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Lcms Operator Jobs (NOW HIRING)

Sr. Engineer - LCMS

Boston, MA · On-site

$55 - $60/hr

Experience repairing, troubleshooting, supporting and operating analytical chemistry or related equipment required * Minimum 7 years experience with life science laboratory equipment (e.g. LC, LC/MS ...

Sr. Engineer - LCMS

Boston, MA · On-site

$55 - $60/hr

Experience repairing, troubleshooting, supporting and operating analytical chemistry or related equipment required * Minimum 7 years experience with life science laboratory equipment (e.g. LC, LC/MS ...

... to departmental Standard Operating Procedures. 7. Monitor, operate, and troubleshoot ... Experience with Mass Spec, HPLC, and LCMS are highly preferred * Molecular or Analytical Chemistry ...

... to departmental Standard Operating Procedures. 7. Monitor, operate, and troubleshoot ... Experience with Mass Spec, HPLC, and LCMS are highly preferred * Molecular or Analytical Chemistry ...

Media Technician Non GXP

North Brunswick, NJ · On-site

$20 - $26.50/hr

Proven experience operating analytical laboratory equipment such as HPLC, LCMS, liquid handlers, or similar instrumentation. * Strong understanding of laboratory safety protocols and experience ...

... operator responsible for LCMS instrumentation, Hamilton liquid handling system, and ancillary laboratory equipment to perform and urine and oral fluid toxicology testing. • Review and certify ...

Metrologist Validation

Ilchester, MD · On-site

$90K - $140K/yr

Validation Metrologist LCMS GCMS - Ilchester, MD Validation Metrologist Calibration Technician ... and Standard Operating Procedures related technical writing. • Train junior metrologists.

Experience in operation and maintenance of HPLC, LCMS, and flash chromatography. * Knowledge of ... Other responsibilities may include maintaining equipment inventories, operating analytical and ...

Showing results 21-40

Lcms Operator information

See salary details

$10

$23

$37

How much do lcms operator jobs pay per hour?

As of Aug 10, 2026, the average hourly pay for lcms operator in the United States is $23.04, according to ZipRecruiter salary data. Most workers in this role earn between $18.03 and $21.88 per hour, depending on experience, location, and employer.

What is an LCMS operator?

LCMS Operators are professionals who operate Liquid Chromatography-Mass Spectrometry (LC-MS) instruments, which are used to analyze chemical compounds in a variety of samples. They are responsible for preparing samples, running the LC-MS equipment, maintaining the instruments, and interpreting data to ensure accurate results. LCMS Operators often work in laboratories within industries such as pharmaceuticals, environmental science, food safety, and forensics. Their expertise is crucial for identifying and quantifying chemical substances in research and quality control processes.

What are some common challenges LCMS operators face when troubleshooting instrument performance issues?

LCMS Operators often encounter challenges such as inconsistent results, signal instability, or unexpected background noise during routine analyses. These issues may stem from factors like contaminated solvents, worn-out columns, or clogged ion sources. Successful troubleshooting typically involves methodically checking each component, maintaining detailed logs, and collaborating closely with analytical chemists and maintenance teams. Staying up to date with manufacturer protocols and regular preventive maintenance are key to minimizing downtime and ensuring reliable data generation.

What is the difference between Lcms Operator vs Analytical Chemist?

AspectLcms OperatorAnalytical Chemist
Required CredentialsAssociate degree or relevant certification, training in chromatographyBachelor's degree in chemistry or related field, often with advanced certifications
Work EnvironmentLaboratory setting, operating chromatography instrumentsLaboratory, research, and development environments, performing complex analyses
Employer & Industry UsagePharmaceutical, biotech, environmental testing labsPharmaceutical, chemical manufacturing, research institutions
Common Search & ComparisonOften compared for entry-level roles in labsMore research-focused, higher education requirements

The main difference between an Lcms Operator and an Analytical Chemist lies in their responsibilities and qualifications. Lcms Operators typically handle instrument operation and basic data collection, requiring less advanced education. Analytical Chemists perform complex analyses, interpret data, and often hold higher degrees. Both roles are vital in laboratory settings, but they differ in scope and expertise.

What are the key skills and qualifications needed to thrive as an LCMS operator?

To thrive as an LCMS Operator, you need a solid background in analytical chemistry, attention to detail, and experience with laboratory practices, often supported by a degree in chemistry or a related field. Familiarity with liquid chromatography-mass spectrometry (LC-MS) instruments, data analysis software, and relevant quality control protocols is essential. Strong problem-solving skills, organization, and effective communication help you troubleshoot issues and collaborate with team members. These skills and qualifications ensure accurate sample analysis, reliable data, and efficient laboratory operations.
More about Lcms Operator jobs
Infographic showing various Lcms Operator job openings in the United States as of August 2026, with employment types broken down into 70% Full Time, 20% Part Time, and 10% Contract. Highlights an 100% In-person job distribution, with an average salary of $47,930 per year, or $23 per hour.

