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Linker Jobs (NOW HIRING)

MacroGenics

Scientist I/II - Bioconjugation

Rockville, MD · On-site

$100 - $125/hr

Synthesize, and optimize novel linker-payload molecules, directly contributing to next-generation ADC therapies. * Purify, characterize, and analyze synthesized molecules using analytical techniques ...

Scorpion Therapeutics

NY · On-site

Plus: knowledge of latest synthetic methods for antibody-conjugate linker generation; familiarity with peptidomimetics or antibody-targeted therapeutics. * Plus: general understanding of biological ...

Horicon Elementary

STEAM and PE Teacher

Annapolis, CA · On-site

$52K - $68K/yr

STEAM and PE Teacher at Horicon Elementary Share on X Print Application Deadline 12/5/2026 11:55 PM Pacific Date Posted 8/19/2026 Contact Celeste Linker 707.886.5322 101 Number of Openings Not ...

Dyne Tx

$115K - $140K/yr

D evelops and evaluates novel conjugation strategies, linker technologies, and site-specific modification approaches. * Purifies and characterizes bioconjugates using chromatographic, spectroscopic ...

Biopharma Careers

Director, Bioconjugation

Virginia, MN · On-site

This role will lead a team of bioconjugation scientists and set the conjugation strategy while partnering with Chemistry on linker-payload design across a portfolio spanning small molecule cytotoxic ...

New

Russell, Tobin & Associates

Golang developer

Almont, CO · On-site

$47 - $52/hr

Investigate compiler, linker, build, test, and runtime failures * Troubleshoot applicable CI and presubmit failures * Validate that upgraded packages successfully build and existing tests pass

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Linker information

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$116.7K

$185K

How much do linker jobs pay per year?

As of Sep 9, 2026, the average yearly pay for linker in the United States is $116,743.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,000.00 and $126,500.00 per year, depending on experience, location, and employer.

What is a linker?

Linkers are specialized software tools used in computer programming to combine various pieces of code and data into a single executable program. They take object files generated by compilers and resolve references between them, connecting code and libraries as needed. Linkers can handle static linking, where code is combined at compile time, or dynamic linking, where code is linked at runtime. This process is essential for creating functional applications from modular code components.

What are some common challenges linkers face when coordinating between production teams and software developers?

Linkers often act as intermediaries, ensuring that all components of a software build process are correctly integrated. A key challenge is managing communication across teams with different technical backgrounds, which can lead to misunderstandings about requirements or timelines. Additionally, Linkers must stay organized to track dependencies and resolve conflicts efficiently, especially when multiple updates happen simultaneously. Strong collaboration skills and attention to detail are essential for overcoming these challenges and ensuring smooth project delivery.

What are the key skills and qualifications needed to thrive as a linker, and why are they important?

To thrive as a Linker (typically referring to a software linker), you need strong knowledge of programming languages, computer architecture, and compiler design, usually supported by a degree in computer science or a related field. Familiarity with build systems, version control tools like Git, and scripting languages is essential, along with experience using linker tools such as GNU ld or Microsoft Link. Attention to detail, problem-solving abilities, and effective communication are crucial soft skills for diagnosing and resolving integration issues. These skills are vital for ensuring that software components are correctly combined, dependencies are managed, and applications run efficiently and reliably.

What is the difference between Linker vs Assembler?

AspectLinkerAssembler
Primary RoleCombines object files into a single executableConverts assembly language into machine code
Required SkillsKnowledge of linking process, file formats, and programmingUnderstanding of assembly language and hardware architecture
Work EnvironmentSoftware development, build processesLow-level programming, embedded systems
Common UsageFinal step in software compilationWriting performance-critical code

The main difference between a Linker and an Assembler is their role in software development. An Assembler translates assembly language into machine code, while a Linker combines multiple object files into a single executable. Both are essential in the software build process but serve distinct functions at different stages.

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What states have the most Linker jobs?

States with the most job openings for Linker jobs include:

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For Linker jobs, the most frequently searched job titles are:

Linker jobs near you
Infographic showing various Linker job openings in the United States as of September 2026, with employment types broken down into 96% Full Time, 2% Contract, and 2% Nights. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $116,743 per year, or $56.1 per hour.

