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Hourly Upstream Manufacturing Associate Jobs in Encinitas, CA

Abzena Inc.

Manufacturing Lead - Shift B

San Diego, CA · On-site

Lead day-to-day execution of upstream and downstream GMP manufacturing activities. * Coordinate manufacturing floor activities and provide real-time direction to manufacturing associates during ...

Abzena Inc.

Manufacturing Lead - Shift A

San Diego, CA · On-site

Lead day-to-day execution of upstream and downstream GMP manufacturing activities. * Coordinate manufacturing floor activities and provide real-time direction to manufacturing associates during ...

K2 Staffing

General Labor Associate

Carlsbad, CA

$16.50 - $20.75/hr

Summary Our client is a well-established and rapidly growing manufacturing company specializing in ... Competitive hourly compensation based on experience * Opportunity for long-term growth and ...

K2 Staffing, LLC

General Labor Associate

Carlsbad, CA

$20 - $21/hr

Summary Our client is a well-established and rapidly growing manufacturing company specializing in ... Competitive hourly compensation based on experience * Opportunity for long-term growth and ...

GRIFOLS, S.A.

Director of Manufacturing

San Diego, CA · On-site

Specific experience leading upstream and/or downstream bulk manufacturing processes strongly ... an Associate's degree with 6 years of experience, or a Master's degree with 2 years of experience.

Grifols, S.A

Director of Manufacturing

San Diego, CA · On-site

$188 - $250/hr

Specific experience leading upstream and/or downstream bulk manufacturing processes strongly ... an Associate's degree with 6 years of experience, or a Master's degree with 2 years of experience.

Grifols

Director of Manufacturing

San Diego, CA · On-site

Specific experience leading upstream and/or downstream bulk manufacturing processes strongly ... an Associate's degree with 6 years of experience, or a Master's degree with 2 years of experience.

Abzena Inc.

Production Services Associate I

San Diego, CA · On-site

$40K - $60K/yr

The Production Services Associate I will be responsible for supporting both downstream and upstream production in a cGMP manufacturing environment. The Production Services team prepares buffers and ...

Caresoft Inc.

Production Associate

Carlsbad, CA · On-site

$20/hr

Title: Production Associate Duration: 3 Months Location: Carlsbad CA SUMMARY OF POSITION: The ... hourly or matrix testing. Abides by all associated Quality System Regulations (QSRs), manufacturing ...

New

Revvity

Inventory Control Associate I

San Diego, CA

$18 - $22.25/hr

This position will work closely with Manufacturing, Planning, Quality Control, Packaging, material ... Understanding of department tasks upstream and downstream impacts. * Demonstrate a broader ...

Revvity

Inventory Control Associate I

San Diego, CA · On-site

$18 - $22.25/hr

This position will work closely with Manufacturing, Planning, Quality Control, Packaging, material ... Understanding of department tasks upstream and downstream impacts. * Demonstrate a broader ...

Revvity

Inventory Control Associate I

San Diego, CA

$18 - $22.25/hr

This position will work closely with Manufacturing, Planning, Quality Control, Packaging, material ... Understanding of department tasks upstream and downstream impacts. * Demonstrate a broader ...

Midway Staffing

1st Shift Associate 1

San Clemente, CA

$17.50 - $18.50/hr

1st Shift Production Associate Location: San Clemente, CA 92673 Schedule: M-F 6 am to 2:30 pm or ... Committed to following safety, hygiene, and GMP (Good Manufacturing Practice) standards * Bilingual ...

Allegion

Operations Supervisor

Oceanside, CA

Lead a team of approximately 20 to 40 hourly associates to safely produce products and fill ... Utilize lean manufacturing tools to eliminate waste. Lead Rapid Improvement Events (Kaizen) when ...

Allegion

Operations Supervisor

Oceanside, CA

Lead a team of approximately 20 to 40 hourly associates to safely produce products and fill ... Utilize lean manufacturing tools to eliminate waste. Lead Rapid Improvement Events (Kaizen) when ...

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All JobsHourly Upstream Manufacturing Associate JobsHourly Upstream Manufacturing Associate Jobs in Encinitas, CA

Hourly Upstream Manufacturing Associate information

See Encinitas, CA salary details

$13

$22

$35

How much do hourly upstream manufacturing associate jobs pay per hour?

