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Gene Therapy Manufacturing Supervisor Jobs (NOW HIRING)

Astrix Inc

Manufacturing Associate

Cary, NC · On-site

Operate and maintain bioreactors for cell culture and gene therapy manufacturing. * Perform ... downstream purification using AKTA chromatography systems. * Monitor process parameters and ensure ...

RXinsider LTD.

Job Summary The Associate Research Scientist plans, executes and analyzes experiments in cell and gene therapy manufacturing. Collaborates with both internal and external stakeholders in advancing ...

Medical University of South Carolina

Summary The Cell and Gene Therapy Business Coordinator Supervisor provide day-to-day operational ... manufacturers, payers, and institutional stakeholders. Through leadership of the Business ...

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Gene Therapy Manufacturing Supervisor information

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$34.5K

$71.4K

$108K

How much do gene therapy manufacturing supervisor jobs pay per year?

As of Sep 10, 2026, the average yearly pay for gene therapy manufacturing supervisor in the United States is $71,398.00, according to ZipRecruiter salary data. Most workers in this role earn between $60,500.00 and $82,500.00 per year, depending on experience, location, and employer.

What does a gene therapy manufacturing supervisor do?

A Gene Therapy Manufacturing Supervisor oversees the production of gene therapy products in a biomanufacturing environment. This role involves managing daily operations in the manufacturing facility, ensuring compliance with regulatory standards, maintaining product quality, and supervising a team of technicians and operators. They are responsible for coordinating schedules, troubleshooting production issues, and implementing process improvements. The supervisor also ensures all documentation is accurate and that safety protocols are strictly followed.

What are the key skills and qualifications needed to thrive as a gene therapy manufacturing supervisor, and why are they important?

To thrive as a Gene Therapy Manufacturing Supervisor, you need a strong background in biology or biotechnology, experience with GMP (Good Manufacturing Practice) environments, and a relevant degree such as a B.S. or M.S. in a life science field. Familiarity with manufacturing execution systems (MES), process control software, and quality management systems, as well as certifications like Six Sigma or Lean Manufacturing, are typically used in this role. Leadership, problem-solving, and effective communication are vital soft skills for guiding teams and ensuring compliance with rigorous standards. These skills ensure the safe, efficient, and consistent production of gene therapies, which is critical for patient safety and regulatory approval.

What are common challenges faced by gene therapy manufacturing supervisors, and how can they be addressed?

Gene Therapy Manufacturing Supervisors often encounter challenges such as ensuring strict compliance with Good Manufacturing Practices (GMP), managing complex production schedules, and maintaining product quality in a rapidly evolving field. Addressing these challenges requires strong communication skills to coordinate with cross-functional teams, adaptability to implement new technologies and protocols, and a proactive approach to troubleshooting issues on the manufacturing floor. Continuous training and close collaboration with quality assurance and regulatory departments are essential to keep processes efficient and compliant.

What is the difference between Gene Therapy Manufacturing Supervisor vs Manufacturing Technician?

AspectGene Therapy Manufacturing SupervisorManufacturing Technician
CredentialsBachelor's degree in life sciences or related field, GMP training, leadership experienceAssociate's or bachelor's degree, GMP training, technical skills
Work EnvironmentSupervises manufacturing teams in cleanroom settings, oversees processesPerforms hands-on manufacturing tasks in cleanroom or production areas
Employer & IndustryBiotech and pharmaceutical companies specializing in gene therapyBiotech, pharmaceutical, or contract manufacturing organizations

The Gene Therapy Manufacturing Supervisor oversees manufacturing teams and ensures compliance with GMP standards, focusing on process management and team leadership. In contrast, Manufacturing Technicians perform the hands-on tasks required to produce gene therapy products. Both roles are essential in the production process, but the supervisor has a broader responsibility for oversight and coordination.

What are popular job titles related to Gene Therapy Manufacturing Supervisor jobs?

For Gene Therapy Manufacturing Supervisor jobs, the most frequently searched job titles are:

Infographic showing various Gene Therapy Manufacturing Supervisor job openings in the United States as of September 2026, with employment types broken down into 1% As Needed, 76% Full Time, 19% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $71,398 per year, or $34.3 per hour.

Manufacturing Associate

Cary, NC • On-site

Astrix Inc
Recruiting and Staffing Services • 1 - 5K employees
Learn more about Astrix Incexternal

Contractor

Re-posted 4 days ago

Job description

Pay Rate Low: 38 | Pay Rate High: 40
Opportunity to join a cutting edge biotech organization developing innovative gene therapies that enable precise, durable, and scalable treatments for genetic diseases.
We are seeking a motivated Manufacturing Associate with 2+ years of experience in cell and gene therapy production or similar biomanufacturing space. The ideal candidate holds a BS degree and has hands-on expertise within both upstream and downstream processing.
6 month contract (potential of becoming permanent)
Schedule M-F, 8am-4pm
Key Responsibilities:
  • Operate and maintain bioreactors for cell culture and gene therapy manufacturing.
  • Perform downstream purification using AKTA chromatography systems.
  • Monitor process parameters and ensure compliance with SOPs and quality standards.
  • Support batch documentation and data recording.
  • Collaborate with cross-functional teams to optimize manufacturing workflows.
Qualifications:
  • Bachelor's degree in Biotechnology, Biochemistry, or related field.
  • Minimum 2 years' experience in upstream and downstream cell/gene therapy or other related manufacturing.
  • Proficiency with bioreactor operation and AKTA chromatography.
  • Strong attention to detail and adherence to GMP guidelines.
  • Effective communication and teamwork skills.

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