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Instrumentation Software Engineer Jobs (NOW HIRING)

Type One Energy

Software Engineer I&C

Knoxville, TN · On-site

The Software Engineer - Instrumentation & Control (I&C) will design, develop, and maintain advanced control systems supporting next-generation stellarator technologies. This role focuses on ...

Actalent

Software Engineer

Ogden, UT

$60 - $80/hr

Troubleshoot software issues and diagnose problems with test instrumentation in an engineering environment. * Collaborate closely with cross-functional teams, including test, hardware, and production ...

Actalent

Software Engineer

Tucson, AZ · On-site

$60 - $80/hr

Troubleshoot software issues and diagnose problems with test instrumentation in an engineering environment. * Collaborate closely with cross-functional teams, including test, hardware, and production ...

Actalent

Software Engineer

Tucson, AZ · On-site

$60 - $80/hr

Troubleshoot software issues and diagnose problems with test instrumentation in an engineering environment. * Collaborate closely with cross-functional teams, including test, hardware, and production ...

Actalent

Software Engineer

Tucson, AZ

$60 - $80/hr

Troubleshoot software issues and diagnose problems with test instrumentation in an engineering environment. * Collaborate closely with cross-functional teams, including test, hardware, and production ...

Actalent

Software Engineer

Tucson, AZ

$60 - $80/hr

Troubleshoot software issues and diagnose problems with test instrumentation in an engineering environment. * Collaborate closely with cross-functional teams, including test, hardware, and production ...

UNAVAILABLE

Software Developer

Kirkland, WA · On-site

$71K - $127K/yr

Being one of the world's leading analytical instrumentation companies, Bruker is strongly committed ... The Bruker AXS-Electron Microscopy division currently has an opening for a Software Developer to ...

Bruker

Software Developer

Kirkland, WA · On-site

$71K - $127K/yr

Being one of the world's leading analytical instrumentation companies, Bruker is strongly committed ... The Bruker AXS-Electron Microscopy division currently has an opening for a Software Developer to ...

Applied Materials

Software Engineer

Santa Clara, CA · On-site

$179K - $246K/yr

About the Role We are seeking a highly capable and driven Software Engineer with a strong instrumentation background to serve as the Technical Lead for the Software Platform of our wafer processing ...

Amat

Software Engineer

Santa Clara, CA

$179K - $246K/yr

About the Role We are seeking a highly capable and driven Software Engineer with a strong instrumentation background to serve as the Technical Lead for the Software Platform of our wafer processing ...

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All JobsInstrumentation Software Engineer Jobs

Instrumentation Software Engineer information

See salary details

$12.5K

$104.9K

$164K

How much do instrumentation software engineer jobs pay per year?

As of Jun 24, 2026, the average yearly pay for instrumentation software engineer in the United States is $104,896.00, according to ZipRecruiter salary data. Most workers in this role earn between $77,500.00 and $131,500.00 per year, depending on experience, location, and employer.

What are Instrumentation Software Engineers?

Instrumentation Software Engineers are professionals who design, develop, and maintain software systems that interface with measurement and control instruments. They write code to collect, process, and analyze data from sensors and equipment, often in fields like manufacturing, scientific research, or industrial automation. Their work ensures that complex instruments operate accurately and reliably, often integrating hardware and software components. They also troubleshoot software issues and optimize systems for performance and reliability.

What is instrumentation in software engineering?

In software engineering, instrumentation refers to the process of adding code or tools to a software system to monitor, measure, and analyze its performance, behavior, or usage. Instrumentation is often used by instrumentation software engineers to facilitate debugging, optimize performance, and ensure system reliability, typically involving tools like logging frameworks, profiling tools, and performance monitors.

Is instrumentation in high demand?

Instrumentation Software Engineers are in high demand in industries such as manufacturing, energy, and aerospace, where precise control and data acquisition are critical. The role often requires knowledge of programming languages like C or Python and familiarity with control systems and automation tools, making skilled professionals valuable in these sectors.