Senior Scientist, Oligo Chemistry

Danaher

Sunnyvale, CA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 22 days ago


Danaher rating

7.7

Company rating: 7.7 out of 10

Based on 29 frontline employees who took The Breakroom Quiz


Job description

Bring more to life.

Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?

At Integrated DNA Technologies (IDT), one of Danaher's 15+ operating companies, our work saves lives-and we're all united by a shared commitment to innovate for tangible impact.

You'll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher's system of continuous improvement, you help turn ideas into impact - innovating at the speed of life.

Our team at Integrated DNA Technologies (IDT), is united by a commitment to collaboration and scientific excellence, building on a strong foundation of innovation, expertise, and reliability. Guided by our vision to help researchers rapidly move from the lab to life-changing advances, we work closely with global partners to accelerate progress and genomics breakthroughs across fields like cancer, infectious disease, rare genetic disorders, and more. At IDT, you'll be part of a culture rooted in continuous learning and improvement-where your growth fuels our mission to accelerate the pace of genomics and helps shape a healthier, brighter future for all.

Learn about the Danaher Business System which makes everything possible.

The Senior Scientist, Oligo Chemistry is responsible for contributing hands-on scientific expertise to the development, optimization, and characterization of oligonucleotide synthesis processes. The ideal candidate brings deep experience in organic chemistry-particularly phosphoramidite chemistry-and strong analytical skills, including high-resolution LCMS, to support high-quality oligo production and continuous process improvement. The position plays a critical role in advancing core technology platforms, enabling new products and services, and driving scientific and commercial impact across the organization.

This position reports to the Director of Emerging Technologies and is part of the Emerging Technologies Team located in Sunnyvale, CA and will be an on-site role.

In this role, you will have the opportunity to:

  • Design, execute, and optimize oligonucleotide synthesis workflows with a strong focus on phosphoramidite chemistry and solidphase synthesis
  • Apply organic chemistry principles to improve synthesis efficiency, yield, and product quality
  • Develop and optimize post-synthesis process steps, including cleavage, deprotection, and purification (e.g., cartridge, HPLC, or other relevant methods), utilizing highresolution mass spectrometry (LCMS) and complementary analytical techniques to assess oligo identity, purity, and failure modes
  • Contribute to evaluation and implementation of new reagents, chemistries, or process improvements for oligo synthesis platforms
  • Other duties as assigned.

The essential requirements of the job include:

  • Bachelor's degree in chemistry, organic chemistry, biochemistry, or a related discipline; advanced degree (M.S. or Ph.D.) preferred.
  • Minimum of 5+ years of handson laboratory experience in oligonucleotide synthesis or closely related chemistry
  • Strong practical expertise in phosphoramidite chemistry and solidphase oligo synthesis along with a track record of safe laboratory practices
  • Demonstrated experience using LCMS (highresolution preferred) to characterize oligos and diagnose synthesis or process issues
  • Proven experience optimizing synthesis or downstream process steps, including cleavage, deprotection, and purification


Travel & Physical/Environment Requirements:

  • Ability to travel 10% time domestic and international
  • Ability to occasionally lift, move or carry equipment up to 10lb
  • Ability to frequently work in a laboratory environment for extended periods

It would be a plus if you also possess previous experience in:

  • Background in high-throughput biology, automation, and NGS-based analysis.
  • Working with prototype instrumentation and collaborating with engineers.
  • Environmental health and safety coordination work.

IDT, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it's a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at Danaher Benefits Info.

The annual salary range OR the hourly range for this role is $135,000-$160,000. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future.

This job is also eligible for bonus/incentive pay.

We offer comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law.

Join our winning team today. Together, we'll accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.


For more information, visit www.danaher.com.


Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.


The U.S. EEO posters are available here.


For candidates who are based outside of New York City or who are applying for roles outside of New York City, for more information about conditions of any job offer please click here.


We comply with federal and state disability laws and make reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact:1-202-419-7762 or applyassistance@danaher.com.


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About Danaher

Sourced by ZipRecruiter

We are a science and technology innovator committed to helping our customers solve complex challenges, and improving quality of life around the world. A global family of more than 20 operating companies, we drive meaningful innovation in some of today's most dynamic, growing industries.

Industry

Medical equipment and supplies manufacturing

Company size

10,000+ Employees

Headquarters location

Washington, DC, US

Year founded

1984