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Machine Learning Software Engineer Jobs in Illinois

Career Renew

Senior Machine Learning Engineer

Chicago, IL · Remote

$165K - $225K/yr

Career Renew is recruiting for one of its clients a Senior Machine Learning Engineer - this is a ... Knowledge of software engineering best practices including version control (Git) and CI/CD ...

IMC

Hardware Machine Learning Engineer

Chicago, IL · On-site

$200K - $225K/yr

We build the hardware, the software, and the infrastructure, so when you hit a bottleneck, you can ... Understanding of machine learning fundamentals - neural network architectures, inference ...

IMC

Hardware Machine Learning Engineer

Chicago, IL · On-site

$200K - $225K/yr

We build the hardware, the software, and the infrastructure, so when you hit a bottleneck, you can ... Understanding of machine learning fundamentals - neural network architectures, inference ...

Lean Synergy Solutions

Software Engineer

Rockford, IL · On-site

$80K - $120K/yr

Software Engineer Position Summary We are seeking a talented Software Engineer to join a ... Knowledge of machine learning and computer vision concepts. * Experience working with SQL databases ...

Quora

$139K - $168K/yr

At Poe, we use Machine Learning in various parts of the product - bot routing, agent flow, code ... Previous software engineering experience via an internship, work experience, or coding competition

Quora

$139K - $168K/yr

At Poe, we use Machine Learning in various parts of the product - bot routing, agent flow, code ... Previous software engineering experience via an internship, work experience, or coding competition

New

Quora

$139K - $168K/yr

At Poe, we use Machine Learning in various parts of the product - bot routing, agent flow, code ... Previous software engineering experience via an internship, work experience, or coding competition

Quora

$139K - $168K/yr

At Poe, we use Machine Learning in various parts of the product - bot routing, agent flow, code ... Previous software engineering experience via an internship, work experience, or coding competition

New

Quora

$139K - $168K/yr

At Poe, we use Machine Learning in various parts of the product - bot routing, agent flow, code ... Previous software engineering experience via an internship, work experience, or coding competition

Quora

$139K - $168K/yr

At Poe, we use Machine Learning in various parts of the product - bot routing, agent flow, code ... Previous software engineering experience via an internship, work experience, or coding competition

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Showing results 21-40

All JobsMachine Learning Software Engineer JobsMachine Learning Software Engineer Jobs in Illinois

Machine Learning Software Engineer information

See Illinois salary details

$61.5K

$143K

$199.1K

How much do machine learning software engineer jobs pay per year?

As of Jul 24, 2026, the average yearly pay for machine learning software engineer in Illinois is $142,954.00, according to ZipRecruiter salary data. Most workers in this role earn between $116,300.00 and $167,600.00 per year, depending on experience, location, and employer.

What does a Machine Learning Software Engineer do?

A Machine Learning Software Engineer designs, develops, and deploys machine learning models within software applications. They work on data preprocessing, model training, optimization, and integration into production systems. Their role requires expertise in programming (Python, Java, or C++), machine learning frameworks (TensorFlow, PyTorch, or Scikit-learn), and cloud platforms. They collaborate with data scientists and software engineers to build scalable ML solutions.

What are the key skills and qualifications needed to thrive in the Machine Learning Software Engineer position, and why are they important?

To thrive as a Machine Learning Software Engineer, you need a solid understanding of programming (especially Python), algorithms, data structures, and mathematics, ideally backed by a degree in computer science, engineering, or a related field. Experience with frameworks such as TensorFlow or PyTorch, familiarity with cloud platforms (AWS, Azure, or GCP), and relevant certifications in data science or machine learning are highly valuable. Strong problem-solving skills, effective communication, and the ability to work collaboratively with cross-functional teams set outstanding candidates apart. These competencies are crucial for building deployable, scalable, and maintainable machine learning solutions that address real business challenges.

What are the day-to-day responsibilities of a Machine Learning Software Engineer?

As a Machine Learning Software Engineer, your daily tasks typically include developing and optimizing machine learning models, collaborating with data scientists and product teams to define requirements, and integrating models into production systems. You’ll work extensively with large datasets to preprocess, analyze, and validate data, as well as monitor model performance and iterate on solutions when needed. It's common to participate in code reviews, contribute to architectural decisions, and maintain documentation for reproducibility and knowledge sharing. This role offers a dynamic and intellectually stimulating environment, making it ideal for those who enjoy solving complex technical problems and working at the intersection of engineering and data science.