What engineers make $500,000?

Highly experienced engineers in specialized fields such as software engineering, petroleum engineering, or aerospace engineering can earn $500,000 or more annually, often through a combination of base salary, bonuses, and stock options. Senior roles requiring advanced skills, certifications, and leadership responsibilities tend to have the highest compensation levels.

How does an Instrumentation Software Engineer typically collaborate with hardware and test engineering teams during a project?

Instrumentation Software Engineers work closely with hardware and test engineering teams throughout the project lifecycle. They often participate in cross-functional meetings to understand hardware specifications, define software requirements, and ensure seamless integration between software and physical instruments. Regular communication is essential to troubleshoot issues, validate data acquisition, and optimize system performance. This collaborative approach helps deliver robust, reliable solutions that meet both technical and project goals.

What is the difference between Instrumentation Software Engineer vs Control Systems Engineer?

AspectInstrumentation Software EngineerControl Systems Engineer
Required CredentialsBachelor's in Software, Electrical, or Mechanical Engineering; knowledge of programming languagesBachelor's in Electrical, Mechanical, or Control Engineering; knowledge of control theory and programming
Work EnvironmentDevelops software for instrumentation devices in manufacturing, testing, or automationDesigns and implements control systems in industrial processes or automation
Industry UsageUsed in manufacturing, automation, and testing industriesCommon in industrial automation, process control, and manufacturing sectors

Both roles involve working with automation and control systems, but Instrumentation Software Engineers focus on developing software for instrumentation devices, while Control Systems Engineers design and optimize entire control processes. The roles often overlap but differ in scope and focus.

How much does Microsoft pay instrumentation engineers?

Instrumentation Software Engineers at Microsoft typically earn between $100,000 and $150,000 annually, depending on experience, location, and level. Compensation may also include bonuses, stock options, and benefits, with senior roles earning higher salaries. Skills in automation, control systems, and programming are often valued in this role.

What are the key skills and qualifications needed to thrive as an Instrumentation Software Engineer, and why are they important?

To thrive as an Instrumentation Software Engineer, you need a strong background in computer science, electronics, and instrumentation engineering, usually with a relevant degree. Familiarity with programming languages (such as Python, C++, or LabVIEW), data acquisition systems, and industry-specific protocols is vital, and certifications in software development or instrumentation can be advantageous. Strong problem-solving abilities, attention to detail, and effective communication skills help you excel in multidisciplinary teams and troubleshoot complex systems. These competencies are crucial for developing reliable software solutions that interface with hardware, ensuring precise measurement and control in technical environments.
More about Instrumentation Software Engineer jobs
What states have the most Instrumentation Software Engineer jobs? States with the most job openings for Instrumentation Software Engineer jobs include:
What job categories do people searching Instrumentation Software Engineer jobs look for? The top searched job categories for Instrumentation Software Engineer jobs are:
Instrumentation Software Engineer jobs near you
Infographic showing various Instrumentation Software Engineer job openings in the United States as of June 2026, with employment types broken down into 93% Full Time, and 7% Part Time. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $104,896 per year, or $50.4 per hour.
Instrument Control Software Engineer

