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Homology Modeling Jobs (NOW HIRING)

Givaudan

Cheminformatics Scientist

Cincinnati, OH · On-site

$80K/yr

... homology modeling, protein-protein docking). * Data science and statistical analysis skills, including exploratory data analysis and model validation. * Advanced programming skills in Python or R ...

Latent Labs

Computational Protein Designer

San Francisco, CA · On-site

$24.25 - $29.50/hr

You have experience leveraging generative AI (or other machine learning models) in synthetic biology applications. * You have experience with homology-based and structural bioinformatics, and are ...

Latent Labs

Computational Protein Designer

San Francisco, CA · On-site +1

$24.25 - $29.50/hr

You have experience leveraging generative AI (or other machine learning models) in synthetic biology applications. * You have experience with homology-based and structural bioinformatics, and are ...

EVOZYNE INC

Applied AI Research Fellow

Chicago, IL · On-site

Developing and applying deep learning approaches for remote homology detection * Investigating multi-family VAE models to enable protein design when sequence support is limited or when optimizing ...

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How much do homology modeling jobs pay per hour?

As of Jun 5, 2026, the average hourly pay for homology modeling in the United States is $40.33, according to ZipRecruiter salary data. Most workers in this role earn between $31.25 and $43.51 per hour, depending on experience, location, and employer.

What is homology modeling in bioinformatics?

Homology modeling, also known as comparative modeling, is a computational method used to predict the 3D structure of a protein based on its similarity to one or more proteins with known structures. This technique relies on the assumption that proteins with similar sequences will have similar structures. By aligning the target protein sequence with a related protein (the template), researchers can build a structural model that provides insights into the function and interactions of the target protein. Homology modeling is widely used in drug discovery, protein engineering, and understanding molecular mechanisms when experimental structures are unavailable.

What are the key skills and qualifications needed to thrive as a Homology Modeling Scientist, and why are they important?

To excel as a Homology Modeling Scientist, you need a strong background in structural biology, bioinformatics, and molecular modeling, typically supported by a degree in biochemistry, biophysics, or a related field. Expertise in computational tools like MODELLER, Swiss-Model, and molecular visualization software, as well as familiarity with protein databases, is essential. Analytical thinking, attention to detail, and effective communication are critical soft skills for interpreting results and collaborating with multidisciplinary teams. These competencies ensure accurate protein structure predictions, which are vital for drug discovery and understanding biological mechanisms.

What are some common challenges faced by professionals working in homology modeling, and how can they be addressed?

Professionals in homology modeling often encounter challenges such as limited availability of suitable template structures, inaccuracies in sequence alignments, and difficulties in modeling flexible or poorly conserved regions. Addressing these issues typically involves using multiple templates, carefully refining alignments, and incorporating additional bioinformatics tools to predict loop regions or side-chain conformations. Collaborating with structural biologists and leveraging the latest structural databases can also improve the accuracy and reliability of homology models.
Infographic showing various Homology Modeling job openings in the United States as of May 2026, with employment types broken down into 86% Full Time, 12% Part Time, and 2% Contract. Highlights an 100% Hybrid job distribution, with an average salary of $83,896 per year, or $40.3 per hour.

Cheminformatics Scientist

Givaudan

Cincinnati, OH • On-site

$80K/yr

Other

Medical, Dental, Vision, Retirement

Posted yesterday

Givaudan rating

8.7

Company rating: 8.7 out of 10

Based on 28 frontline employees who took The Breakroom Quiz

13th of 89 rated chemical manufacturers

Job description

Join us and celebrate the beauty of human experience. Create for happier, healthier lives, with love for nature. Together, with our customers, we deliver food innovations, craft inspired fragrances and develop beauty and wellbeing solutions. There's much to learn and many to learn from, with more than 16,000 employees around the world to explore ideas and ambitions with.
In the USA, we develop, market and produce a wide array of solutions from our 25 most innovative sites, based across the country. Stretch your skills, create and get inspiration from passionate colleagues. Every day, your energy, your thirst for knowledge, and your creativity will shape our future, making a positive difference on billions of people. Every essence of you enriches our world. We are Givaudan. Human by nature.

Givaudan Flavors Science & Technology is looking for a Cheminformatics Scientist to join a versatile team advancing flavor ingredient discovery. You will apply cheminformatics, machine learning, and AI to develop novel aroma and taste molecules while collaborating across research teams to build data-driven discovery workflows.

Your Title Cheminformatics Scientist

Your Location Onsite (Givaudan facility)

You Will Report To Flavors Science & Technology Computational Sciences Lead

Responsibilities

  • Design and implement cheminformatics algorithms and workflows to accelerate flavor ingredient discovery across aroma and taste modalities.
  • Develop, validate, and deploy predictive models using QSAR, machine learning, artificial intelligence, and 2D/3D computational approaches for small-molecule analysis and property prediction.
  • Apply statistical, cheminformatics, and machine learning methods to improve hit identification and hit-to-lead processes.
  • Collaborate with chemistry and research teams to integrate AI/ML and cheminformatics into DMTA workflows.
  • Enhance databases and computational pipelines to support data-driven research.
  • Develop computational tools, visualizations, and analytical programs for molecular data analysis.
  • Communicate scientific insights across teams and support collaboration.
  • Provide mentoring and promote best practices in data integrity, reproducibility, and FAIR data principles.

Your Professional Profile Includes

  • PhD or Master's degree in Cheminformatics, Computational Chemistry, Chemistry, or a related discipline.
  • Expertise in structure-based drug design (SBDD), including docking, pharmacophore modeling, virtual screening, and molecular dynamics.
  • 3+ years of experience with ligand-based modeling (QSAR, 2D/3D virtual screening) and protein modeling (e.g., homology modeling, protein-protein docking).
  • Data science and statistical analysis skills, including exploratory data analysis and model validation.
  • Advanced programming skills in Python or R, plus proficiency in an additional language, following coding best practices.
  • Experience with cheminformatics tools (e.g., RDKit, OpenEye) and molecular analysis techniques such as library enumeration, similarity analysis, clustering, and dimensionality reduction.
  • Industry familiarity with SQL/databases, analytics tools (KNIME, Spotfire, Shiny), and NLP/LLMs in scientific contexts; relevant industry experience.

Compensation and Benefits

The established salary range for this position is $80,000-120,000k, depending on individual qualifications and experience. Employees receive medical, dental, and vision coverage, along with a high-matching 401(k) retirement plan.

#LI-Onsite

At Givaudan, you contribute to delightful taste and scent experiences that touch people's lives.
You work within an inspiring teamwork culture - where you can thrive, collaborate and learn from other talented and passionate people across disciplines, regions and divisions.
Every essence of you enriches our world.
Diversity of perspectives fuels innovation and fosters deeper connections with our employees, customers, and partners. At Givaudan, we are dedicated to cultivating an inclusive environment where every individual's voice is valued and has the power to shape our world. Join us in making a difference together.

Employment Type: OTHER

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