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Machine Learning Computational Biology Jobs (NOW HIRING)

Manifold Bio

AI/ML Research Engineer

Boston, MA · On-site

Required : • Bachelor's or Master's degree in Computer Science, Machine Learning, Computational Biology, or related field • 2+ years of hands-on experience with PyTorch and/or JAX for deep ...

Manifold Bio

AI/ML Research Engineer

Boston, MA · On-site

Required : • Bachelor's or Master's degree in Computer Science, Machine Learning, Computational Biology, or related field • 2+ years of hands-on experience with PyTorch and/or JAX for deep ...

Manifold Bio

AI/ML Research Engineer

Boston, MA · On-site

Required : • Bachelor's or Master's degree in Computer Science, Machine Learning, Computational Biology, or related field • 2+ years of hands-on experience with PyTorch and/or JAX for deep ...

insitro

(Senior) ML Scientist

South San Francisco, CA · On-site

$183K - $238K/yr

Ph.D. in computer science, machine learning, computational biology, systems biology, or a related discipline. * Extensive hands on experience developing ML methods for biological data modalities

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Machine Learning Computational Biology information

What types of projects might I work on as a Machine Learning Computational Biology specialist?

As a Machine Learning Computational Biology specialist, you may work on projects ranging from analyzing large-scale genomic data to developing predictive models for disease risk or drug response. Typical tasks include designing and implementing machine learning algorithms to identify patterns in biological datasets, collaborating with biologists and clinicians to interpret results, and contributing to publications or presentations. You'll often be part of a multidisciplinary team, interacting with data scientists, laboratory researchers, and software engineers. This role offers the opportunity to work on cutting-edge biomedical research and have a direct impact on advancements in healthcare and life sciences.

What is a Machine Learning Computational Biology job?

A Machine Learning Computational Biology job involves applying machine learning techniques to analyze biological data, such as genomics, proteomics, and medical imaging. Professionals in this field develop algorithms and models to identify patterns, make predictions, and generate insights that can drive scientific discovery or improve healthcare. They typically work with large datasets, employing statistical and computational methods to solve complex biological problems. The role often requires expertise in programming, data science, and domain-specific biological knowledge. It is commonly found in academia, pharmaceutical companies, biotech firms, and healthcare institutions.

What are the key skills and qualifications needed to thrive in the Machine Learning Computational Biology position, and why are they important?

To thrive as a Machine Learning Computational Biology professional, you need a strong background in biology, statistics, computer science, and machine learning, typically supported by an advanced degree in a relevant field. Familiarity with programming languages such as Python or R, experience with bioinformatics tools, and knowledge of machine learning frameworks like TensorFlow or scikit-learn are commonly required. Strong analytical thinking, effective communication, and the ability to work collaboratively in interdisciplinary teams are highly valued soft skills. These qualifications are essential for solving complex biological problems, developing robust computational models, and effectively communicating findings to both technical and non-technical stakeholders.

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Machine Learning Computational Biology jobs near you
Infographic showing various Machine Learning Computational Biology job openings in the United States as of June 2026, with employment types broken down into 76% Full Time, and 24% Part Time. Highlights an 87% Physical, 2% Hybrid, and 11% Remote job distribution.
Junior Computational Biologist (Remote)

Junior Computational Biologist (Remote)

Astrix Inc

South San Francisco, CA • On-site, Remote

$30 - $34/hr

Full-time

Posted 17 days ago

Job description

Pay Rate Low: 30 | Pay Rate High: 34
A leading biotechnology research organization is seeking a Junior Computational Biologist to support efforts in refining how cellular states are quantified and validated!
Title: Jr. Computational Biologist (Remote Contract)
Location: Remote (Must be available during PST business hours)
Compensation: $30-34/hour + benefits
Contract Duration: 6-12+ months
Job Duties:
This project will focus on benchmarking functional scoring methodologies and improving interpretability of high-dimensional transcriptomic datasets.
The selected candidate will contribute to distinguishing true biological signal from technical variation in large-scale single-cell atlases, directly enhancing the reliability of automated cell-state classification frameworks.
Start Date: July 1, 2026
  • Duration: Through December 18, 2026
  • Commitment: Full-time (100%)
  • Ideal Candidate: Upcoming June 2026 PhD graduate or recent PhD graduate
  • Location: Onsite in South San Francisco, CA preferred; remote within the U.S. considered (must work PST hours)
  • Visa Sponsorship: Not availabl

Key Responsibilities
  • Systematically evaluate and benchmark computational approaches for quantifying phenotype activation across single-cell transcriptomic datasets.
  • Establish rigorous statistical baselines and negative-control frameworks to improve the robustness of automated cell-state classification methods.
  • Develop or refine computational methods to address limitations in current approaches.
  • Design strategies to distinguish genuine biological signatures from stochastic or technical noise.
  • Present findings in internal scientific reviews and contribute to potential conference abstracts or peer-reviewed publications.

Required Qualifications
  • Extensive hands-on experience in single-cell data analysis using Scanpy, AnnData, and Pandas.
  • Strong proficiency implementing statistical and machine learning models using scikit-learn and SciPy.
  • Demonstrated commitment to reproducible research practices and well-organized code.
  • Ability to clearly communicate complex computational concepts to interdisciplinary scientific teams.
  • Master's degree with ongoing PhD pursuit, or recent PhD graduate, in Computational Biology, Computer Science, Machine Learning, or related quantitative discipline.
  • Interest in drug discovery and comfort working in dynamic, research-driven environments.

Preferred Qualifications
  • Background knowledge in cell biology and/or immunology.
  • Experience with hypothesis testing, noise modeling, and benchmarking computational tools.
  • Familiarity with Explainable AI (XAI) approaches or large-scale biological datasets.
  • Demonstrated ability to build or extend novel bioinformatics pipelines.
    INDBH
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