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In Vitro Assay Scientists Jobs (NOW HIRING)

Astrix Inc

In Vitro Scientist III

Ridgefield, CT · On-site

$49 - $54/hr

The company is looking for In Vitro Scientist III to join the team. This is an amazing opportunity ... Design, develop, validate, and execute in vitro assays to study lymphocyte (B cell and T cell ...

Crown Bioscience, Inc.

This role oversees global assay platforms, multi-site scientific teams, operational strategy, and capability expansion across cell-based, immunology, imaging-based, and translational in vitro systems.

CYNET SYSTEMS

Scientist III

Ridgefield, CT · On-site

$49/hr

... Science, Genomics, Biostatistics or Bioinformatics preferred) OR Bachelor's degree from an ... Conduct routine and non-routine cellular assays to support in vitro assay development.

Eurofins

In Vitro Scientist

New Brunswick, NJ · On-site

$25 - $35/hr

Creates and maintains lab assay schedule. * Leads training of In Vitro Scientists. * Other duties as assigned. Qualifications * B.S. degree or equivalent experience in laboratory animal medicine ...

Cogent Scientific

Expert In Vitro Biologist

Manhattan, NY · On-site

$110K - $125K/yr

... scientific answers. * Establish and optimize novel in vitro assays using 3D organotypic models, complex co-cultures, organoids, transwell systems, air-liquid interface, and/or organ-on-a-chip ...

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How much do in vitro assay scientists jobs pay per hour?

As of Sep 13, 2026, the average hourly pay for in vitro assay scientists in the United States is $38.99, according to ZipRecruiter salary data. Most workers in this role earn between $33.89 and $42.55 per hour, depending on experience, location, and employer.

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Infographic showing various In Vitro Assay Scientists job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 92% Full Time, 4% Part Time, and 3% Contract. Highlights an 85% Physical, 3% Hybrid, and 12% Remote job distribution, with an average salary of $81,095 per year, or $39 per hour.

Scientist II, In-Vitro & Nonclinical Assay Development

Frederick, MD • On-site

Tonix Pharmaceuticals
Pharmaceutical and Medicine Manufacturing • 51 - 200 employees
Learn more about Tonix Pharmaceuticalsexternal

Full-time

Posted 22 days ago

Job description

Job Summary

Scientist II will support Tonix Pharmaceuticals' preclinical research programs through the development, optimization, and execution of in vitro and nonclinical assays. The role will contribute to translational research using cell-based assays, DMPK/ADME assays, 3D cell culture and organoid systems, and other nonclinical models to evaluate therapeutic candidates. The scientist will work collaboratively across discovery and development programs and generate high-quality, reproducible data to support program decisions.

Essential Functions

Develop, optimize, and execute in vitro cell-based and biochemical assays to support drug discovery and preclinical development programs.

Perform and support DMPK/ADME assays, including permeability, protein binding, metabolic or CYP-related assays, cytotoxicity, and other screening assays as appropriate.

Develop and evaluate 3D cell culture, spheroid, and organoid-based assay systems for translational and nonclinical studies.

Support the development and execution of nonclinical assays and models for evaluation of therapeutic efficacy, pharmacology, safety, and mechanism of action.

Design experiments, develop and optimize protocols, analyze data, troubleshoot assays, and document results in laboratory records and technical reports.

Maintain mammalian cell culture systems, including established cell lines and primary or specialized cell systems as needed for project-specific assays.

Apply molecular, biochemical, imaging, and viability-based assay methods, including techniques such as RT-PCR, Western blotting, ELISA, luminescence-based assays, microscopy, and related analytical readouts.

Work collaboratively with internal scientists and external partners/CROs to support preclinical and DMPK studies.

Prepare data summaries, presentations, protocols, reports, and other documentation supporting research programs and regulatory or development activities.

Maintain accurate records and perform work in accordance with applicable laboratory, quality, and safety procedures.

Necessary Skills and Abilities

Strong hands-on experience with mammalian cell culture and in vitro assay development.

Experience designing, optimizing, troubleshooting, and interpreting cell-based, biochemical, or translational assays.

Familiarity with DMPK/ADME assay concepts and laboratory methods is preferred.

Experience with 3D culture systems, spheroids, organoids, or other advanced in vitro models is preferred.

Experience supporting nonclinical or preclinical drug development studies.

Proficiency with common molecular and biochemical laboratory techniques and quantitative data analysis.

Strong experimental planning, problem-solving, technical writing, presentation, and communication skills.

Ability to work independently while collaborating effectively in multidisciplinary project teams.

Educational Requirements

  • Ph.D. in Pharmacology, Biochemistry, Biology, Biotechnology, Pharmaceutical Sciences, or a related life sciences discipline; with 2+ years of relevant experience or an M.S. with 4+ years of relevant research experience.

Experience Requirements

Relevant hands-on research experience in pharmaceutical, biotechnology, CRO, government, or academic research environments.

Experience with in vitro pharmacology, assay development, DMPK/ADME, 3D culture/organoid models, or nonclinical research is preferred.

Experience generating reproducible experimental data and communicating results to multidisciplinary teams.

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