The primary work centers on nucleic acid purification and quantitative PCR (qPCR and digital ... Experience with freezer management systems or LIMS. * Experience with GraphPad Prism or other data ...
The primary work centers on nucleic acid purification and quantitative PCR (qPCR and digital ... Experience with freezer management systems or LIMS. * Experience with GraphPad Prism or other data ...
The primary work centers on nucleic acid purification and quantitative PCR (qPCR and digital ... Experience with freezer management systems or LIMS. * Experience with GraphPad Prism or other data ...
The primary work centers on nucleic acid purification and quantitative PCR (qPCR and digital ... Experience with freezer management systems or LIMS. * Experience with GraphPad Prism or other data ...
Lead the end-to-end design and engineering of nucleic acid drug substances across mRNA, siRNA, gRNA ... management of antibody discovery vendors or CRO partnerships, with attention to affinity ...
Lead the end-to-end design and engineering of nucleic acid drug substances across mRNA, siRNA, gRNA ... management of antibody discovery vendors or CRO partnerships, with attention to affinity ...
Scientist, R&D
San Carlos, CA · On-site
Strong understanding of the chemistry underlying nucleic acid extraction, PCR, NGS library ... Ability to manage multiple priorities in a fast-paced, dynamic environment * Proficient in data ...
Scientist, R&D
San Carlos, CA · On-site
Strong understanding of the chemistry underlying nucleic acid extraction, PCR, NGS library ... Ability to manage multiple priorities in a fast-paced, dynamic environment * Proficient in data ...
Scientist, Applications Sample Preparation
Berkeley, CA · On-site
$43.25 - $54.25/hr
Apply and adapt enrichment, depletion, and dynamic-range management protocols to improve input ... Hands-on experience executing sample preparation protocols across proteomic and nucleic acid-based ...
Scientist, Applications Sample Preparation
Berkeley, CA · On-site
$43.25 - $54.25/hr
Apply and adapt enrichment, depletion, and dynamic-range management protocols to improve input ... Hands-on experience executing sample preparation protocols across proteomic and nucleic acid-based ...
Scientist, Applications Sample Preparation
$43.25 - $54.25/hr
Apply and adapt enrichment, depletion, and dynamic-range management protocols to improve input ... Hands-on experience executing sample preparation protocols across proteomic and nucleic acid-based ...
Scientist, Applications Sample Preparation
$43.25 - $54.25/hr
Apply and adapt enrichment, depletion, and dynamic-range management protocols to improve input ... Hands-on experience executing sample preparation protocols across proteomic and nucleic acid-based ...
Clinical Laboratory Scientist
Laguna Hills, CA · On-site
$45 - $50/hr
... FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality ... Experience in project management and organization * Excellent record-keeping and documentation ...
Quick apply
Clinical Laboratory Scientist
Laguna Hills, CA · On-site
$45 - $50/hr
... FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality ... Experience in project management and organization * Excellent record-keeping and documentation ...
Manager, NGS Lab
Hayward, CA · On-site
Key Responsibilities & Time Allocation % of TimeResponsibility30% Daily Lab Operations Management -- Lead daily wet-lab operations, including sample accessioning, sample preparation, nucleic acid ...
Manager, NGS Lab
Hayward, CA · On-site
Key Responsibilities & Time Allocation % of TimeResponsibility30% Daily Lab Operations Management -- Lead daily wet-lab operations, including sample accessioning, sample preparation, nucleic acid ...
Supervisor, Oncology RUO
San Carlos, CA · On-site
Prior team management experience is highly preferred * Must pass a post-offer criminal background check KNOWLEDGE, SKILLS, AND ABILITIES: * Direct hands-on experience with nucleic acid techniques ...
Supervisor, Oncology RUO
San Carlos, CA · On-site
Prior team management experience is highly preferred * Must pass a post-offer criminal background check KNOWLEDGE, SKILLS, AND ABILITIES: * Direct hands-on experience with nucleic acid techniques ...
Principal/Senior Scientist, PK/PD Assays
South San Francisco, CA · On-site
$155K - $200K/yr
Track record of bioanalytical method transfer and CRO management for outsourced projects ... Experience with mRNA-LNP biodistribution or nucleic acid-based PK assays * Experience developing ...
Principal/Senior Scientist, PK/PD Assays
South San Francisco, CA · On-site
$155K - $200K/yr
Track record of bioanalytical method transfer and CRO management for outsourced projects ... Experience with mRNA-LNP biodistribution or nucleic acid-based PK assays * Experience developing ...
Sr Director, In Vivo Pharmacology
Redwood City, CA · On-site
$215K - $235K/yr
Oversee and manage the In vivo/Translational Biology group at Earli to support the growth and ... of nucleic acid-based drugs Required Experience, Knowledge and Skills * Required Experience ...
