... to assist our scientists in both pRED and gRED to deliver more innovative and transformative ... We are seeking a Principal Machine Learning Engineer to join our Foundation Models team. In this ...
... to assist our scientists in both pRED and gRED to deliver more innovative and transformative ... We are seeking a Principal Machine Learning Engineer to join our Foundation Models team. In this ...
... to assist our scientists in both pRED and gRED to deliver more innovative and transformative ... We are seeking a Principal Machine Learning Engineer to join our Foundation Models team. In this ...
New
... to assist our scientists in both pRED and gRED to deliver more innovative and transformative ... We are seeking a Principal Machine Learning Engineer to join our Foundation Models team. In this ...
New
Staff Machine Learning Engineer - Music Mission
New York, NY · On-site
$227K - $324K/yr
As a Staff Machine Learning Engineer, you'll help shape the Machine Learning technical strategy for ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Staff Machine Learning Engineer - Music Mission
New York, NY · On-site
$227K - $324K/yr
As a Staff Machine Learning Engineer, you'll help shape the Machine Learning technical strategy for ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Staff Machine Learning Engineer - Music Mission
New York, NY · Remote
$227K - $324K/yr
As a Staff Machine Learning Engineer, you'll help shape the Machine Learning technical strategy for ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Quick apply
Staff Machine Learning Engineer - Music Mission
New York, NY · Remote
$227K - $324K/yr
As a Staff Machine Learning Engineer, you'll help shape the Machine Learning technical strategy for ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Machine Learning Engineer/Senior Machine Learning Engineer - Devops, AI for Drug Discovery
New York, NY · On-site
$142K - $182K/yr
... to assist our scientists in both pRED and gRED to deliver more innovative and transformative ... What you'll do Machine Learning Engineer - DevOps * Design, implement, and maintain scalable and ...
Machine Learning Engineer/Senior Machine Learning Engineer - Devops, AI for Drug Discovery
New York, NY · On-site
$142K - $182K/yr
... to assist our scientists in both pRED and gRED to deliver more innovative and transformative ... What you'll do Machine Learning Engineer - DevOps * Design, implement, and maintain scalable and ...
Machine Learning Engineer/Senior Machine Learning Engineer - Devops, AI for Drug Discovery
Manhattan, NY · On-site
$143K - $184K/yr
... to assist our scientists in both pRED and gRED to deliver more innovative and transformative ... What you'll do Machine Learning Engineer - DevOps * Design, implement, and maintain scalable and ...
Machine Learning Engineer/Senior Machine Learning Engineer - Devops, AI for Drug Discovery
Manhattan, NY · On-site
$143K - $184K/yr
... to assist our scientists in both pRED and gRED to deliver more innovative and transformative ... What you'll do Machine Learning Engineer - DevOps * Design, implement, and maintain scalable and ...
Machine Learning Engineer (LLM / Personalization)
Manhattan, NY · On-site
$61.50 - $81.25/hr
Role Overview As a Machine Learning Engineer reporting to the LLM Research Lead, you will operate ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Machine Learning Engineer (LLM / Personalization)
Manhattan, NY · On-site
$61.50 - $81.25/hr
Role Overview As a Machine Learning Engineer reporting to the LLM Research Lead, you will operate ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Machine Learning Engineer
$62K - $100K/yr
Write high-quality, production-ready code and assist in code reviews to maintain standards of excellence. * Develop and implement comprehensive testing protocols, including smoke tests and unit tests ...
Machine Learning Engineer
$62K - $100K/yr
Write high-quality, production-ready code and assist in code reviews to maintain standards of excellence. * Develop and implement comprehensive testing protocols, including smoke tests and unit tests ...
We're seeking a Staff Machine Learning Engineer to build and scale foundational ML systems that ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
We're seeking a Staff Machine Learning Engineer to build and scale foundational ML systems that ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Staff Machine Learning Engineer - Policy & Safety
New York, NY · On-site
$227K - $324K/yr
What You Will Do * Build and scale machine learning systems for proactive content detection ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Staff Machine Learning Engineer - Policy & Safety
New York, NY · On-site
$227K - $324K/yr
What You Will Do * Build and scale machine learning systems for proactive content detection ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Machine Learning Research Engineer New
Manhattan, NY · On-site
$226K/yr
... machine learning. Our ongoing investment in top engineering talent and technology ensures our ... Take your validated insights to assist engineering teams with platform improvements and advise ...
