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Mass Spectrometry Engineer Jobs (NOW HIRING)

A Master's degree or higher in chemistry, chemical engineering, materials science, or a related field. * Working familiarity with mass spectrometry. * Knowledge of organic chemical structures and ...

This role will leverage and develop the next phase of automation development in mass spectrometry supporting the Cell Engineering and Analytical Sciences group. The role blends hands-on robotic ...

Scientist I, Research

Bartlesville, OK · On-site

$108K - $133K/yr

Bachelor's degree in Chemistry, Physics, Material Science, or a closely related science or engineering discipline * 2 or more years of hands-on experience in Chromatography and/or Mass Spectrometry ...

Scientist I, Research

Bartlesville, OK · On-site

$108K - $133K/yr

Bachelor's degree in Chemistry, Physics, Material Science, or a closely related science or engineering discipline * 2 or more years of hands-on experience in Chromatography and/or Mass Spectrometry ...

Showing results 41-60

Mass Spectrometry Engineer information

What does a mass spectrometry engineer do?

A Mass Spectrometry Engineer specializes in the design, operation, maintenance, and troubleshooting of mass spectrometry equipment used for chemical analysis. They work in laboratories to ensure accurate measurements of molecular and atomic particles, often supporting research, pharmaceutical, environmental, or industrial applications. Their responsibilities may include calibrating instruments, developing analytical methods, and interpreting data to help identify substances within a sample. Additionally, they may provide technical support and training to other laboratory staff.

What are the key skills and qualifications needed to thrive as a mass spectrometry engineer?

To thrive as a Mass Spectrometry Engineer, you need a solid background in analytical chemistry, physics, and engineering, often supported by a relevant bachelor's or master's degree. Familiarity with mass spectrometry instrumentation, data analysis software, and laboratory information management systems (LIMS) is typically required. Strong problem-solving abilities, attention to detail, and effective communication skills help set top candidates apart. These skills and qualities are crucial for ensuring precise data generation, maintaining equipment reliability, and facilitating collaboration with research teams.

What are some common challenges faced by mass spectrometry engineers in maintaining and troubleshooting instrumentation?

Mass Spectrometry Engineers often encounter challenges such as diagnosing complex instrument malfunctions, ensuring consistent calibration for accurate results, and managing contamination issues that can affect sensitivity. These professionals must stay up-to-date with evolving technology and software, as well as maintain detailed documentation for regulatory compliance. Collaboration with laboratory scientists and IT support is crucial to resolve technical problems quickly and minimize instrument downtime.

What is the difference between Mass Spectrometry Engineer vs Analytical Chemist?

AspectMass Spectrometry EngineerAnalytical Chemist
CredentialsBachelor's or Master's in Chemistry, Biochemistry, or related field; specialized training in mass spectrometryBachelor's or Master's in Chemistry, Analytical Chemistry, or related field; often with certifications in laboratory techniques
Work EnvironmentLaboratories, R&D departments, instrument development settingsResearch labs, quality control labs, environmental testing facilities
Industry UsagePharmaceuticals, biotech, environmental analysis, forensicsPharmaceuticals, manufacturing, environmental testing, academia

The main difference is that Mass Spectrometry Engineers focus on developing, maintaining, and optimizing mass spectrometry instruments and techniques, while Analytical Chemists apply these techniques to analyze samples and interpret data. Both roles require strong chemistry backgrounds, but their daily tasks and focus areas differ.

What cities are hiring for Mass Spectrometry Engineer jobs?

Cities with the most Mass Spectrometry Engineer job openings:

What states have the most Mass Spectrometry Engineer jobs?

States with the most job openings for Mass Spectrometry Engineer jobs include:

What are popular job titles related to Mass Spectrometry Engineer jobs?

For Mass Spectrometry Engineer jobs, the most frequently searched job titles are:

Infographic showing various Mass Spectrometry Engineer job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 89% Full Time, 7% Part Time, and 3% Contract. Highlights an 84% Physical, 5% Hybrid, and 11% Remote job distribution.

QA with Domain experience - Chromatography and mass spectrometry - Santa Clara CA - Hybrid

Prosper, TX • On-site

Full-time

Posted 19 days ago


Job description

Title: QA with domain experience (Chromatography and mass spectrometry)
Domain: Background in Chemistries
Location: Santa Clara, CA - Hybrid (3 Days onsite - Tuesday, Wednesday, Thursday)

Job Description
  • Background in Chemistries 
  • Familiarity with Chromatography and mass spectrometry HW and Applications (GC/LC/MS QTOF)
  • Perform sample analysis, data processing, calibration, and maintenance of all chromatography systems
  • Prepare reagents needed for analysis
  • Perform instrument tuning and calibration
  • Experience developing test designs and test cases for verification and validation of product functionality through manual and automated E2E tests
  • Software solutions test planning
  • Define and execute feature test cases
  • Investigate errors, report potential software defects, and verify fixes
  • Assess software performance
  • Work in an agile development environment testing iteratively against newly developed code until quality metrics are achieved from an end customer's perspective
  • Work with Engineering and Product Management teams to clearly communicate test results, recommended next steps, and timing for the next phase of feature releases
  • Review and validate software requirements and functional design specifications
  • Troubleshoot system issues and defects with Support, R&D, and implementation teams, propose solutions, test resolutions, and facilitate release to production
  • Develop QA estimates for project and enhancement requests. Assist in scoping, planning, and scheduling QA activities.
 
Note: This role follows a hybrid work schedule, with onsite presence at the Santa Clara office Tuesday, Wednesday and Thursday and remote work on Monday and Friday.
 
Qualifications:
  • Bachelor's or Master's Degree in Chemistry, Computer Science, or other related field, or equivalent experience
  • 1+ years of experience in QTOF, LC, or GC Chromatography, including running samples and reporting results a plus
  • Good verbal and written communication skills
  • Experience with laboratory informatics software such as a networked Chromatography Data System (CDS), Laboratory Information Management System (LIMS), Electronic Laboratory Notebook (ELN), or Scientific Data Management System (SDMS)
  • Experience in Jenkins, JMeter Benchmark, and Postman is a Plus
  • Desired experience with test automation or software programming knowledge (C#, scripting such as Playwright, Groovy, PowerShell, REST API )