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Manufacturing Plant Manager Jobs in Raleigh, NC (NOW HIRING)

Arclin

Operations Manager III

Moncure, NC · On-site

... Manufacturing department. * Work with other functional leaders (internal to plant and corporate) to ... Operations Manager Job Requirements: * Bachelors' Degree in Chemical Engineering, Operations or ...

Arclin USA LLC

Operations Manager III

Moncure, NC

... Manufacturing department. * Work with other functional leaders (internal to plant and corporate) to ... Operations Manager Job Requirements: * Bachelors' Degree in Chemical Engineering, Operations or ...

Utility Plant Solutions Inc

Be Seen First

Utility Plant Solutions - Boiler Technician

Wake Forest, NC · On-site

$30 - $40/hr

Our customers consist of Universities, Pharmaceutical Companies, Power Plants, Manufacturing and ... The Technician will be responsible for coordinating, managing, and installation of mechanical and ...

Utility Plant Solutions Inc

Be Seen First

Utility Plant Solutions - Boiler Technician

Wake Forest, NC · On-site

$30 - $40/hr

Our customers consist of Universities, Pharmaceutical Companies, Power Plants, Manufacturing and ... The Technician will be responsible for coordinating, managing, and installation of mechanical and ...

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All JobsManufacturing Plant JobsManufacturing Plant Manager JobsManufacturing Plant Manager Jobs in Raleigh, NC

Manufacturing Plant Manager information

See Raleigh, NC salary details

$39.4K

$113.2K

$174K

How much do manufacturing plant manager jobs pay per year?

As of Aug 7, 2026, the average yearly pay for manufacturing plant manager in Raleigh, NC is $113,164.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,500.00 and $136,600.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a manufacturing plant manager, and why are they important?

To thrive as a Manufacturing Plant Manager, you need strong leadership, operations management expertise, and a background in engineering or business, often supported by a relevant bachelor's degree. Familiarity with ERP systems, lean manufacturing methodologies, and certifications like Six Sigma are typically required. Outstanding problem-solving, communication, and team-building skills help drive productivity and foster a positive work environment. These capabilities are essential for ensuring efficient plant operations, meeting production targets, and maintaining high safety and quality standards.

What does a manufacturing plant manager do?

Manufacturing plant managers oversee the daily operations of a manufacturing production facility. As a manufacturing plant manager, you manage a team of supervisors as well as the workers on the production line. Your duties include planning production schedules, identifying productivity goals, and monitoring processes to ensure efficiency in the manufacturing process. To achieve your department goals, you collaborate with your line supervisors, the sales and operations departments, and other managers or executives.

What is the difference between Manufacturing Plant Manager vs Production Supervisor?

AspectManufacturing Plant ManagerProduction Supervisor
ResponsibilitiesOversees entire plant operations, strategic planning, and management of departmentsManages daily production activities, supervises line workers, ensures production targets are met
Required CredentialsBachelor's degree in engineering, manufacturing, or related field; often experience in managementHigh school diploma or associate degree; experience in manufacturing or production roles
Work EnvironmentOffice setting with plant floor oversightPrimarily on the production floor
Industry UsageCommonly used in manufacturing plants across various industriesUsed in manufacturing settings to supervise production lines

The Manufacturing Plant Manager focuses on overall plant operations, strategic planning, and management, while the Production Supervisor handles daily production activities and team supervision. Both roles are essential in manufacturing, but the Plant Manager has broader responsibilities and oversight.

What are some typical challenges a manufacturing plant manager faces in leading cross-functional teams?

Manufacturing Plant Managers often coordinate teams from production, quality assurance, maintenance, and logistics to ensure smooth operations. A common challenge is aligning diverse team goals while maintaining clear communication and timely problem-solving. Balancing productivity targets with safety and quality standards can also require strong leadership and adaptability. Successful Plant Managers build collaborative relationships and implement structured processes to foster teamwork and drive continuous improvement.

What does a manufacturing plant manager do?

A Manufacturing Plant Manager oversees the daily operations of a manufacturing facility, ensuring that production runs efficiently, safely, and meets quality standards. They are responsible for managing staff, coordinating production schedules, implementing safety protocols, and optimizing processes to reduce costs and improve productivity. Additionally, they often collaborate with other departments such as engineering, quality assurance, and supply chain management to achieve organizational goals.
More about Manufacturing Plant Manager jobs
What job categories do people searching Manufacturing Plant Manager jobs in Raleigh, NC look for? The top searched job categories for Manufacturing Plant Manager jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Manufacturing Plant Manager jobs? Cities near Raleigh, NC with the most Manufacturing Plant Manager job openings:
Manufacturing Plant Manager jobs near you
Infographic showing various Manufacturing Plant Manager job openings in Raleigh, NC as of July 2026, with employment types broken down into 87% Full Time, 12% Part Time, and 1% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution, with an average salary of $113,164 per year, or $54.4 per hour.

