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The Genomics AI Program Manager will support a Center-wide Initiative at the New York Genome Center (NYGC) focused on advancing the development and application of artificial intelligence and machine learning approaches to genomic interpretation and human disease. The Initiative brings together NYGC faculty, technologists, computational scientists, and external collaborators to develop and apply large-scale AI models that link genomic sequence to cell-type–specific regulation, disease phenotypes, and biological function.

The mission of the Genomics AI Initiative is to address key bottlenecks in genomic interpretation by integrating high-throughput sequencing, single-cell and spatial multiomics, perturbation and functional genomics, and modern machine learning approaches. This effort is inherently interdisciplinary and collaborative, requiring close coordination across scientific domains, data production and infrastructure, and external collaborative partners.

Position Description

The Program Manager will provide coordination and operational leadership across the full range of activities undertaken by the Genomics AI Initiative. This includes day-to-day management of complex, multi-investigator scientific collaborations; coordination of Consortium-wide activities such as working groups, journal clubs, and symposia; development of scientific and programmatic materials; and support for grant and philanthropic proposal development. The Program Manager will play a central role in enabling collaboration across NYGC leadership, faculty, Genomics AI fellows, external collaborators, and commercial partners by tracking scientific progress, facilitating data access and sharing, supporting computational infrastructure planning, and ensuring alignment across teams. This position will report to the Scientific Director & CEO, or an individual designated by the Scientific Director & CEO, and will work closely with the Genomics AI Initiative participants. This role sits at the intersection of genomics, data science, and program coordination and is well-suited for an incumbent adept at working across scientific disciplines and operational functions.

Key Responsibilities

Genomics AI Program Management

• Manage and coordinate the scientific projects and collaborative activities of the Genomics AI Initiative in alignment with the goals and timelines;

• Support Genomics AI Initiative leadership in organizing and running working groups, steering committee meetings, journal clubs, workshops, and symposia;

• Track scientific objectives, milestones, action items, and dependencies across participating labs and teams, and regularly communicate progress to the Genomics AI Initiative leadership;

• Coordinate the development, review, and dissemination of relevant materials, including presentations, reports, white papers, and scientific summaries;

• Support development of grant applications, philanthropic proposals, and progress reports in collaboration with faculty, Research Administration, and Development;

• Facilitate communication across Genomics AI Initiative participants to ensure alignment, transparency, and efficient collaboration; and

• Organize meetings, prepare agendas and briefing materials, record meeting notes, and track follow-up actions.
  

Data, Infrastructure, and Computational Coordination

• Coordinate data sharing, access, and staging across NYGC teams and external collaborators, in partnership with Informatics, IT, and Data Engineering groups;

• Work with NYGC’s compliance officers and DARB to ensure that data usage is compliant and maintain a list of approved datasets as they relate to AI model development;

• Serve as a liaison between scientific teams and operational groups to support troubleshooting related to data availability, compute usage, workflows, and analysis pipelines; and

• Track dataset access and usage, benchmarking activities, and model development milestones across projects.
  

Genomics AI Initiative Operations and Engagement

• Support onboarding and coordination of Genomics AI Fellows and participating researchers;

• Support development of inter-institutional workflows and agreements, including data access and use, collaboration, etc.;

• Develop and manage annual budgets for Genomics AI Initiative activities and related grant proposals, and monitor expenditures throughout the year to ensure fiscal responsibility and alignment with program priorities; 

• Assist with planning and execution of scientific events and external engagement activities;

• Help maintain strong working relationships among NYGC faculty, fellows, staff, and external partners; and

• Contribute to long-term planning for the growth, sustainability, and evaluation of Genomics AI Initiative.
  

Please note that this job description is not designed to cover or contain a comprehensive listing of activities, duties, or responsibilities required of the employee for this job. Duties, responsibilities, and activities may change.

Position Requirements

• Advanced degree (PhD, MS, or equivalent) in genomics, computational biology, data science, bioinformatics, or a closely related field;

• 2+ years of project or program management experience in a scientific or research environment;

• Demonstrated ability to understand and communicate complex scientific concepts across disciplines;

• Experience working with large datasets, computational workflows, or data-intensive research programs preferred;

• Strong organizational and time management skills, with the ability to manage multiple projects and priorities simultaneously;

• Excellent written and verbal communication skills, including experience preparing scientific or technical materials;

• Ability to work effectively cross-functionally at all levels, including with faculty, trainees, engineers, administrators and institutional partners;

• Comfort operating in a fast-paced, evolving research environment with shifting priorities;

• High degree of Initiative, judgment, and attention to detail; and,

• Ability to work both independently and collaboratively as part of a team.

Don’t meet every single requirement? At NYGC, we are dedicated to building a diverse, inclusive, and authentic workplace, so if you’re excited about this role but your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply anyway. You may be just the right candidate for this or other roles.

Competencies

• Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments.

• Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so.

• Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes Initiative and is solution-oriented; engages in work with passion and curiosity.

Work Flexibility

NYGC has established a flexible work policy to give employees and other staff more ability to balance their work, personal commitments, and commuting challenges. The incumbent is eligible for a flexible work schedule or a hybrid remote work arrangement with supervisory approval.

Salary

The pay range for this position is $110,000 - 130,000 per year; base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off.

About the New York Genome Center

The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the-art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.

Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.

Equal Opportunity

We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization.

The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities. 

FLSA Status – Exempt

This position is not eligible for visa sponsorship

This position is not eligible for relocation assistance