Sr Director, In Vivo Pharmacology
Redwood City, CA · On-site
$215K - $235K/yr
Oversee and manage the In vivo/Translational Biology group at Earli to support the growth and ... of nucleic acid-based drugs Required Experience, Knowledge and Skills * Required Experience ...
Principal/Senior Scientist, PK/PD Assays
$155K - $200K/yr
Track record of bioanalytical method transfer and CRO management for outsourced projects ... Experience with mRNA-LNP biodistribution or nucleic acid-based PK assays * Experience developing ...
Principal/Senior Scientist, PK/PD Assays
$155K - $200K/yr
Track record of bioanalytical method transfer and CRO management for outsourced projects ... Experience with mRNA-LNP biodistribution or nucleic acid-based PK assays * Experience developing ...
Environmental Health & Safety and Biosafety Senior Manager/Assistant Director
San Francisco, CA · On-site
... Nucleic Acid Molecules, providing critical support to researchers applying for NIH and other ... Develop, implement, and manage a comprehensive biosafety program ensuring compliance with ...
Environmental Health & Safety and Biosafety Senior Manager/Assistant Director
San Francisco, CA · On-site
... Nucleic Acid Molecules, providing critical support to researchers applying for NIH and other ... Develop, implement, and manage a comprehensive biosafety program ensuring compliance with ...
Prior experience managing early career engineers, scientist, or research associates. Expertise in ... Experience with facility design or equipment specification, for nucleic acid manufacturing. Deep ...
Prior experience managing early career engineers, scientist, or research associates. Expertise in ... Experience with facility design or equipment specification, for nucleic acid manufacturing. Deep ...
... nucleic acid sequencing and quantification, and related probes, kits, and reagents. Ideal ... experience managing patent portfolios, and the ability to collaborate effectively with cross ...
... nucleic acid sequencing and quantification, and related probes, kits, and reagents. Ideal ... experience managing patent portfolios, and the ability to collaborate effectively with cross ...
Environmental Health & Safety and Biosafety Senior Manager/Assistant Director
Stockton, CA · On-site
$90K - $99K/yr
... Manager/Assistant Director is responsible for developing, implementing, and maintaining ... Nucleic Acid Molecules, providing critical support to researchers applying for NIH and other ...
Environmental Health & Safety and Biosafety Senior Manager/Assistant Director
Stockton, CA · On-site
$90K - $99K/yr
... Manager/Assistant Director is responsible for developing, implementing, and maintaining ... Nucleic Acid Molecules, providing critical support to researchers applying for NIH and other ...
... nucleic acid sequencing and quantification, and related probes, kits, and reagents. Ideal ... experience managing patent portfolios, and the ability to collaborate effectively with cross ...
... nucleic acid sequencing and quantification, and related probes, kits, and reagents. Ideal ... experience managing patent portfolios, and the ability to collaborate effectively with cross ...
... nucleic acid sequencing and quantification, and related probes, kits, and reagents. Ideal ... experience managing patent portfolios, and the ability to collaborate effectively with cross ...
Quick apply
... nucleic acid sequencing and quantification, and related probes, kits, and reagents. Ideal ... experience managing patent portfolios, and the ability to collaborate effectively with cross ...
Principal Scientist - Oligonucleotide Design and Chemistry
South San Francisco, CA · On-site
$143K - $266K/yr
... nucleic-acid portfolio, communicating scientific progress, key milestones, and insights to multidisciplinary project teams and stakeholders. * Lab Excellence: Manage cutting-edge laboratory ...
Principal Scientist - Oligonucleotide Design and Chemistry
South San Francisco, CA · On-site
$143K - $266K/yr
... nucleic-acid portfolio, communicating scientific progress, key milestones, and insights to multidisciplinary project teams and stakeholders. * Lab Excellence: Manage cutting-edge laboratory ...
Biotechnology Technician (SRA 2 NEX)
Tulare, CA · On-site
$32.79 - $52.75/hr
... of nucleic acid-based detection using real time PCR and Standard PCR technology, including ... Key Responsibilities * 65% - Diagnostic Testing * 20% - Lab Management * 10% - Quality Management ...
Biotechnology Technician (SRA 2 NEX)
Tulare, CA · On-site
$32.79 - $52.75/hr
... of nucleic acid-based detection using real time PCR and Standard PCR technology, including ... Key Responsibilities * 65% - Diagnostic Testing * 20% - Lab Management * 10% - Quality Management ...