Front Line Manufacturing Manager - Downstream Bulk Drug Substance - Days

Amgen, Inc.

Holly Springs, NC • On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 8 days ago

Job description

Career Category
Manufacturing
Job Description
HOW MIGHT YOU DEFY IMAGINATION?
You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience, and passion to work toward your goals? At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX Batch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.
Front Line Manufacturing Manager - Downstream Bulk Drug Substance - Days
What you will do
Let's do this. Let's change the world. Amgen is seeking a Manager Manufacturing Downstream to provide frontline leadership supporting the facility expansion program and facility startup. This essential role will lead a team responsible for manufacturing downstream purification operations including column packing, column chromatography, TFF, viral filtration, viral inactivation, conjugation, and final fill while partnering across functions to ensure successful operational readiness, technology transfer, and ramp-up of manufacturing operations within the new facility.
The Manager will play a critical role supporting the design, build, startup, and operational phases of the facility expansion. The position will initially focus on facility startup and operational readiness activities, transitioning to manufacturing leadership as the facility becomes operational. During this phase of the startup, you will be expected to work a Monday - Friday schedule from 8am - 5pm.
This role may require work outside standard business hours, including non-standard shifts, as needed to support startup, commissioning and qualification (C&Q), and engineering execution. As the business moves from C&Q to manufacturing operations, this essential position will work on a 12-hour 2-2-3 schedule from 5:45 am to 6:15pm supporting our critical 24/7 manufacturing operations. As Amgen relies upon the regular attendance of all staff members to meet legitimate business needs, the Manager must be able to work assigned 12-hour shift, including during inclement weather, some holidays and requested overtime in support of our operations.
Responsibilities
  • Frontline Leadership: Lead, develop, and coach a manufacturing team; set clear performance expectations; foster a strong culture of safety, quality, and accountability.

  • Facility Startup & Operational Readiness: Support design, build, commissioning, qualification (C&Q), staffing, training, and readiness milestones for a new manufacturing facility.

  • Manufacturing Operations: Ensure safe, cGMP-compliant execution; drive performance across safety, quality, schedule, and cost; resolve deviations and operational issues.

  • Technology Transfer & Process Implementation: Support transfer and implementation of manufacturing processes; ensure manufacturability, troubleshooting, and continuous improvement.

  • Cross-Functional Collaboration: Partner with Quality, Engineering, NPI, Supply Chain, Validation, and Site Leadership to enable successful startup and ramp-up.

  • Compliance & Inspection Readiness: Maintain inspection readiness and adherence to regulatory and Amgen quality standards.

  • Continuous Improvement: Identify and drive efficiency, reliability, and scalability improvements as operations mature.

  • Shift Support: Work non-standard hours as required, transitioning to a 12-hour 2-2-3 day shift supporting 24/7 operations.

Win
What we expect from you
We are all different, yet we all use our unique contributions to serve patients. The biotechnology professional we seek is a manager with these qualifications.
Basic Qualifications
  • Doctorate degree OR
  • Master's degree and 3 years of Manufacturing or Operations experience OR
  • Bachelor's degree and 5 years of Manufacturing or Operations experience OR
  • Associate's degree and 10 years of Manufacturing or Operations experience OR
  • High school diploma / GED and 12 years of Manufacturing or Operations experience
  • AND Previous managerial experience directly managing people and/or experience leading teams, projects, programs or directing the allocation of resources

Preferred Qualifications
  • Bachelor's degree in Life Sciences or Engineering

  • Experience with facility startup, commissioning, or operational readiness

  • Biologics / drug substance manufacturing experience (downstream)

  • cGMP manufacturing experience (5+ years preferred)

  • Experience with technology transfer and process implementation

  • Prior Area Lead / Specialist / Manager experience

  • Strong leadership, performance management, and conflict-resolution skills

  • Solid understanding of regulatory requirements

  • Proficiency with MES/EBR, DeltaV, Maximo, Veeva, LIMS, and electronic quality systems

Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.
The annual base salary range for this opportunity in the U.S. is provided below.
In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible

Apply now for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
#AmgenNorthCarolina
Salary Range
106,148.00USD -143,612.00 USD

Apply