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Manager Downstream Process Development Scientist Jobs in California

This role will partner with Manufacturing, Process Development, Quality, and MSAT teams to analyze downstream purification process data, identify trends, optimize manufacturing performance, and ...

This individual will serve as a subject matter expert in downstream processing, assisting a team of scientists and engineers through process development at bench, pilot, and manufacturing scale. The ...

This individual will serve as a subject matter expert in downstream processing, assisting a team of scientists and engineers through process development at bench, pilot, and manufacturing scale. The ...

Scientist, Cell Line Development

Costa Mesa, CA · On-site

$85K - $116K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

As a Cell Line Development Scientist , you will play a critical role in establishing high ... Partner with Upstream and Downstream Process Development and Analytical teams to deliver integrated ...

Process Development Senior Scientist

Thousand Oaks, CA

$96K - $131K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

... downstream processing for oral solid dosage forms. * Experience supporting oral solid dosage form ... Excellent interpersonal and verbal/written communication skills with demonstrated ability to manage ...

Showing results 21-40

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Infographic showing various Manager Downstream Process Development Scientist job openings in California as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 15% Part Time, and 3% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.

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Posted 20 days ago


Job description

Job Title: Downstream Process Analytics Specialist Industry: Biopharmaceutical CDMO / Biologics Manufacturing Location: Irvine, CA (Onsite) Employment Type: Full-Time Schedule: Monday–Friday | Standard Business Hours (Flexibility for manufacturing support as needed) Position Summary Our client, a growing biopharmaceutical CDMO, is seeking a Downstream Process Analytics Specialist to support commercial and clinical manufacturing operations. This role will partner with Manufacturing, Process Development, Quality, and MSAT teams to analyze downstream purification process data, identify trends, optimize manufacturing performance, and support continuous process improvement initiatives. The ideal candidate will have experience working in a GMP biologics manufacturing environment with downstream purification processes and strong analytical and statistical skills. Essential Responsibilities Analyze manufacturing process data from downstream purification operations, including: Chromatography Tangential Flow Filtration (TFF) Viral Filtration Ultrafiltration/Diafiltration (UF/DF) Monitor critical process parameters (CPPs) and critical quality attributes (CQAs). Perform trend analysis using statistical tools to identify process variability and improvement opportunities. Develop dashboards and reports to communicate manufacturing performance metrics. Support investigations involving deviations, CAPAs, and out-of-trend manufacturing results. Collaborate with Manufacturing, MSAT, Process Development, Validation, and Quality teams to improve process robustness. Evaluate process yield, recovery, cycle time, and resin performance. Generate technical reports and present findings to cross-functional teams. Assist with technology transfers and process characterization studies. Support Continued Process Verification (CPV) and Process Performance Qualification (PPQ) activities. Ensure all documentation complies with GMP, FDA, and ICH guidelines. Qualifications Education Bachelor's degree in: Chemical Engineering Biochemistry Biology Biotechnology Biomedical Engineering Biochemical Engineering KPG123