As of Aug 21, 2026, the average hourly pay for hourly upstream manufacturing associate in Encinitas, CA is $22.38, according to ZipRecruiter salary data. Most workers in this role earn between $17.55 and $25.05 per hour, depending on experience, location, and employer.

What is the difference between Hourly Upstream Manufacturing Associate vs Upstream Manufacturing Technician?

AspectHourly Upstream Manufacturing AssociateUpstream Manufacturing Technician
CredentialsHigh school diploma or equivalent; GMP training often requiredHigh school diploma; GMP and technical training
Work EnvironmentManufacturing floor, repetitive tasks, team-basedManufacturing floor, technical troubleshooting, equipment operation
Employer & Industry UsageBiotech and pharmaceutical manufacturingBiotech and pharmaceutical manufacturing
Common Search & ComparisonYesYes

The main difference between an Hourly Upstream Manufacturing Associate and an Upstream Manufacturing Technician lies in their roles and responsibilities. Associates typically perform routine manufacturing tasks under supervision, focusing on production line activities. Technicians often have more technical training, handle troubleshooting, and maintain equipment. Both roles are essential in biotech manufacturing, with similar credentials and work environments, but technicians usually require additional technical skills.

What job categories do people searching Hourly Upstream Manufacturing Associate jobs in Encinitas, CA look for?

The top searched job categories for Hourly Upstream Manufacturing Associate jobs in Encinitas, CA are:

What cities near Encinitas, CA are hiring for Hourly Upstream Manufacturing Associate jobs?

Cities near Encinitas, CA with the most Hourly Upstream Manufacturing Associate job openings:

Hourly Upstream Manufacturing Associate jobs near you
Infographic showing various Hourly Upstream Manufacturing Associate job openings in Encinitas, CA as of June 2026, with employment types broken down into 65% Full Time, 33% Part Time, 1% Temporary, and 1% Nights. Highlights an 96% Physical, 2% Hybrid, and 2% Remote job distribution, with an average salary of $46,552 per year, or $22.4 per hour.

Manufacturing Lead, Operations - Shift B

Abzena Inc.

San Diego, CA • On-site

Full-time

Re-posted 14 days ago

Job description

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing.
Forward-thinking and committed, we find the best solution and use the right technologies to design, develop and manufacture your products to ensure we get vital medicines to patients quickly and safely.
We are dedicated to quality excellence. We are driven to get better treatments to market, efficiently and responsibly by reducing timelines and delivering the highest quality products and services.
We are Abzena. More than a CDMO, we are a responsible and dedicated partner that takes care of your products from concept to patient.
The Lead, Manufacturing Operations is responsible for serving as the subject matter expert and operational lead within GMP manufacturing operations supporting biologics production. This role provides day-to-day directional leadership, coordination, and training for manufacturing personnel involved in upstream and downstream processing activities, including cell culture expansion, bioreactor operations, harvest, purification, filtration, and bulk drug substance manufacturing. The Lead supports batch execution, training, process troubleshooting, documentation review, and operational readiness activities.
Example Plan Shifts/Training Schedule:
- First 2 weeks: 8 hour shifts, M-F
- Next 1-2 months: 10 hour shifts, Mon-Thurs
- After 90 days: 12 hour shifts, Thurs-Sat & Alternating Wednesdays
Schedule is subject to change based on needs.
Responsibilities
  • Provide hands-on training for upstream staff to ensure compliance with training on all activities prior to GMP execution.
  • Adhere to appropriate gowning procedures required for working in Class 10,000 and Class 100,000 cleanrooms.
  • Perform operations in a bio-safety cabinet using aseptic technique and maintain asepsis of all closed container sterile processes.
  • Perform upstream production activities including thawing of cell stocks, inoculum train expansions, cell culture maintenance in bioreactors, depth and sterile filtration, and master cell bank and bulk drug substance fills.
  • Monitor processes and results and troubleshoot issues as they arise to ensure process success.
  • Lead and guide associates through process and workflow improvement initiatives.
  • Lead batch readiness activities such as general planning and coordination, material requests and transfer, and material and equipment staging.
  • Setup, operate and maintain downstream bioprocessing equipment including AKTA ready column chromatography skids, FlexAct automation skids, large scale filtration skids, and analytical instruments such as SoloVPE.
  • Perform downstream production activities including depth filtration, purification by affinity, ion exchange, and hydrophobic interaction chromatography, viral inactivation and filtration, tangential flow filtration, sterile filtration, and bulk drug substance fills.
  • Enforce cleanroom standards for cleanliness and order
  • Direct floor operations for multiple projects simultaneously.
  • Make adjustments as necessary to adhere to production schedules.
  • Cross-train on various tasks including autoclaving of assemblies, formulation of buffers, and Downstream operations to support overall success of the Biologics group.
  • Represent departmental activities as needed, including project teams and task forces.
  • Review GMP records for completeness, accuracy, and compliance on a daily basis in conformance with regulatory requirements.
  • Draft, revise and review manufacturing SOPs, master batch records, specifications, and other applicable cGMP documentation.
  • Adhere to quality standards set by regulations and Abzena policies, procedures, and mission.
  • Operate to the highest ethical and moral standards.
  • Adjust to a flexible work schedule including weekend work, as needed.
  • Perform additional duties as assigned.

