High Performance Computing Jobs in Boston, MA (NOW HIRING)

Location Note: This position is permanently based in New York City (Manhattan). While we are advertising in Boston to connect with top-tier technical talent, there is no remote or local hybrid option in Massachusetts. We are seeking elite researchers and engineers eager to advance world-class computational methods for drug discovery right from the heart of NYC’s biotech ecosystem.

The architectural integrity of global investment and technology research relies on the seamless convergence of Systems Engineering and rigorous computational execution. Within this domain, where the synthesis of complex data and high-performance systems is the primary objective, the necessity for first-principles mastery extends beyond the laboratory and into the operational nucleus of the organization.

StaffRight Associates is seeking an elite professional to join the Systems Infrastructure and Networks team at a world-class firm dedicated to the advancement of computational excellence. This role demands a candidate who possesses the intellectual pedigree required to navigate the complex challenges of a research-intensive environment. By bridging specialized technical awareness with proactive problem-solving, the successful candidate will ensure the structural alignment of the firm’s strategic mission with its technical execution.

StaffRight Associates is recruiting for a Systems Engineer (Agents/Clusters/Supercomputers). As a Systems Engineer, you will serve as a vital catalyst within a premier organization. The mission is to decouple systemic friction from analytical progress, allowing the firm’s leadership to maintain a singular focus on the acceleration of Machine Learning, Molecular Dynamics Simulation, and Drug Discovery.

You will be tasked with the sophisticated management of Compute Clusters, Software Environments, and Advanced Infrastructure, transforming abstract organizational needs into formalized, actionable results. This role requires a high degree of technical literacy to effectively support a team leveraging proprietary architectures and sophisticated algorithms to revolutionize Computational Biochemistry and Precision Medicine.

• Orchestrate Systemic Workflows: Formalize and execute complex protocols and high-stakes technical workflows to ensure continuous operational flow for the Infrastructure and Research teams—making Kubernetes-powered agentic workflows, state-of-the-art GPU clusters, and tens of petabytes of storage securely and conveniently available to machine learning researchers.

• Synthesize Complex Data: Conduct ad hoc technical and infrastructure research projects, distilling multifaceted information regarding distributed systems, high-performance RDMA fabrics, and wide-area networks into coherent frameworks that support strategic decision-making.

• Optimize Operational Frameworks: Validate, process, and optimize intricate configurations and technical requirements across Linux clusters (ranging from thousands to tens of thousands of CPU cores) with meticulous attention to detail and systemic accuracy.

• Engineer Multi-Project Solutions: Independently manage a diverse portfolio of concurrent infrastructure initiatives—from optimizing massively parallel custom supercomputers to scripting distributed systems in Python—applying a proactive Goal-Execution-Mapping (GEM) approach to solve emergent bottlenecks.

• Facilitate Elite Communication: Serve as a discreet and articulate interface between the technical committee, internal machine learning researchers, and external stakeholders, maintaining the highest standards of professional integrity.

• Architectural Philosophy: A mindset rooted in efficiency, scalability, and resilience, with the ability to navigate a high-pressure environment without supervision.

• Resourceful Problem-Solving: A proven track record of autonomous execution, demonstrating intellectual curiosity, versatility, and the ability to anticipate systemic performance bottlenecks before they impact the broader workflow.

• Communication Precision: Exceptional interpersonal and communication skills characterized by clarity, discretion, and the ability to interact with elite scientific, machine learning, and business minds.

• Functional Versatility: A generalist systems mindset capable of pivoting fluidly between rigorous Linux systems administration, HPC systems engineering, software development, and advanced network engineering within a high-performance ecosystem.

• Educational Foundation: An advanced degree Masters, PhD is preferred, ideally within a STEM discipline (such as Computer Science, Computer Engineering, or a related field) that provides a foundation for understanding High-Performance Computing (HPC) and Systems Software.

• Domain Expertise: Prior professional engagement within high-performance computing, large-installation systems administration, or advanced technology sectors is highly advantageous, alongside a strong fundamental knowledge of Linux concepts (file systems, networking, and processes).

• Quantitative Literacy: Comfort with the mathematical, algorithmic, and operational rigor inherent in a firm focused on custom supercomputing architecture and high-speed, parallel data processing.

At StaffRight Associates, we operate at the intersection of technical synthesis and structural alignment. We don’t just match resumes to keywords; we map your engineering DNA, your architectural philosophy, and your approach to system resilience to the most sophisticated STEM challenges in the industry.

When you partner with us, you are engaging with an elite team that speaks your language and understands the nuances of high-stakes innovation. We are committed to placing elite talent where their technical contributions drive systemic impact.