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Full Time Senior Computational Biologist Jobs (NOW HIRING)

Tempus

Senior Computational Biologist I

Chicago, IL · On-site

$115K - $175K/yr

Computational Biology, Genetics, or similar). Alternatively, a PhD in computational biology with a strong record of multi-omic, high-throughput sequencing data analysis * Computational skills using R ...

Tempus

Senior Computational Biologist I

New York, NY · On-site

$115K - $175K/yr

Computational Biology, Genetics, or similar). Alternatively, a PhD in computational biology with a strong record of multi-omic, high-throughput sequencing data analysis * Computational skills using R ...

Tufts University

Computational Biologist

Medford, MA · On-site

$74K - $111K/yr

Reporting to PI Michael Levin and working collaboratively alongside other senior scientists and ... Degree in computational biology, bioinformatics, biostatistics, genomics, systems biology or ...

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How much do full time senior computational biologist jobs pay per year?

As of Sep 11, 2026, the average yearly pay for full time senior computational biologist in the United States is $93,988.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,500.00 and $117,000.00 per year, depending on experience, location, and employer.

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Full Time Senior Computational Biologist jobs near you
Infographic showing various Full Time Senior Computational Biologist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 59% Full Time, 38% Part Time, and 2% Contract. Highlights an 57% Physical, 2% Hybrid, and 41% Remote job distribution, with an average salary of $93,988 per year, or $45.2 per hour.

Sr Computational Biologist (Clinical Biomarkers & Outcomes)

Boston, MA • Hybrid

Foundation Medicine
Biotechnology Research and Development • 1 - 5K employees
Learn more about Foundation Medicineexternal

$145K - $180K/yr

Full-time

Re-posted 4 days ago

Job description

About the Job

The Sr Computational Biologist position sits within the Computational Discovery team and is responsible for building advanced algorithms and technical features that will drive R&D's innovation roadmap. This role leverages multi-modal data, including large scale genomics, real-world clinical outcomes, and imaging datasets, to identify and establish feasibility of novel biomarkers and therapeutic targets. The Sr Computational Biologist contributes as a subject matter expert in cross-functional initiatives to identify opportunities for growth and innovation that can advance FMI's assay and data product capabilities. This position requires a deep understanding of cancer biology and bioinformatics, as well as the ability to communicate complex findings to internal and external stakeholders. 

Key Responsibilities

  • Utilize statistical expertise to explore multimodal data and lead scientific investigations into mechanisms of oncogenesis, prognostic and predictive biomarkers, drug resistance, and disease monitoring.
  • Manage and/or support code bases/repositories and dataset versioning and quality control.
  • Represent Computational Discovery to cross-functional departments and leadership teams to refine product strategy.
  • Collaborate with clinical partners in translational research projects that result in abstracts and publications.
  • Communicate results to both technical and non-technical stakeholders.
  • Other duties as assigned.

Qualifications:

Basic Qualifications:

  • PhD in a life science or mathematical field with a clinical focus and 4+ years of industry or post-doctorate experience within Cancer Biology, Bioinformatics, Biochemistry, or another related life science; OR Master's degree in a life science or mathematical field with clinical focus and 6+ years of industry experience within Cancer Biology, Bioinformatics, Biochemistry, or another related field
  • Proficiency with one or more of the following scientific computing languages: Python, R, Matlab, or Java

Preferred Qualifications:

  • Practical graduate and post-doctoral experience exhibited by first-author publications
  • Subject matter expertise in one of the following areas: cancer genomics, bioinformatics, biostatistics, or machine learning
  • Working knowledge of NGS technology, biomarker development, and real-world clinical outcomes
  • Working knowledge of clinical nomenclature including line of therapy, stage, ECOG, and the patient journey in oncology
  • Experience with computational technologies such as databases (SQL), cloud computing (AWS), and deep learning (AI)
  • Experience managing collaborations with multiple stakeholders
  • Experience mentoring and developing junior scientists
  • Translational research experience and ability to analyze and critically interpret scientific literature
  • Understanding of HIPAA and the importance of patient data privacy
  • Commitment to reflect FMI's values: Integrity, Courage, and Passion 

The expected salary range for this position based on the primary location of Boston, MA is $145,000 - $180,000 per year. The salary range is commensurate with FMI's compensation practice and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for FMI benefits.

#LI-Hybrid

Foundation Medicine, Inc. (FMI) is a global, patient-focused precision medicine company delivering high-quality, transformative diagnostic solutions in cancer and other diseases.

Foundation Medicine is proud to be an Equal Opportunity and Affirmative Action employer and considers all qualified applicants for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity, ancestry, age, or national origin.  Further, qualified applicants will not be discriminated against on the basis of disability or protected veteran status.  We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.  See also FMI's EEO Statement and EEO is the Law and Supplement.  If you have a disability or special need that requires accommodation, please let us know by completing this form.  (EOE/AAP Employer)

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