Machine Learning Research Engineer New
Manhattan, NY · On-site
$226K/yr
... machine learning. Our ongoing investment in top engineering talent and technology ensures our ... Take your validated insights to assist engineering teams with platform improvements and advise ...
Senior Machine Learning Engineer, Personalization, Muse
New York, NY · On-site +1
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Senior Machine Learning Engineer, Personalization, Muse
New York, NY · On-site +1
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Machine Learning Engineer
Livingston, NJ · On-site
$62K - $100K/yr
Write high-quality, production-ready code and assist in code reviews to maintain standards of excellence. * Develop and implement comprehensive testing protocols, including smoke tests and unit tests ...
Machine Learning Engineer
Livingston, NJ · On-site
$62K - $100K/yr
Write high-quality, production-ready code and assist in code reviews to maintain standards of excellence. * Develop and implement comprehensive testing protocols, including smoke tests and unit tests ...
Senior Machine Learning Engineer, Personalization, Muse
New York, NY · On-site
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Senior Machine Learning Engineer, Personalization, Muse
New York, NY · On-site
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Senior Machine Learning Engineer, Personalization, Muse
New York, NY · Remote
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Quick apply
Senior Machine Learning Engineer, Personalization, Muse
New York, NY · Remote
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Senior Machine Learning Engineer - Policy & Safety
$184K - $262K/yr
Working at the intersection of machine learning, platform engineering, and regulatory compliance ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Quick apply
Senior Machine Learning Engineer - Policy & Safety
$184K - $262K/yr
Working at the intersection of machine learning, platform engineering, and regulatory compliance ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Senior Machine Learning Engineer - Policy & Safety
New York, NY · On-site
$184K - $262K/yr
Working at the intersection of machine learning, platform engineering, and regulatory compliance ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Senior Machine Learning Engineer - Policy & Safety
New York, NY · On-site
$184K - $262K/yr
Working at the intersection of machine learning, platform engineering, and regulatory compliance ... These tools assist our recruitment team but do not replace human judgment. Final hiring decisions ...
Senior Machine Learning Engineer, Personalization, Muse
Manhattan, NY · On-site
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... We have ways to request reasonable accommodations during the interview process and help assist in ...
Senior Machine Learning Engineer, Personalization, Muse
Manhattan, NY · On-site
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... We have ways to request reasonable accommodations during the interview process and help assist in ...
Senior Machine Learning Engineer, Personalization, Muse
Manhattan, NY · On-site
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... We have ways to request reasonable accommodations during the interview process and help assist in ...
Senior Machine Learning Engineer, Personalization, Muse
Manhattan, NY · On-site
$184K - $262K/yr
You'll join a team working at the intersection of machine learning, music understanding, and user ... We have ways to request reasonable accommodations during the interview process and help assist in ...
Assistant General Counsel, Product (Data Products, Machine Learning & Artificial Intelligence) @ Abr
Manhattan, NY · On-site
Powering Deeper Understanding in HealthcareTransforming Medical Conversations with Responsible AI Abridge is seeking an Associate General Counsel, Product (Data Products, Machine Learning ...
Assistant General Counsel, Product (Data Products, Machine Learning & Artificial Intelligence) @ Abr
Manhattan, NY · On-site
Powering Deeper Understanding in HealthcareTransforming Medical Conversations with Responsible AI Abridge is seeking an Associate General Counsel, Product (Data Products, Machine Learning ...
Machine Learning Assistant information
What is a machine learning assistant?
What are the key skills and qualifications needed to thrive as a machine learning assistant?
What are some common challenges a machine learning assistant may face when supporting data preparation and model training?
What are the most commonly searched types of Machine Learning jobs in New York?
The most popular types of Machine Learning jobs in New York are:
What are popular job titles related to Machine Learning Assistant jobs in New York?
For Machine Learning Assistant jobs in New York, the most frequently searched job titles are:
What job categories do people searching Machine Learning Assistant jobs in New York look for?