Senior / Principal Scientist, ADC Conjugation Process Development

Bothell, WA • On-site

Immunome, Inc.
Biotechnology Research and Development • 11 - 50 employees
Learn more about Immunome, Inc.external

Full-time

Re-posted 28 days ago

Job description

Company Overview
Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.
Position Overview
We are seeking an experienced and motivated Senior/Principal Scientist in ADC Conjugation Process Development to support our growing pipeline. This role will be responsible for the optimization of critical conjugation and purification process parameters for ADC Drug Substance (DS) Development. The preferred candidate will coordinate and execute strategies from milligram to multi-gram scales, including tox/GMP batches, while demonstrating practical expertise in different methodologies and purification strategies for clinical and commercial-stage ADC DS manufacturing. The ideal candidate will have experience with technology transfer, regulatory compliance, and coordination with CDMO partners at GMP manufacturing facilities. A strong working knowledge of different conjugation technologies and cytotoxic linker-payloads is essential, as is experience with standard analytical and characterization approaches used for both biologics and ADCs.
Responsibilities
  • Implement and execute ADC Conjugation Process Development (PD) strategies, including Design of Experiment (DOE) and One Factor at a Time (OFAT) approaches for critical reaction parameters.
  • Oversee the progression of ADC batch sizes from milligram to >100 g scales to support not only PD optimization, but analytical and formulation development, DS/DP stability studies, and in vivo experiments (including critical GLP tox studies) for both IND- and BLA-stage activities.
  • Lead the multi-gram scale purification optimization for both antibody intermediates and ADCs via ultrafiltration/diafiltration (UF/DF), and, if required, preparative chromatography or other approaches.
  • Fulfill role as ADC DS subject matter expert (SME) on both internal cross-functional CMC teams and for external CDMO partners to ensure alignment on ADC program goals, deliverables, and objectives. Occasional travel to advise and oversee Development and GMP manufacturing processes will be expected.
  • Prepare essential documentation (SOPs, protocols, and reports) to support tech transfers, GMP activities, and regulatory submissions for clinical development and commercialization.
  • Stay current with emerging trends, innovations, and regulatory requirements for ADC DS, integrating necessary or potentially beneficial features into our internal company strategies and workflows.
  • Lead/support authoring and reviewing of relevant module 3 sections of regulatory submissions (IND, IMPD, BLA, etc.), along with, if necessary, responding to information requests and interfacing with global health authorities.

Qualifications
  • A Bachelors, Masters, or Ph.D. degree in Chemistry, Chemical/Biochemical Engineering, Biotechnology, or a related field.
  • A minimum of 5 years of biotech/biopharma industry experience with a Ph.D., 8 years with a Master's, or 10 years with a Bachelor's degree, or equivalent experience. An ADC or Conjugation/Bioconjugation Process Development focus is required.
  • Demonstrated success with the development and scale-up of different ADC conjugation technologies and strategies, including a proven ability to work with a variety of different small molecule linker-payloads and antibody intermediate materials. Expected expertise in relevant laboratory operations and equipment necessary for successful execution of development activities.
  • Prior experience with tech transfer, external CDMO engagement (encompassing both Development and GMP manufacturing activities), and internal coordination with relevant cross-functional teams.

Knowledge and Skills
  • A strong understanding of the common conjugation, purification, analytical, and characterization approaches used for ADCs, with a solid foundation in overcoming some of the challenges encountered in these workflows.
  • Expertise in tangential flow filtration (TFF) at the multi-gram scale for the efficient removal of unreacted linker-payloads and to provide a stable ADC DS formulation.
  • Good working knowledge of standard analytical and characterization techniques used for ADCs including, but not limited to, SEC, HIC, and RP U/HPLC chromatographic methods in addition to LC-MS, icIEF, and CE-SDS strategies for biomolecules and related conjugates.
  • Knowledge of GMP standards and regulatory guidelines, with experience supporting IND, INDa, and BLA submissions.
  • The ability to manage multiple projects simultaneously while being able to prioritize and balance hands-on tasks with strategic responsibilities.
  • Exceptional communication skills, with an emphasis on effective collaborations with both internal stakeholders and external partners.

Washington State Pay Range
$146,000-$188,000 USD
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
E-Verify
Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish).

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