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Infrastructure Engineer Jobs in Portland, OR (NOW HIRING)

Genentech

ITOT Infrastructure Engineer

Hillsboro, OR · On-site

$95K - $176K/yr

As IT OT Infrastructure Engineer, you will be responsible for the local Manufacturing Infrastructure and act as the key contact for the Global IT Teams delivering and operating the Global ...

TSMC

IT Infrastructure Engineer

Camas, WA · On-site

The IT Infrastructure Engineer will manage and optimize core infrastructure systems, focusing on Oracle/DB2 databases and enhancing operational automation capabilities. Responsibilities : • Design ...

TSMC

IT Infrastructure Engineer

Camas, WA

We are looking for an IT Infrastructure Engineer, this role will be responsible for the comprehensive management, maintenance, and optimization of our core infrastructure systems, with a strong focus ...

TSMC

IT Infrastructure Engineer

Camas, WA · On-site

We are looking for an IT Infrastructure Engineer, this role will be responsible for the comprehensive management, maintenance, and optimization of our core infrastructure systems, with a strong focus ...

Deloitte

Infrastructure Engineer - Cloud

Portland, OR · On-site

$114K - $149K/yr

... Infrastructure (T&I) team. We are insatiably curious and life-long learners focused on technology ... The Cloud Engineer will work within Deloitte Cloud Framework to implement security controls and ...

Collabera

Infrastructure Systems Engineer 4

Portland, OR

$114K - $149K/yr

As an Infrastructure Middleware Engineer you will help set the direction for the various environments in partnership with the Enterprise Architects and our Developer community. You will work with ...

Panthalassa

Senior Compute Infrastructure Engineer

Portland, OR · On-site

$115K - $156K/yr

Our internal computing infrastructure and software applications are fundamental to the operation of ... Experience deploying and maintaining engineering-focused software (e.g. Siemens NX, Ansys, other CA ...

Panthalassa

Senior Compute Infrastructure Engineer

Portland, OR · On-site

$115K - $156K/yr

Our internal computing infrastructure and software applications are fundamental to the operation of ... Experience deploying and maintaining engineering-focused software (e.g. Siemens NX, Ansys, other CA ...

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Showing results 1-20

All JobsInfrastructure Engineer JobsInfrastructure Engineer Jobs in Portland, OR

Infrastructure Engineer information

See Portland, OR salary details

$49.3K

$134.8K

$193.1K

How much do infrastructure engineer jobs pay per year?

As of Jul 28, 2026, the average yearly pay for infrastructure engineer in Portland, OR is $134,808.00, according to ZipRecruiter salary data. Most workers in this role earn between $114,000.00 and $149,600.00 per year, depending on experience, location, and employer.

What engineers make $200,000 a year?

Senior infrastructure engineers, cloud engineers, and site reliability engineers often earn $200,000 or more annually, especially with extensive experience, specialized skills in cloud platforms like AWS or Azure, and relevant certifications. These roles typically involve managing large-scale systems, automation, and security in complex IT environments.

What do infrastructure engineers do?

Infrastructure engineers design, implement, and maintain the hardware, networks, and systems that support an organization’s IT environment. They work with servers, cloud services, and networking equipment, often using tools like virtualization and automation to ensure system reliability and security. Strong problem-solving skills and knowledge of networking protocols, operating systems, and security are essential for this role.

What are Infrastructure Engineers?

Infrastructure Engineers are IT professionals responsible for designing, building, managing, and maintaining the foundational technology systems that support organizations. This includes servers, networks, storage, virtualization, and cloud resources. Their main goal is to ensure a reliable, secure, and scalable infrastructure that enables business operations and supports application needs. They often collaborate with other IT teams to implement new technologies, troubleshoot issues, and optimize system performance.

What engineers make $300,000 a year?

Senior infrastructure engineers, cloud engineers, and site reliability engineers with extensive experience, specialized skills, and certifications such as AWS or Google Cloud can earn $300,000 or more annually. These roles often require advanced knowledge of networking, automation, and large-scale system management, typically in high-demand industries or organizations with complex infrastructure needs.

What are some common challenges Infrastructure Engineers face when managing large-scale systems?

