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Manufacturing Execution System Engineer Jobs (NOW HIRING)

Leidos

Manufacturing Systems Engineer

Huntsville, AL · On-site

$73K - $132K/yr

This is an exciting opportunity for an experienced Manufacturing Engineer to oversee ... Execution System) as well as develop analytics to create KPI's and dashboards for monitoring our ...

New

Leidos

Manufacturing Systems Engineer

Huntsville, AL · On-site

This is an exciting opportunity for an experienced Manufacturing Engineer to oversee ... Execution System) as well as develop analytics to create KPI's and dashboards for monitoring our ...

New

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Manufacturing Execution System Engineer information

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$40.5K

$110.2K

$158.5K

How much do manufacturing execution system engineer jobs pay per year?

As of Aug 20, 2026, the average yearly pay for manufacturing execution system engineer in the United States is $110,216.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,000.00 and $142,500.00 per year, depending on experience, location, and employer.

What is the difference between Manufacturing Execution System Engineer vs Manufacturing Technician?

AspectManufacturing Execution System EngineerManufacturing Technician
CredentialsBachelor's degree in engineering, computer science, or related field; certifications in MES or automationHigh school diploma or technical training; certifications vary
Work EnvironmentDesign, implement, and maintain MES software in manufacturing plantsOperate and troubleshoot manufacturing equipment on the shop floor
Industry UsageUsed across manufacturing sectors for process control and data managementHands-on production and equipment operation in factories

The Manufacturing Execution System Engineer focuses on developing and maintaining MES software systems to optimize manufacturing processes, while the Manufacturing Technician handles the day-to-day operation and troubleshooting of manufacturing equipment. Both roles are essential but differ in technical scope and responsibilities.

What cities are hiring for Manufacturing Execution System Engineer jobs?

Cities with the most Manufacturing Execution System Engineer job openings:

What states have the most Manufacturing Execution System Engineer jobs?

States with the most job openings for Manufacturing Execution System Engineer jobs include:

Infographic showing various Manufacturing Execution System Engineer job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 85% Full Time, 11% Part Time, and 3% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $110,216 per year, or $53 per hour.

Engineer II, Manufacturing Execution Systems

Moderna

Norwood, MA • On-site

Full-time

Re-posted 23 days ago

Moderna rating

9.2

Company rating: 9.2 out of 10

Based on 10 frontline employees who took The Breakroom Quiz

5th of 86 rated pharmaceutical

Job description

Job Summary:
Moderna is a leading mRNA technology company focused on transforming medicine. The Engineer II will serve as a frontline partner for Operations, providing user support for manufacturing digital systems and implementing improvements across the manufacturing network.
Responsibilities:
• Serve as the first point of contact for shop-floor users; troubleshoot complex issues, resolve, and document issues for Apprentice Tempo, Syncade, DeltaV, Aveva SCADA Platform, Aveva PI, and BMS.
• Perform structured troubleshooting across application, configuration, and basic infrastructure layers; escalate effectively when needed.
• Coordinate with Operations, Quality, and IT to restore service quickly and minimize production impact.
• Maintain and improve support knowledge (runbooks, KB articles, SOPs) and provide targeted user coaching and quick tips to reduce repeat issues.
• Execute standard change-control activities related to support (e.g., minor configuration updates, record corrections, documentation) in alignment with GxP and data-integrity expectations.
• Monitor system health and alerts; identify patterns and propose corrective and preventive actions (CAPAs) or continuous improvement suggestions.
• Participate in planned maintenance windows for support validation and post-maintenance checks.
• Contribute to compliance activities (deviations, investigations, periodic reviews) from a systems-support perspective.
• Mentor junior team members through shadowing, ticket reviews, and feedback on documentation; support onboarding and skills development to build a resilient frontline support function.
Qualifications:
Required:
• Bachelor’s degree in Information Technology, Engineering, or a related field.
• 2-3 years of hands-on experience with Manufacturing Execution Systems.
• Clear communication skills, with the ability to convey complex information in an understandable manner to various stakeholders.
• Ability to work first, second, or third shifts to support 24/7 operation.
• This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.
• Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship.
Preferred:
• Depth in two or more systems: Tempo, Syncade, Aveva SCADA, DeltaV, or BMS, with familiarity in their integrations.
• Experience in MES business processes for electronic batch record execution and a working knowledge of automation systems.
• Working understanding of cGMP manufacturing operations, GAMP, and CSV/change-control practices.
• Demonstrated strength in incident triage, root-cause analysis, and clear written documentation.
• Ability to partner effectively with cross-functional stakeholders under time-sensitive conditions.
• Understanding of integrated digital systems and be able to triage issues spanning multiple systems.
• Strong customer-service mindset; confident facilitating user training and delivering concise how-to.
• Experience coaching or mentoring junior engineers and contributing to team knowledge-sharing practices.
• Continuous-improvement orientation—experience reducing ticket volume through standardization or automation initiatives.
Company:
Moderna Therapeutics is a biotechnology company that develops medicines and vaccines based on messenger RNA (mRNA) technology. Founded in 2010, the company is headquartered in Cambridge, USA, with a team of 1001-5000 employees. The company is currently Late Stage.

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About Moderna

Sourced by ZipRecruiter

In just over a decade, Moderna has evolved from a research-focused company in the messenger RNA (mRNA) field to a leading enterprise with a diverse clinical portfolio of vaccines and therapeutics. With a strong intellectual property portfolio and state-of-the-art manufacturing capabilities, Moderna collaborates with global partners to advance groundbreaking science and achieve rapid scaling of production. Notably, Moderna's mRNA platform has enabled the development of therapies for various diseases, including infectious diseases, immuno-oncology, and cardiovascular conditions. Recognized as a top biopharmaceutical employer, Moderna fosters an inclusive and smoke-free work environment. The company is dedicated to equal employment opportunities and non-discrimination, ensuring that all employees and applicants are treated with respect and without bias based on factors like race, gender, religion, disability, or sexual orientation. Moderna is also committed to providing reasonable accommodations for individuals with disabilities, in accordance with applicable laws. To know more, visit www.modernatx.com.

Industry

Manufacturing

Company size

501 - 1,000 Employees

Headquarters location

Cambridge, MA, US

Year founded

2010

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