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Machine Learning Computational Biology Jobs in California

insitro

(Senior) ML Scientist

South San Francisco, CA · On-site

$183K - $238K/yr

Ph.D. in computer science, machine learning, computational biology, systems biology, or a related discipline. * Extensive hands on experience developing ML methods for biological data modalities

NewLimit

Computational Biologist

South San Francisco, CA · On-site

$150K - $200K/yr

... and machine learning models to unravel the biology of epigenetic aging and disease using ... Description NewLimit is seeking a Computational Biologist to join our Predict team. In this role ...

NewLimit

Computational Biologist

South San Francisco, CA · On-site

$150K - $200K/yr

... and machine learning models to unravel the biology of epigenetic aging and disease using ... Description NewLimit is seeking a Computational Biologist to join our Predict team. In this role ...

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Machine Learning Computational Biology information

What is a machine learning computational biology?

A Machine Learning Computational Biology job involves applying machine learning techniques to analyze biological data, such as genomics, proteomics, and medical imaging. Professionals in this field develop algorithms and models to identify patterns, make predictions, and generate insights that can drive scientific discovery or improve healthcare. They typically work with large datasets, employing statistical and computational methods to solve complex biological problems. The role often requires expertise in programming, data science, and domain-specific biological knowledge. It is commonly found in academia, pharmaceutical companies, biotech firms, and healthcare institutions.

What types of projects might I work on as a machine learning computational biology specialist?

As a Machine Learning Computational Biology specialist, you may work on projects ranging from analyzing large-scale genomic data to developing predictive models for disease risk or drug response. Typical tasks include designing and implementing machine learning algorithms to identify patterns in biological datasets, collaborating with biologists and clinicians to interpret results, and contributing to publications or presentations. You'll often be part of a multidisciplinary team, interacting with data scientists, laboratory researchers, and software engineers. This role offers the opportunity to work on cutting-edge biomedical research and have a direct impact on advancements in healthcare and life sciences.

What are the key skills and qualifications needed to thrive in the machine learning computational biology position, and why are they important?

To thrive as a Machine Learning Computational Biology professional, you need a strong background in biology, statistics, computer science, and machine learning, typically supported by an advanced degree in a relevant field. Familiarity with programming languages such as Python or R, experience with bioinformatics tools, and knowledge of machine learning frameworks like TensorFlow or scikit-learn are commonly required. Strong analytical thinking, effective communication, and the ability to work collaboratively in interdisciplinary teams are highly valued soft skills. These qualifications are essential for solving complex biological problems, developing robust computational models, and effectively communicating findings to both technical and non-technical stakeholders.

What are popular job titles related to Machine Learning Computational Biology jobs in California?

For Machine Learning Computational Biology jobs in California, the most frequently searched job titles are:

What job categories do people searching Machine Learning Computational Biology jobs in California look for?

The top searched job categories for Machine Learning Computational Biology jobs in California are:

What cities in California are hiring for Machine Learning Computational Biology jobs?

Cities in California with the most Machine Learning Computational Biology job openings:

Machine Learning Computational Biology jobs near you
Infographic showing various Machine Learning Computational Biology job openings in California as of August 2026, with employment types broken down into 1% As Needed, 80% Full Time, 18% Part Time, and 1% Contract. Highlights an 87% Physical, 2% Hybrid, and 11% Remote job distribution.

Co-Op, ML Scientist for Protein Engineering

Lila Sciences

San Francisco, CA • On-site

Full-time

Re-posted 19 days ago

Job description

Your Impact at LILA

Lila is embarking on a transformative mission to redefine the future of medicine by combining automated large-scale data generation with scientific superintelligence. At Lila, we don't just use AI to analyze biology; we are building the loop where AI and automation co-evolve to solve the hardest problems in medicine.

To this end, the Life Science AI team is developing machine learning systems that can reason over biological data and help design better biomolecules. We are seeking an ML Scientist Co-Op to contribute to protein engineering research, including problems related to generative protein design, antibody engineering, developability, and wet-lab-informed model iteration.

This is an opportunity to work alongside Lila scientists on applied ML research at the interface of AI and biology. You will help explore models, datasets, and workflows that connect computational protein design ideas to real experimental needs, gaining hands-on experience in a fast-moving scientific environment.

What You'll Be Building

  • Contribute to ML research projects focused on protein engineering, antibody design, and related biomolecule design problems.
  • Explore generative and predictive modeling approaches for protein sequence, structure, function, and developability.
  • Work with scientists and ML researchers to translate biological design goals into tractable computational problems.
  • Analyze biological and experimental datasets to identify patterns, evaluate model outputs, and guide design decisions.
  • Prototype workflows that connect model predictions, candidate prioritization, and wet-lab feedback.
  • Communicate results clearly through code, notebooks, written summaries, and presentations to scientific and technical collaborators.

What You'll Need to Succeed

  • Currently enrolled as a PhD student in Computer Science, Machine Learning, Computational Biology, Bioengineering, Biophysics, or a related quantitative field.
  • Research experience in machine learning, computational biology, protein engineering, or a closely related area.
  • Strong programming skills in Python and experience with modern ML frameworks such as PyTorch, JAX, or similar tools.
  • Ability to work with biological sequence, structure, assay, or other scientific datasets.
  • Interest in applying ML methods to real biological design problems in partnership with experimental scientists.
  • Clear communication skills and comfort working in a collaborative, cross-disciplinary research environment.

Bonus Points For

  • Experience with protein language models, structure prediction, generative protein design, diffusion or flow-based models, or antibody design.
  • Familiarity with protein structure, biophysics, developability, affinity maturation, or wet-lab validation concepts.
  • Publications, preprints, open-source work, or research projects in ML for biology, protein engineering, or AI for Science.
  • Experience building active learning, model evaluation, or data analysis workflows for scientific discovery.
  • Comfort collaborating with experimental scientists and translating between ML concepts and biological constraints.

Apply