Infrastructure Engineers often encounter challenges such as ensuring system scalability, maintaining high availability, and minimizing downtime during updates or incidents. Managing complex environments requires balancing security, performance, and cost efficiency while supporting rapid growth or changes in business needs. Effective communication and collaboration with development, security, and operations teams are also crucial to address issues quickly and maintain seamless service delivery.

What are the key skills and qualifications needed to thrive as an Infrastructure Engineer, and why are they important?

To thrive as an Infrastructure Engineer, you need a solid understanding of networking, operating systems, cloud platforms, and infrastructure architecture, often supported by a degree in computer science or related fields. Familiarity with tools like AWS, Azure, VMware, automation frameworks (e.g., Ansible, Terraform), and relevant certifications such as AWS Certified Solutions Architect or CompTIA Network+ is typical. Strong problem-solving, communication, and teamwork skills help you collaborate across IT and business units and respond effectively to incidents. These skills and qualities are crucial for ensuring system reliability, security, and scalability in complex technology environments.

What is the difference between Infrastructure Engineer vs Network Engineer?

AspectInfrastructure EngineerNetwork Engineer
CertificationsCompTIA Network+, Cisco CCNA, Cisco CCNPCompTIA Network+, Cisco CCNA, Cisco CCNP
Work EnvironmentData centers, cloud environments, enterprise IT infrastructureNetwork operations centers, enterprise networks, ISP environments
ResponsibilitiesDesigning, implementing, maintaining IT infrastructure, servers, cloud systemsDesigning, configuring, troubleshooting network hardware and connectivity
Industry UsageIT companies, cloud providers, large enterprisesTelecommunications, ISPs, large organizations with complex networks

While both roles require similar certifications and work in enterprise environments, Infrastructure Engineers focus on overall IT infrastructure including servers and cloud systems, whereas Network Engineers specialize in network hardware and connectivity. Understanding these differences helps in choosing the right career path or job search focus.

What engineers make $500,000?

Senior infrastructure engineers, especially those with extensive experience, specialized skills in cloud platforms, and certifications like AWS or Cisco, can earn $500,000 or more annually. High compensation is often associated with leadership roles, working in large organizations, or consulting positions with significant responsibilities.

What Is an Infrastructure Engineer?

An infrastructure engineer ensures that their organization’s computer network infrastructure functions properly. As an infrastructure engineer, you monitor computer systems, improve IT applications, and troubleshoot infrastructure problems. Exact job responsibilities vary widely depending on the employer, but typical duties involve working with storage and hosting technologies, monitoring computer software and hardware, installing servers, and developing cloud-based infrastructure. Infrastructure engineer positions are available in all industries, especially those with a heavy reliance on technology. This career requires extensive experience working with computers and the ability to stay current with emerging technologies and trends.

More about Infrastructure Engineer jobs
What are the most commonly searched types of Infrastructure Engineer jobs in Portland, OR? The most popular types of Infrastructure Engineer jobs in Portland, OR are:
What are popular job titles related to Infrastructure Engineer jobs in Portland, OR? For Infrastructure Engineer jobs in Portland, OR, the most frequently searched job titles are:
What job categories do people searching Infrastructure Engineer jobs in Portland, OR look for? The top searched job categories for Infrastructure Engineer jobs in Portland, OR are:
Infrastructure Engineer jobs near you
Infographic showing various Infrastructure Engineer job openings in Portland, OR as of July 2026, with employment types broken down into 95% Full Time, and 5% Contract. Highlights an 78% In-person, 5% Hybrid, and 17% Remote job distribution, with an average salary of $134,808 per year, or $64.8 per hour.
ITOT Infrastructure Engineer

ITOT Infrastructure Engineer

Genentech, Inc.

