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Genentech Roche Jobs in California (NOW HIRING)

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What is Genentech Roche?

Genentech, a member of the Roche Group, is a leading biotechnology company that researches, develops, and manufactures medicines for serious and life-threatening diseases. Headquartered in South San Francisco, Genentech focuses on areas such as oncology, immunology, neuroscience, and other medical fields. As part of Roche, a global healthcare company based in Switzerland, Genentech combines cutting-edge science with a patient-focused approach to deliver innovative therapies. Their work has led to groundbreaking treatments and a strong commitment to scientific advancement.

What are the key skills and qualifications needed to thrive at Genentech Roche?

To thrive at Genentech Roche, you typically need a strong background in life sciences, biotechnology, or related fields, often supported by relevant degrees or industry experience. Familiarity with research methodologies, laboratory technologies, and data analysis systems such as LIMS or bioinformatics tools is highly valued. Excellent teamwork, adaptability, and strong communication skills help professionals collaborate in a fast-paced, innovation-driven environment. These skills and qualities are crucial for driving scientific discovery, ensuring regulatory compliance, and delivering impactful healthcare solutions.

What is the typical team structure and collaboration style at Genentech Roche?

At Genentech Roche, employees often work in cross-functional teams that bring together experts from research, development, manufacturing, and business operations. Collaboration is highly encouraged through regular meetings, project updates, and knowledge sharing across departments. Team members are expected to contribute their expertise while also learning from others, fostering a culture of innovation and continuous improvement. The company values open communication and often uses collaborative tools and platforms to facilitate efficient teamwork, both in-person and remotely.

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Infographic showing various Genentech Roche job openings in California as of August 2026, with employment types broken down into 82% Full Time, 16% Part Time, and 2% Contract. Highlights an 94% Physical, 3% Hybrid, and 3% Remote job distribution.

Principal Product Leader, Therapeutics Discovery

Genentech

South San Francisco, CA • On-site

Full-time

Re-posted 25 days ago


Genentech rating

8.8

Company rating: 8.8 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

12th of 86 rated pharmaceutical


Job description

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.

The Data and Digital Catalysts (DDC) department within the CS CoE is a diverse, curious and action-driven team at the intersection of science, engineering and computation with ambition to advance our technical excellence. The focus of the team is on bridging the informatics and scientific communities to create a computational and data ecosystem that powers scientific discovery and accelerates decision making. We aim to modernize our ability to acquire, store, link, share, find and analyze data across the organization through scalable and integrated solutions that truly make every data point count. Reporting to the Domain Head for Therapeutics Discovery, this Principal Product Leader will play a key role in defining and executing the strategy for a family of products that are critical for molecule design, making, testing, learning, and/or data lifecyclein drug discovery.

The Therapeutics Discovery (TD) group within DDC is accountable for understanding the "why", defining the "what" and prioritizing the "when" for solutions that enable discovering life-changing therapeutics. Our scientist stakeholders drive the discovery of therapeutic antibodies, small molecules, and new modalities, leveraging best-in-class methodologies spanning antibody engineering, medicinal chemistry, automation, molecule profiling, and AI/ML. The TD group is at the critical intersection of wet and dry labs and data. This role will be accountable for setting and executing on strategy within their product family to support multiple therapeutic modalities in partnership with drug discovery scientists, the domain head and other product family leads within TD and across other domains and REDs.

This is an exciting opportunity to significantly impact and accelerate discovering diverse therapeutics that fundamentally make patients' lives better. You will have the opportunity to work closely with Genentech's top tier scientists and drug discovery experts.

The Opportunity:

As an integral member of this dynamic team, you will be:

  • Define the strategy and product vision for a product family in the Therapeutics Discovery Domain to ensure we enable the highest impact scientific outcomes.

  • Develop deep scientific and problem understanding, articulate the strategic product roadmap, nurture stakeholder relationships, and drive delivery.

  • Boldly advocate for future-facing solutions, anticipate emerging capabilities, understand the Drug Discovery scientific landscape, and influence the Roche/Genentech informatics ecosystem. Integrate all these factors in their roadmaps, budget projections, and collaborations with implementation teams.

  • Contributes to consolidation and deprecation of legacy systems and overall reduction of accumulated technical debt.

  • Establish and cultivate strong internal and external partnerships and relationships with extended collaborators in DDC, CS CoE and beyond.

Who You Are:

In hiring new employees, we look for people who are inspired by our mission and can thrive with the collaborative, thorough, and entrepreneurial spirit of our company culture. Because we know that employees are essential to our success in bringing novel medicines to patients, we are dedicated to remaining an extraordinary place to work and to providing employees with programs, services, and benefits that allow them to bring the best to the organization and to their personal lives.

The ideal candidate will satisfy many of the following requirements:

  • Bachelor's degree plus at least 7 years, or an advanced degree plus at least 2 years proven experience leading delivery of impactful internal solutions that drive significant outcomes. Experience working in a biotechnology setting and understanding scientific drug discovery processes is expected.

  • Leads by example and acts as a mentor and coach for others. Influences without direct authority.

  • Strong in Product Management, such as definition of product vision, strategic thinking, and extended stakeholder management.

  • Hands on domain expertise in the design-make-test-learn aspects of biotechnology. Understanding of how scientific data is collected, managed, analyzed, and used in the discovery process.

  • Experience documenting detailed software requirements, user stories, business processes, and/or software specifications for both custom and Commercial-Off-The-Shelf (COTS) systems.

  • Highly collaborative and demonstrated ability to build positive relationships with internal and external partners. This includes working with globally distributed and cross-functional teams.

  • Outstanding oral and written two-way communication skills. The proven ability to engage with and articulate vision, strategy, and roadmap to diverse audiences, including scientific collaborators, technical teams, and leadership.

Relocation benefits are not available for this posting.

The expected salary range for this position based on the primary location of California $148,600- $276,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.


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About Genentech

Sourced by ZipRecruiter

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

South San Francisco, CA, US

Year founded

1976

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