Manager Nucleic Acid information
What is the difference between Manager Nucleic Acid vs Laboratory Supervisor Nucleic Acid?
| Aspect | Manager Nucleic Acid | Laboratory Supervisor Nucleic Acid |
|---|---|---|
| Credentials | Typically requires a Bachelor's or Master's in Molecular Biology, Biochemistry, or related fields; certifications may include CLIA or CAP | Similar educational background; may also hold certifications in lab safety or specific testing procedures |
| Work Environment | Oversees multiple projects, manages teams, and coordinates testing protocols in a laboratory setting | Supervises daily lab operations, ensures testing accuracy, and manages laboratory staff |
| Employer & Industry Usage | Commonly employed in biotech, healthcare, and research institutions | Found in clinical labs, hospitals, and diagnostic facilities |
While both roles require a strong background in nucleic acid testing, the Manager Nucleic Acid typically has broader responsibilities including strategic planning and team management, whereas the Laboratory Supervisor Nucleic Acid focuses on daily operational supervision and testing accuracy within the lab environment.
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The most popular types of Nucleic Acid jobs in California are:
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For Manager Nucleic Acid jobs in California, the most frequently searched job titles are:
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Research Associate / Senior Research Associate, Nucleic Acids
Berkeley, CA • On-site
Full-time
Posted 14 days ago
Job description
Violet Research Institute (VRI) is building the future of personalized medicine for patients with genetic diseases. We're at the frontier of a new era in medicine - one where treatments can be designed for individual patients based on their unique biology. Recent breakthroughs in science, engineering, and regulatory pathways have made this possible, but much of this work remains nascent and distributed across disparate efforts globally. We're unifying, refining, and scaling these efforts into a cohesive platform. For each patient we serve, we deeply understand their biology, then design and manufacture a targeted treatment that can be delivered in months instead of years.
We combine the urgency and execution mindset of a startup with the mission-driven openness of a nonprofit, allowing us to collaborate broadly and move quickly on behalf of the patients we serve. We've brought together leading researchers, engineers, and organizations across omics, therapeutic design, manufacturing, clinical care, and AI to move from insight to action as quickly as possible.
VRI is founded by the family of our first patient, Violet, and is led by Michael Buckley, Siranush Babakhanova and Steve Turner. Our team is deeply cross-disciplinary and first-principles driven. We value builders, experts, and generalists who are excited to work across domains, challenge conventional approaches, and increase access to personalized medicine.
What We're Looking For
We are hiring a hands-on Research Associate to Senior Research Associate to support molecular biology and assay development for an active therapeutic program. The primary work centers on nucleic acid purification and quantitative PCR (qPCR and digital droplet PCR) used to measure the knockdown efficiency of antisense oligonucleotides (ASOs) against a disease-relevant target. The role also supports cell culture and stem cell differentiation work as needed.
This is an excellent set of hands with a strong track record for clean, reproducible bench work. It is a demanding, fast-paced environment with shifting priorities and frequent new asks, and it offers meaningful contribution to patient-directed science and broad exposure to a growing organization.
What You'll Own
- Extract and purify nucleic acids (RNA and DNA) from cell and tissue samples using standard kits (e.g., Qiagen) and established purification workflows.
- Process human specimens (blood or blood products, CSF, etc) and work safely in a BSC-2 environment.
- Design, run, and analyze qPCR assays on the Applied Biosystems QuantStudio 5 using TaqMan probes and master mix.
- Perform digital droplet PCR (ddPCR) on the Bio-Rad QX600 with the automated droplet generator.
- Quantify ASO knockdown efficiency against target transcripts and report results with clear, well-documented data.
- Maintain rigorous experimental records, assay QC, and data organization to support a rapidly iterating program.
- Contribute to assay scale-up, optimization, and process refinement as capabilities expand.
- Assist with laboratory upkeep such as inventory and supplies stocking.
- Support imaging and microscopy-based readouts on a secondary basis.
- Adapt to changing priorities in a fast-paced, on-site setting.
Minimum Qualifications
- Bachelor's degree in molecular biology, biochemistry, genetics, or a related life science field.
- 2 to 4 years of hands-on laboratory experience in molecular biology and assay development.
- Demonstrated proficiency in nucleic acid purification (RNA and/or DNA) and/or cell harvesting.
- Strong documentation, data analysis, and quality practices, with a proven contamination-control track record.
- Hands-on library preparation and NGS experience.
- Ability to work full-time on-site and thrive in a flexible, high-pace environment.
Preferred Qualifications
- Experience with TaqMan-based qPCR on QuantStudio platforms and Bio-Rad ddPCR (QX600 or comparable).
- Experience with antisense oligonucleotides (ASOs) or other nucleic acid therapeutics.
- Prior industry experience at organizations such as BioMarin, Scribe, Ultragenyx, or similar, or a competitive industry internship (e.g., Genentech).
- Experience with human specimens (i.e. blood or blood products, urine, CSF) and working in a BSC-2 environment.
- Experience with freezer management systems or LIMS.
- Experience with GraphPad Prism or other data analysis and visualization software.
Behavioral Essentials
- Execute independently from loosely specified tasks
- Ask for help only when truly blocked, communicating clearly what's needed
- Thrive in early-stage, ambiguous, high-pace environments
- Mission-driven with genuine care for patient impact