Hillsboro, OR • On-site

$95K - $176K/yr

Full-time

Posted 12 days ago

Genentech rating

8.8

Company rating: 8.8 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

11th of 86 rated pharmaceutical

Job description

The Opportunity
The ITOT Infrastructure position offers a unique opportunity to shape the information and technology solutions in alignment with Pharma Manufacturing. Reporting to the ITOT System Operations and Infrastructure Lead, you will be a member of the ITOT Manufacturing Network and deliver Globally harmonized IT and OT solutions for the global PT network.
As IT OT Infrastructure Engineer, you will be responsible for the local Manufacturing Infrastructure and act as the key contact for the Global IT Teams delivering and operating the Global Infrastructure. In partnering with the site your focus is always on Manufacturing Production Make Assess Release (MAR) in alignment with site priorities as well as demand originating from Projects.
Key Responsibilities:
  • Manage ITOT Infrastructure for Manufacturing System Platforms including IMS, MES , DCS, SCADA and other Control Systems.
  • Site ITOT Infrastructure Support Coordinator with Global Infrastructure solutions at site (e.g. support of Active Directory and firewall policies to allow proper access and communication).
  • Lead and/or provide support for the evaluation, installation, and maintenance of Manufacturing infrastructure including installation and upgrade of control systems hardware, software, control networks, user administration, database administration, security, system monitoring, backup and recovery of Microsoft Windows Server Operating Systems and SQL Databases.
  • Implement Robust Disaster Recovery Solutions.
  • Lead and/or support implementation of ITOT infrastructure standards and best practices across all Site ITOT and Process Automation platforms, working with other process automation engineers, IT and OT professionals.
  • Support commissioning and startup activity of new process control systems and manufacturing systems (Syncade (will be replaced with PharmaSuite) , DeltaV, OSI PI historian, etc).
  • Be the go to Infrastructure expert at the site who bridges the gap between Automation and underlying Storage Compute and Network infrastructure.
  • Execute control system virtualization administration, user administration, system monitoring, capacity planning, design, installation, configuration, and upgrade of platform.
  • Execute computer system validation and control system lifecycle management.
  • Support the integration of Edge Computing and IIoT gateways to facilitate real-time data flow to the OSI PI Historian and cloud-based analytics.
  • Partner with the Cyber Security Engineer to implement Zero Trust architectures and robust security measures.
  • Support data backup, recovery management, and disaster recovery plans and exercise on manufacturing infrastructure.
  • Triage, troubleshoot, and resolve ServiceNow Trouble Ticket Incident, Requests, and Problems associated with manufacturing infrastructure.

Who You Are
  • Bachelor's degree in Engineering, Computer Science, or equivalent experience.
  • A minimum of 7 years systems engineer experience involved in the design, implementation, and/or support of automation systems, preferably in a regulated (Pharmaceutical) industry.
  • 24X7 environment, participate in an on-call environment to meet business continuity requirements, including weekends and holidays as required.
  • Strong understanding and experience working with OT Manufacturing Infrastructure, security management, Automation Control Systems, and data backup technologies.
  • Experience working in a change control environment, computer systems validation, and Good Manufacturing Practice (GMP) documentation.
  • Experience with various Operating Systems, Storage, Backup, Application and Infrastructure Monitoring, Virtualization, LAN/WAN, Firewalls, RDBMS, Client-server and terminal virtualization as a System Administrator.
  • Advanced expertise in VMware or Nutanix for managing virtualized control system workloads.
  • Experience with Composable Infrastructure, Next Gen Antivirus EDR/XDR technologies, and Composable Infrastructure.
  • Experience with High Availability (HA) Failover Clustering and Redundancy.
  • Experience with Microsoft SQL Server installation, troubleshooting, and tuning.
  • Experience with Microsoft Active Directory and group policy configuration.
  • Familiarity with Orchestration tools like Terraform, Ansible or puppet for automated infrastructure provisioning is a plus.
  • Certifications: Microsoft Certified System Engineer (MCSE, Cisco Certified Network Associate (CCNA), VMware Certified Advanced Professional (VCAP), Certified Information System Security Professional (CISSP), ISA/IEC 62443 Cybersecurity Specialist certification, Global Industrial Cyber Security Professional (GICSP) is a plus.
  • Strong technical writing, verbal communication, interpersonal and problem-solving skills.
  • Strong analytical skills for effective troubleshooting and problem solving.

The expected salary range for this position based on the primary location of Oregon is $95,200 - $176,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are not available for this job posting.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

What Genentech employees say

Pay

Benefits

Hours and flexibility

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About Genentech

Sourced by ZipRecruiter

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

South San Francisco, CA, US

Year founded

1976

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