Manufacturing Operations Leadership
  • Lead day-to-day execution of upstream and downstream GMP manufacturing activities.
  • Coordinate manufacturing floor activities and provide real-time direction to manufacturing associates during campaign execution.
  • Support media and buffer preparation, inoculum expansion, bioreactor operations, harvest, chromatography, UF/DF, sterile filtration, and bulk drug substance filling.
  • Ensure activities are performed according to approved batch records, SOPs, and production schedules.
  • Provide hands-on training and qualification support for manufacturing personnel.
  • Review GMP documentation for completeness, accuracy, and compliance.
  • Support deviations, CAPAs, change controls, and quality events.
  • Troubleshoot process, equipment, and operational issues.
  • Champion EHS compliance and safe work practices.
  • Partner with QA, QC, MSAT, Engineering, Facilities, Supply Chain, and Program Management.

Team Leadership & Development
  • Train Manufacturing Associates.
  • Provide feedback and review of staff during performance evaluations.
  • Facilitate onboarding and qualification of new employees.
  • Promote a culture of safety, teamwork, accountability, and continuous improvement.
  • Lead daily shift meetings, production reviews, and operational communications.

GMP Compliance & Quality
  • Ensure strict compliance with cGMP regulations, company procedures, and regulatory requirements.
  • Review and verify batch documentation for accuracy and completeness.
  • Support investigations, deviations, CAPAs, change controls, and quality events.
  • Participate in internal audits, client audits, and regulatory inspections.
  • Ensure proper documentation practices and data integrity standards are maintained.

Process Execution & Technical Support
  • Provide technical oversight for upstream and downstream operations.
  • Support process transfers from development to GMP manufacturing.
  • Assist in process validation, engineering runs, and GMP campaign readiness activities.
  • Collaborate with MSAT, Process Development, and Engineering teams to improve process robustness and efficiency.
  • Troubleshoot manufacturing and equipment-related issues.

Safety & Operational Excellence
  • Champion Environmental Health and Safety (EHS) compliance.
  • Ensure safe handling of biological materials, chemicals, and manufacturing equipment.
  • Lead risk assessments and support implementation of corrective actions.
  • Drive Lean Manufacturing and continuous improvement initiatives.
  • Monitor and improve key performance indicators (KPIs) including safety, right-first-time execution, batch success rate, and schedule adherence.

Cross-Functional Collaboration
  • Partner with Quality Assurance, Quality Control, Validation, Facilities, Engineering, Supply Chain, and Program Management teams.
  • Support customer visits and client-facing manufacturing discussions as required.
  • Ensure manufacturing readiness through effective planning and material coordination.

Qualifications
• BA/BS degree that included laboratory work in a chemistry, biology, or related field.
• At least 3 - 4 years of purification experience in a GMP pharmaceutical/biotech environment role.
• Demonstrate knowledge and understanding of cGMPs and how they apply to responsibilities.
• Skilled in aseptic handling, including BSC operations to maintain the integrity of sterile systems.
• Skilled with using single-use technologies
• Strong technical and mechanical aptitude in bioprocessing.
• Knowledge of purification using column chromatography
• Experience leading, training, and coaching peers.
• Computer proficiency
• A proven ability to confidently compute basic arithmetic operations.
Physical Requirements
  • Ability to stand for extended periods of time.
  • Ability to lift 50 pounds in weight.
  • Use arms, hands and fingers to handle, feel or reach.
  • Ability to climb, balance, stoop, kneel, crouch, or crawl.
  • Visual abilities include near and far sight, color, peripheral vision, depth and ability to focus.

$85,000 - $100,000 a year
FLSA: Non-Exempt
Abzena is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, and training.

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