Instrument Control Software Engineer

Ansa Biotechnologies

Emeryville, CA • On-site

$147K - $178K/yr

Full-time

Medical, Dental, Vision

Posted 8 days ago

Job description

Our mission at Ansa Biotechnologies is to revolutionize the way we make DNA. Compared to reading or editing life's code, writing new code from scratch has remained one of the field's most elusive challenges. At Ansa, we are putting nature to work, creating novel enzymatic solutions that will redefine how we build DNA. We believe that the biggest challenges our world faces will be solved using biotechnology and that DNA synthesis is the fuel for that transformation. Our enzyme-based approach (published in Nature Biotechnology) promises to dramatically accelerate innovation in biological research and biotechnology, including therapeutics, diagnostics, biomanufacturing, and synthetic biology. We look forward to our DNA products making an impact.
About the Role
We are seeking a versatile Instrument Control Software Engineer to architect and develop the software backbone of our custom hardware systems. This role is a bridge between complex scientific discovery and robust engineering-you will translate high-level research goals into high-performance, production-ready instrument control systems.
The ideal candidate thrives in an interdisciplinary environment where software, chemistry, and high-precision automation intersect. You are as comfortable discussing fluidics requirements with a scientist as you are finding a race condition in a serial communication library.
We are looking for someone who is curious, adaptable, and excited to learn. We don't expect you to have experience in every single item listed, but if you are enthusiastic about the prospect of gaining that experience in a highly collaborative environment, you are exactly who we want to talk to. We value engineers who are proactive, resourceful, and ready to contribute to success across the entire product lifecycle.
Key Responsibilities
  • Software Architecture & Development: Design, build, and test production-grade software for custom in-house instrumentation using C# and WPF.
  • Requirement Translation: Act as the technical liaison for the scientific team; extract user needs and translate them into formal software and functional requirement specifications.
  • Hardware Integration: Develop interfaces for off-the-shelf and custom hardware using third-party APIs, SDKs, and .NET wrappers.
  • Full-Stack Ownership: Take ownership of the software lifecycle, from gathering requirements to maintaining documentation and tracking progress in Jira.
  • Collaborative Innovation: Work closely with mechanical and electrical engineers, scientists and manufacturing staff to debug hardware/software interfaces and ensure seamless system integration.
Required Qualifications
  • Education: Bachelor's degree in Computer Science, Computer Engineering, Mechanical Engineering, or a related technical field.
  • Experience: 5-8+ years in software engineering with a proven track record of developing software that controls physical hardware.
  • Core Tech Stack: Advanced proficiency in C#, .NET; experience with WPF is a plus.
  • Instrumentation: Direct experience building custom instrumentation software and integrating with third party devices.
Preferred Skills
  • Sensor Selection & Integration: Proven ability to evaluate and integrate sensors (pressure, flow, optical, encoders) based on requirements, signal-to-noise ratios, and chemical compatibility.
  • Communication Protocols: Hands-on experience implementing drivers for communicating with third party devices with RS232, RS485, CAN or vendor provided libraries
  • Data & Persistence: Experience with Entity Framework Core (EF Core) and relational database design (SQL) for run-history logging and telemetry.
  • Embedded: Experience developing firmware for embedded devices in C or C++ for the STM32 family of chipsets
  • Vision Inspection: Familiarity with vision inspection using tools like OpenCV or Cognex VisionProElectrical: Familiarity with reading electrical schematics and ability to troubleshoot electrical systems
  • Regulatory & Process: Professional experience working within a formal V&V framework, including maintaining traceability matrices and version-controlled documentation.
  • Testing: Experience developing automated test benches to validate sensor accuracy and system reliability.

What We Offer
  • Competitive salary and equity.
  • Generous benefits package including health, dental, and vision.
  • Ongoing professional development and training opportunities.
  • A collaborative and innovative work environment.
  • The opportunity to be part of a company at the forefront of synthetic biology and innovation.

San Francisco Bay Area Pay Range
$147,000 - $178,000
Ansa Biotechnologies is an Equal Opportunity Employer.
All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
At Ansa, we're building a community of intelligent and passionate humans that will help us change biotechnology research with our enzymatic DNA synthesis technology. We believe that challenging and trusting one another, and continuously learning are essential to our success. We believe that building diverse, inclusive and psychologically safe spaces are essential to a community culture that yields the happiest colleagues and friends, and the highest quality research.
As we are growing rapidly, this is an ever present goal: hiring the best people while building diversity in thought, experience and background within our team. While the biotechnology space can feel limited in BIPOC, non-binary and even female representation, we endeavor to make hiring decisions that will continue to grow and support our team in the direction of cultural diversity and sustainability.

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