What are the most commonly searched types of Machine Learning Software Engineer jobs in Illinois? The most popular types of Machine Learning Software Engineer jobs in Illinois are:
What are popular job titles related to Machine Learning Software Engineer jobs in Illinois? For Machine Learning Software Engineer jobs in Illinois, the most frequently searched job titles are:
What job categories do people searching Machine Learning Software Engineer jobs in Illinois look for? The top searched job categories for Machine Learning Software Engineer jobs in Illinois are:
What are popular job titles related to Machine Learning Software Engineer jobs in IL? For Machine Learning Software Engineer jobs in IL, the most frequently searched job titles are:
Machine Learning Software Engineer jobs near you
Infographic showing various Machine Learning Software Engineer job openings in Illinois as of July 2026, with employment types broken down into 92% Full Time, 5% Part Time, and 3% Contract. Highlights an 89% Physical, 4% Hybrid, and 7% Remote job distribution, with an average salary of $142,954 per year, or $68.7 per hour.

Senior Machine Learning Engineer

Career Renew

Chicago, IL • Remote

$165K - $225K/yr

Full-time

Posted 2 days ago

Job description

Career Renew is recruiting for one of its clients a Senior Machine Learning Engineer - this is a fully remote role for US/Canada based candidates. Salary range: 165-225K USD yearly plus benefits plus equity.
We are the leading virtual staining company revolutionizing digital pathology adoption worldwide through cutting-edge AI-powered technology. Our solutions deliver diagnostic-quality results in minutes while preserving tissue samples for comprehensive analysis.
Our breakthrough DeepStain™ and ReStain™ technologies enable unlimited virtual staining from a single tissue sample, eliminating the bottlenecks and limitations of traditional chemical staining processes. This innovation supports the critical evolution from research applications to clinical deployment, empowering laboratories to advance their digital pathology capabilities while reducing chemical waste, improving operational efficiency, and expanding diagnostic possibilities.

About the Role

We are seeking an experienced Senior ML Engineer to join our team who owns the representation-learning and generative modeling stack that powers Pictor’s virtual staining. The ideal candidate will have deep expertise in Machine Learning and building generalizable, production-ready models, and evaluations that stand up in clinical workflows.
Design and implement novel computer vision and deep learning algorithms for virtual staining and digital pathology applications
Conduct rigorous experiments to evaluate algorithm performance, validate research hypotheses, and drive iterative improvements
Develop and advance ML models leveraging Vision Transformers, Diffusion Models, GANs, and generative architectures for image-to-image translation tasks
Apply classical and learned image enhancement, denoising, and semantic segmentation techniques to histopathology imaging challenges
Explore image representation in latent space for efficient, high-fidelity virtual staining
Stay current with state-of-the-art research, identifying opportunities to apply novel techniques to PictorLabs’ product roadmap

Collaboration
Collaborate with ML Engineering and software teams to translate research prototypes into production-ready systems meeting latency and throughput requirements
Work with large-scale pathology datasets to train, validate, and fine-tune foundation models and custom architectures
Partner with software engineers, data scientists, and pathology domain experts to integrate research into production systems
Contribute to best practices for data engineering, data governance, and data quality across research and production pipelines
Leverage AI coding and ideation tools to accelerate research velocity and prototype new approaches

Required Qualifications

PhD (preferred) or Master’s degree in Computer Science, Electrical Engineering, or a related field
Deep expertise in computer vision and deep learning, with hands-on experience in one or more of: Vision Transformers, Diffusion Models, GANs, semantic segmentation, or classical image enhancement and denoising
Expert proficiency in Python and PyTorch and other scientific computing environments a plus
Strong mathematical foundation in linear algebra, probability, and optimization
Experience with large-scale model training, distributed computing, or cloud ML infrastructure (AWS, GCP, or Azure)
Knowledge of handling large scale image data, data version controls, model registry, has experience dealing with ML lifecycles
Experience with feature search, data balancing, and data curation pipelines.
Knowledge of software engineering best practices including version control (Git) and CI/CD pipelines
Excellent collaboration and communication skills, with the ability to work effectively in a fast-paced, cross-functional international startup environment
Extensive use of AI tools for coding, optimization, and ideation

Preferred Qualifications

Experience with medical imaging, digital pathology, or whole slide image (WSI) processing
Experience with LoRAs, transformer architecture and state of the art image to image translation models (Flux 2, Z-Image) and the Hugging face ecosystem
Background in generative models and fine-tuning of foundation models
Experience with GPU acceleration and optimization, including CUDA kernel engineering, TensorRT/ONNX export, and inference serving frameworks such as Triton
Experience with hosting computer vision model inference on NVIDIA DGX Spark.
Understanding of FDA regulatory requirements for AI/ML in medical devices
Experience with MLOps tools (MLflow, Kubeflow) and model versioning practices
Develop tools and frameworks to streamline ML research workflows, experimentation, and reproducibility

What We Offer

The opportunity to work on technology that directly improves patient outcomes and transforms clinical diagnostics, alongside a talented team of engineers and researchers pushing the boundaries of AI in healthcare. You will have the freedom to pursue high-impact research while seeing your work deployed at scale in real clinical environments.