Generative Ai Insurance Jobs in Boston, MA (NOW HIRING)

Principal AI Scientist and Lead
Location: Hybrid- Boston (2 days a week in our Boston Office)
Status: Permanent
Package: Competitive Salary, Remote/Home Working (with one-off allowance), Flexible Working, (2 Days in the office for our Hybrid workers) Development & Opportunity (Personal & Technical), Medical Insurance, Dental Insurance, Vision Insurance, Life Insurance, Long Term & Short-Term Disability Insurance, Generous 401K (matching) Plan, Flexible Spending Account, Health Savings Account, 15 Days' Vacation + Plus Public Holidays + Buy and Sell Scheme.
At Instem, you'll empower pharmaceutical companies, CROs, government agencies, academic institutions, by providing cutting-edge SaaS solutions and consultancy services designed to help researchers make discoveries, and to accelerate and advance their research programs.
You'll work with technology that supports over 50% of global drug discovery and is trusted by leading pharmaceutical, biotech and CRO organisations worldwide.
This position is one of a kind and is the first hire into Instem's AI & Data Sciences department, You will be building production AI on preclinical data: complex agentic systems and predictive models, including models that predict and design in vitro and in vivo studies, carried from prototype through evaluated, observable, hardened production. You will set the technical standard for how the Preclinical group builds, evaluates, and secures AI, and feed that standard into Instem's enterprise AI governance. The position reports to the Chief Scientific Officer and, within twelve to eighteen months, you will buildand lead the team behindyou.
Our Culture & Work Environment.
You'll be part of a friendly, solutions-focused environment within a global business of over 400 people. Here, you'll experience a high-performance culture balanced with genuine flexibility - we trust you to take ownership, deliver meaningful results, and work in a way that suits you.
You'll be encouraged to grow, share your ideas, and make a real impact. We're passionate about creating a place where you can develop your skills, contribute confidently, and succeed in your career.
Why join us as a Principal AI Scientist and Lead/
The role is a brand new role & one that you can shape yourself, alongside a fantastic Chief Scientific Officer!
What You'll Be Doing
Build and Deploy Agentic AI Solutions
• Design and deliver production-ready agentic AI systems that automate complex preclinical workflows using advanced reasoning, orchestration, RAG, and enterprise integrations.
• Develop agent capabilities, tools, APIs, and platform services that support scalable and secure AI adoption.
Develop Predictive & Generative Models
• Build AI models to support study design, prediction, and decision-making across in vitro, in vivo, pathology, and preclinical datasets.
• Apply advanced modelling techniques across toxicity, QSAR, PK/PBPK, omics, and endpoint prediction, ensuring robust scientific validation.
Build the AI Data Estate
• Expand and manage the data assets that underpin Instem's AI capabilities, leveraging owned, customer-governed, public, and partner-sourced data.
Lead AI Evaluation & Observability
• Establish evaluation frameworks, monitoring, and performance controls to ensure AI systems are accurate, reliable, explainable, and production ready.
Partner with Scientific Stakeholders
• Collaborate with Instem scientists, pharmaceutical companies, and CROs to validate outputs, solve scientific challenges, and continuously improve AI solutions.
Ensure Security, Governance & Compliance
• Implement secure, governed, and auditable AI practices, including model lifecycle management, access controls, and compliance with regulatory and GxP requirements
What We're Looking For
• PhD in Machine Learning, Computational Chemistry/Biology, Biomedical Engineering or a related field, or equivalent experience delivering production AI/ML solutions.
• Several years building and deploying AI/ML systems, ideally within preclinical research or drug discovery.
Agentic Engineering
• Proven experience designing and deploying complex agentic AI systems in production environments.
• Strong expertise in LLMs, agent frameworks, RAG architectures, vector databases, context engineering, and enterprise integrations.
• Experienced in building evaluation frameworks, observability, security, governance, and lifecycle management into AI solutions from the outset.
Preclinical Predictive Modelling
• Develops predictive and generative AI models using Python and modern ML frameworks.
• Experienced in applying AI to preclinical and drug discovery challenges, including toxicity prediction, QSAR, PK/PBPK, omics, and endpoint modelling.
• Strong understanding of model validation, uncertainty quantification, regulatory expectations, and scientific applicability.
Scientific & Stakeholder Credibility
• Able to work effectively with scientists, pharmaceutical organisations, and CROs to validate models, interpret results, and communicate scientific rationale.
• Understands both the opportunities and limitations of AI models within defined contexts of use.
Languages & Tooling
• Expert in Python with working knowledge of TypeScript/JavaScript and SQL.
• Exposure to Go, Rust, or other systems languages would be advantageous
What We Offer
We invest in you because you're at the heart of our success. Depending on your location, you'll have access to a range of benefits, including:
• Comprehensive Healthcare (Medical, dental, vision, life, and more)
• Comprehensive wellbeing and support initiatives
• Clear career pathways to support you with getting to the next level
• Pro-rated and immediate vacation days
• Continuous training and development
• Generous retirement plans
Ready to Make a Difference?
Join a team that values your perspective and supports your growth, while helping shape the future of life sciences. Apply now - we'd love to hear from you, and our Talent team will be in touch.
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
Instem stores and processes data using an Applicant Tracking System (ATS). For more information regarding our privacy policy use the following link: https://www.instem.com/privacy/
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