emphasizes hands-on sample handling and troubleshooting.

What other helpful pages are available for Mass Spectrometry Orbitrap?

Other pages related to Mass Spectrometry Orbitrap:

Infographic showing various Mass Spectrometry Orbitrap job openings in the United States as of September 2026, with employment types broken down into 80% Full Time, 19% Part Time, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $47,050 per year, or $22.6 per hour.

Senior Research Lab Tech, Mass Spectrometry

Cambridge, MA • On-site

Jobtailor
See more jobs at Jobtailorexternal

$100 - $125/hr

Other

Posted 3 days ago

New

Job description

• Run and maintain the laboratory's mass spectrometry platform
• Execute workflows spanning human tissue processing, immunofluorescence imaging, laser microdissection, low-input proteomic sample preparation, and ultra-sensitive mass spectrometry
• Generate high-quality proteomic data on the Orbitrap Astral
• Work closely with postdoctoral and computational colleagues
• Help establish core methods and operational standards
• Develop or contribute to modifications of assay techniques, experimental protocols, and new procedures
• Synthesize and interpret results
• Prepare written and/or verbal status reports
• Perform statistical analysis and make recommendations
• Independently perform non-routine, highly specialized experimental procedures
• Compose and potentially present sections of research reports and manuscripts

Requirements

  • Bachelor's Degree in a related field required (Biochemistry, Analytical Chemistry, Molecular Biology, or a related field)
  • 3–5 years of experience in an academic or laboratory research setting required
  • Minimum of 3 years of hands-on LC-MS experience required
  • Hands-on operation, routine maintenance, and systematic troubleshooting of complex LC-MS setups for high-throughput quantitative proteomics
  • Prior experience with nanoflow workflows and the Orbitrap Astral, Vanquish Neo, and Evosep One highly desirable
  • Expertise in protein extraction and enzymatic digestion
  • Experience with low-input workflows and PTM enrichments such as phosphoproteomics ideally
  • Experience optimizing and troubleshooting protocols and MS acquisition methods
  • Experience documenting rigorous laboratory SOPs
  • Practical experience with human tissue sectioning, including cryosectioning and FFPE, immunofluorescence staining, or laser microdissection is a strong advantage
  • Excellent communication skills
  • Good interpersonal skills and ability to oversee the work of others
  • Ability to work independently
  • Ability to identify problems and develop solutions
  • Ability to prioritize tasks and set deadlines
  • Strong database management and overall computer skills
  • Ability to function with speed, precision, and understanding of the theory behind tests and procedures

Core Competencies

Demonstrates expertise in mass spectrometry, particularly with LC-MS and the Orbitrap Astral, while effectively synthesizing and interpreting proteomic data. Capable of developing and optimizing experimental protocols and maintaining rigorous laboratory standards.

Highest-signal resume keywords

  • LC-MS Experience
  • Orbitrap Astral Operation
  • Protein Extraction Expertise
  • Statistical Analysis Skills
  • Laboratory SOP Documentation

ATS Optimization Keywords

Hard Skills

  • Mass Spectrometry
  • Proteomic Sample Preparation
  • Human Tissue Processing
  • Immunofluorescence Imaging
  • Laser Microdissection
  • Statistical Analysis
  • Assay Technique Development
  • Experimental Protocol Modification
  • Low-Input Workflows
  • PTM Enrichment

Soft Skills

  • Excellent Communication Skills
  • Interpersonal Skills
  • Problem-Solving Ability
  • Independence
  • Task Prioritization

Industry Keywords

  • Biochemistry
  • Analytical Chemistry
  • Molecular Biology
  • Laboratory Research
  • High-Throughput Quantitative Proteomics

Tools & Technologies

  • Orbitrap Astral
  • Vanquish Neo
  • Evosep One
  • Database Management Software
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