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Machine Learning Engineer Jobs in Lexington, MA (NOW HIRING)

Software Machine Learning Engineer

North Reading, MA ยท On-site

$116K - $186K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Opportunity Overview As a Machine Learning Engineer, you will design, develop, and deploy applied AI solutions with a good knowledge on graph machine learning, reinforcement learning, and ...

Machine Learning Engineer II

Cambridge, MA ยท On-site

$106K - $145K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

We are seeking a mid-level Machine Learning Engineer to join our team and help shape the future of Agentic AI systems. This is a hands-on, full-lifecycle (from experimentation to productionization ...

Machine Learning Engineer II

Cambridge, MA

$106K - $145K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

We are seeking a mid-level Machine Learning Engineer to join our team and help shape the future of Agentic AI systems. This is a hands-on, full-lifecycle (from experimentation to productionization ...

Lead Machine Learning Engineer

Cambridge, MA ยท On-site

$112K - $147K/yr

Lead Machine Learning Engineer At Capital One, we are changing banking for good by creating responsible and reliable AI-powered systems. Our investments in technology infrastructure and world-class ...

Lead Machine Learning Engineer

Cambridge, MA

$112K - $147K/yr

Lead Machine Learning Engineer At Capital One, we are changing banking for good by creating responsible and reliable AI-powered systems. Our investments in technology infrastructure and world-class ...

Machine Learning Engineer, Data Mining

Boston, MA ยท On-site +1

$144K - $192K/yr

As a Machine Learning Engineer on the Data Mining team, your mission is to help build the "Brain" of this engine. You will work with state-of-the-art foundation models to extract insights from ...

Machine Learning Engineer, Data Mining

Boston, MA ยท On-site

$144K - $192K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

As a Machine Learning Engineer on the Data Mining team, your mission is to help build the "Brain" of this engine. You will work with state-of-the-art foundation models to extract insights from ...

Machine Learning Engineer, Data Mining

Boston, MA ยท On-site +1

$144K - $192K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

As a Machine Learning Engineer on the Data Mining team, your mission is to help build the "Brain" of this engine. You will work with state-of-the-art foundation models to extract insights from ...

Senior Machine Learning Engineer

Boston, MA ยท On-site

$170K - $205K/yr

  • PTO

About the position: We're looking for a Senior Machine Learning Engineer with deep expertise in some area of ML engineering to join our growing ML team and work closely with our software and computer ...

Senior Machine Learning Engineer

Boston, MA ยท On-site +1

$161K - $246K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Overview: The ASUS Robotics & AI Center is seeking a Senior Machine Learning Engineer to join our global research and development team. This role centers on leading the design and delivery of ...

Senior Machine Learning Engineer

Boston, MA ยท Remote

$140K - $190K/yr

By joining our team as a Senior Machine Learning Engineer , you will play a pivotal role in building cutting-edge AI products that directly impact how new therapies reach patients. We're looking for ...

Showing results 41-60

Machine Learning Engineer information

See Lexington, MA salary details

$35.4K

$144.7K

$217.4K

How much do machine learning engineer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for machine learning engineer in Lexington, MA is $144,677.00, according to ZipRecruiter salary data. Most workers in this role earn between $114,000.00 and $174,100.00 per year, depending on experience, location, and employer.

What is a machine learning engineer?

Machine Learning Engineers are specialized software engineers who design, build, and deploy machine learning models and systems. They work at the intersection of software engineering and data science, transforming data-driven prototypes into scalable, production-ready solutions. Their responsibilities include data preprocessing, model selection, algorithm implementation, and optimizing models for performance and efficiency. Machine Learning Engineers often collaborate with data scientists, software developers, and other stakeholders to integrate AI technologies into products and services.

What does a machine learning engineer do?

A machine learning engineer maintains production systems and often works with other engineers. In this career, you work with software development methodology, use modern software development tools, and use agile practices. You also play a role in software design and architecture, so you may occasionally work with a programmer. An engineer may help to predict how a model should perform or seek out regression issues by using different test types and algorithms. To fulfill your duties and responsibilities, you work on a computer and use an array of skills and programs to carry out these tests.

What are the key skills and qualifications needed to thrive as a machine learning engineer, and why are they important?

To thrive as a Machine Learning Engineer, you need strong programming skills (particularly in Python), a solid background in mathematics and statistics, and a degree in computer science or a related field. Experience with machine learning frameworks (such as TensorFlow or PyTorch), data processing tools, and cloud platforms is typically required. Problem-solving ability, effective communication, and adaptability are crucial soft skills for collaborating with teams and translating complex models into practical solutions. These competencies ensure the development, deployment, and continual improvement of machine learning systems that drive business value.