The top searched job categories for Machine Learning Assistant jobs in New York are:
What cities in New York are hiring for Machine Learning Assistant jobs?
Cities in New York with the most Machine Learning Assistant job openings:

Principal Machine Learning Engineer, Foundation Models, AI for Drug Discovery
New York, NY • On-site
Full-time
Posted 4 days ago
Genentech rating
8.8
Based on 22 frontline employees who took The Breakroom Quiz
12th of 86 rated pharmaceutical
Job description
Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche's Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
The Opportunity:
At Roche's AI for Drug Discovery (AIDD) group (Prescient Design), we are revolutionizing drug discovery with cutting-edge machine learning. We are seeking a Principal Machine Learning Engineer to join our Foundation Models team. In this role, you will drive the engineering, scaling, and operationalization of our internal reasoning Large Language Models (LLMs) and agentic systems, enabling them to succeed at complex biomolecular design and autonomous scientific workflows.
You will work at the intersection of engineering and research, spanning the full stack: from the agent orchestration logic that makes these systems scientifically useful, to the distributed infrastructure and MLOps/AgentOps that make them robust at scale.
In this role, you will:
- Own the MLOps/AgentOps Stack for Foundation Models: Establish rigorous evaluation harnesses that check agent output against scientific ground truth, and the experiment tracking, system observability and monitoring, CI/CD, and infrastructure those systems depend on.
- Agentic Systems Engineering: Architect and deploy autonomous agents that utilize tools, retrieve scientific evidence, and execute multi-step reasoning across drug discovery workflows. Design and implement advanced agent memory architectures and context management for long-horizon scientific tasks. Build reliable interfaces between agents and genomic, chemical, and clinical data sources.
- Scalable ML Systems & Productionization: Design, build, and optimize large-scale distributed training and inference systems for foundation models. Own the production Python/PyTorch codebases that turn fast-moving research into enterprise-grade software.
- Technical Strategy & Leadership: Define the long-term engineering roadmap for AI4DD's agentic and foundation models. Serve as a technical authority on ML infra for Genentech leadership, architect cross-functional platforms, and elevate the engineering bar across gRED.
- Research-to-Production Translation: Partner closely with ML Scientists and domain experts to translate open-ended scientific problems and complex reasoning objectives into scoped, shippable, and highly efficient systems.
Who You Are:
- Education & Experience: BS, MS, or PhD in Computer Science, Machine Learning, Engineering, or a related quantitative field. You have a demonstrated track record of technical leadership with increasing levels of experience based on degree: PhD with 5+ years, MS with 8+ years, or BS with 10+ years of industry experience building, shipping, and owning large-scale ML systems and infrastructure end-to-end.
- Engineering Foundation: Exceptional Python programming skills and rigorous software engineering fundamentals (Git, automated testing, CI/CD, documentation, architecture design).
- Deep Learning & Distributed Systems: Extensive hands-on experience with modern deep learning frameworks (PyTorch, JAX) and deploying ML infrastructure on AWS or HPC environments, including distributed training tools.
- Agentic Systems: Practical experience designing agent orchestration frameworks (e.g., LangGraph, MCP-based tool integration), managing persistent agent memory, and building self-improving loops.
- Domain Interest: Strong passion for applying frontier AI and agentic science to AI for Drug Discovery (AI4DD), biology, and chemistry.
Preferred Qualifications:
- Inference-Time Optimization: Deep expertise in LLM serving, test-time compute, sampling/search strategies, model routing, batching, caching, and latency/cost/quality tradeoffs.
- Scientific Context: Experience working with molecular modalities (e.g., protein sequences, chemical graphs, and structured molecular data).
- Open Source: A public portfolio of significant technical contributions to open-source ML, systems, or MLOps libraries.
Onsite presence on our campus is expected in compliance with Roche/Genentech policy.
Relocation benefits are not available for this job posting.
The expected salary range for this position based on the primary location of New York is $192,500 - $357,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
#ComputationCoE
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
What Genentech employees say
Pay
Benefits
Hours and flexibility
Workplace
Get the full story on Breakroom
About Genentech
Sourced by ZipRecruiter
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
Industry
Scientific research and development services
Company size
10,000+ Employees
Headquarters location
South San Francisco, CA, US
Year founded
1976