What are some common challenges faced by machine learning engineers when deploying models to production?

Machine Learning Engineers often encounter challenges such as ensuring model scalability, maintaining data consistency between training and production environments, and monitoring model performance over time. Integrating models into existing software infrastructure may require collaboration with DevOps and software engineering teams to address issues like latency, version control, and resource allocation. Additionally, ongoing model maintenance is crucial to prevent model drift and ensure that predictions remain accurate as new data becomes available.

What is the difference between Machine Learning Engineer vs Data Scientist?

AspectMachine Learning EngineerData Scientist
CredentialsBachelor's or Master's in CS, Data Science, or related; experience with ML frameworksBachelor's or Master's in Statistics, Data Science, or related; strong analytical skills
Work EnvironmentDevelops scalable ML models, deploys algorithms into productionAnalyzes data, builds models, interprets data insights
Industry UsageTech companies, startups, AI-focused firmsFinance, healthcare, marketing, research organizations

While both roles work with data and machine learning, Machine Learning Engineers focus on building and deploying scalable ML models in production environments. Data Scientists primarily analyze data, create models, and generate insights. The roles often overlap but differ in their core responsibilities and focus areas.

What job categories do people searching Machine Learning Engineer jobs in Lexington, MA look for?

The top searched job categories for Machine Learning Engineer jobs in Lexington, MA are:

What cities near Lexington, MA are hiring for Machine Learning Engineer jobs?

Cities near Lexington, MA with the most Machine Learning Engineer job openings:

Infographic showing various Machine Learning Engineer job openings in Lexington, MA as of August 2026, with employment types broken down into 1% As Needed, 75% Full Time, 21% Part Time, and 3% Contract. Highlights an 88% Physical, 2% Hybrid, and 10% Remote job distribution, with an average salary of $144,677 per year, or $69.6 per hour.

Machine Learning Engineer - Computational Drug Discovery

4:59 NewCo, a 5AM Ventures Company

Watertown, MA โ€ข On-site

Full-time

Re-posted 14 days ago


Job description

Job Summary:
4:59 NewCo, a 5AM Ventures Company, is focused on developing a pipeline of small molecules to address unmet clinical needs. The Machine Learning Engineer will work at the intersection of machine learning research and experimental teams, ensuring that models transition from research to production effectively.
Responsibilities:
โ€ข Own and maintain production machine learning infrastructure, ensuring models developed by the research team are robust, maintainable, and deployable
โ€ข Develop computational tools, data pipelines, and machine learning systems that support scientific workflows across chemistry and biology
โ€ข Collaborate closely with chemists and biologists to understand requirements and translate them into effective software solutions
โ€ข Design and build internal AI agents and automation systems, with substantial opportunity to define both the technical direction and user experience
โ€ข Write clean, well-tested, version-controlled code and contribute to a strong engineering culture through code review and technical collaboration
Qualifications:
Required:
โ€ข Bachelorโ€™s or Masterโ€™s degree in Computer Science, Chemistry, Physics, Data Science, or a related technical field
โ€ข Strong software engineering fundamentals, including code quality, testing, version control, and CI/CD practices
โ€ข Hands-on experience developing machine learning systems using PyTorch
โ€ข Familiarity with undergraduate-level organic chemistry; you do not need to be a chemist, but should be comfortable working with molecular structures and chemical concepts
โ€ข Ability to communicate effectively with scientific collaborators from non-programming backgrounds
โ€ข Strong sense of ownership and the ability to independently drive ambiguous projects from concept to completion
โ€ข We are particularly excited to bring in people who enjoy turning research ideas into tools that scientists actually use. The ideal candidate is comfortable operating across disciplines, takes pride in building reliable systems, and appreciates the opportunity to have a direct impact on scientific decision-making.
Preferred:
โ€ข Experience with AWS, MLflow, SQL, Polars, pandas, Ray, or scikit-learn
โ€ข Familiarity with LLM tooling, AI agents, or agent development frameworks
โ€ข Background in cheminformatics, computational biology, bioinformatics, or related fields
โ€ข Experience working in a startup, research, or other highly iterative technical environment
Company:
4:59 is a hands-on internal effort of 5AM Ventures to discover, incubate, and fund breakthrough science. Founded in , the company is headquartered in Boston, MA, US, , with a team of 11-50 employees. The company is currently Early Stage.