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Full Time Organic Synthesis Jobs (NOW HIRING)

Associate Oligonucleotide Chemist

Indianapolis, IN · On-site

$23.25 - $30.50/hr

... synthetic organic and/or oligonucleotide chemistry * Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work ...

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Steady work available. Full-time. Minimum Requirements: * At least 1 year of professional ... organic, eco-conscious landscape practices -- no synthetic chemicals.

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Full Time Organic Synthesis information

What are Full Time Organic Synthesis jobs?

Full Time Organic Synthesis jobs involve working as a chemist or researcher specializing in the creation and modification of organic compounds, typically in a laboratory setting. These positions are full-time roles, meaning they require a standard workweek and are not part-time or contract-based. Professionals in this field often work in pharmaceuticals, materials science, or academia, designing and carrying out experiments to develop new molecules or improve existing processes. Tasks may include planning synthetic routes, running reactions, purifying products, and analyzing results using various techniques. A background in chemistry, especially organic chemistry, is essential for these roles.

What are some typical challenges faced by professionals in full-time organic synthesis roles, and how can I prepare for them?

Full-time organic synthesis professionals often encounter challenges such as troubleshooting complex reactions, optimizing yields, and maintaining strict safety protocols when handling hazardous chemicals. These roles require meticulous attention to detail and strong problem-solving skills, as unexpected results and experimental setbacks are common. Collaborating closely with team members is essential, especially when scaling up reactions or sharing analytical data. To prepare, familiarize yourself with modern synthetic techniques and analytical instruments, and stay current with safety best practices.

What are the key skills and qualifications needed to thrive as a Full Time Organic Synthesis Chemist, and why are they important?

To thrive as a Full Time Organic Synthesis Chemist, you need a solid background in organic chemistry, laboratory techniques, and typically a degree in chemistry or a related field. Familiarity with analytical instruments such as NMR, HPLC, GC-MS, and experience with chemical safety protocols are vital. Attention to detail, problem-solving abilities, and strong collaboration skills help set candidates apart. These competencies ensure accurate compound synthesis, safe laboratory practices, and effective teamwork in high-demand research or production environments.

What is the difference between Full Time Organic Synthesis vs Organic Chemist?

AspectFull Time Organic SynthesisOrganic Chemist
CredentialsBachelor's or Master's in Chemistry, Organic Chemistry experienceBachelor's or higher in Chemistry, Organic Chemistry background
Work EnvironmentLaboratories, research facilities, pharmaceutical or chemical companiesResearch labs, industrial settings, academic institutions
Industry UsageCommonly used in pharmaceutical, agrochemical, and specialty chemical industriesUsed across research, development, and manufacturing sectors

Full Time Organic Synthesis roles focus on designing and executing complex organic reactions, often in industrial or research settings. Organic Chemists perform similar tasks but may also include broader research responsibilities. Both roles require strong chemistry credentials and work in laboratory environments, making them closely related but with nuanced differences in scope and application.

More about Full Time Organic Synthesis jobs
What cities are hiring for Full Time Organic Synthesis jobs? Cities with the most Full Time Organic Synthesis job openings:
What are the most commonly searched types of Organic Synthesis jobs? The most popular types of Organic Synthesis jobs are:
What states have the most Full Time Organic Synthesis jobs? States with the most job openings for Full Time Organic Synthesis jobs include:
Infographic showing various Full Time Organic Synthesis job openings in the United States as of June 2026, with employment types broken down into 2% Locum Tenens, 4% Internship, 7% Full Time, 17% Temporary, 67% Contract, and 3% Nights. Highlights an 79% Physical, 2% Hybrid, and 19% Remote job distribution.
Staff Scientist II - Medicinal Chemistry

Staff Scientist II - Medicinal Chemistry

Protagonist Therapeutics

Newark, CA

$135K - $145K/yr

Full-time

Posted 17 days ago


Job description

Staff Scientist II - Medicinal Chemistry

The discovery chemistry team at Protagonist Therapeutics is seeking a highly motivated Staff Scientist II for a full-time small molecule medicinal chemist position. It is a full-time, hands-on bench scientist position, but the individual will have the opportunity to co-lead discovery projects under supervision. The individual will be responsible for design and synthesis of new molecules, solving challenging problems with critical thinking within our multi-disciplinary drug discovery team. The individual will have the opportunity to manage external chemistry resources and provide technical support to ensure high productivity. The individual will have a good track record and be enthusiastic about drug discovery. The individual independently supports multiple research programs and possesses excellent verbal and written communication skills. This individual will report to the Senior Director of Chemistry.
Key responsibilities:

• Propose and synthesize new molecular targets based on structure-activity relationships for compound optimization to advance leads
• Design synthetic routes based on up-to-date literature and hands-on past experience, scale up experience is required
• Solve challenging synthetic problems using various techniques
• Lead and/or assist in writing and revising technical documents including synthetic, analytical protocols and data reports
• Analyze, interpret, summarize, communicate results and data to the team through presentations or other formats in a timely manner
• Provide synthetic chemistry expertise and support cross-functional activities as needed
• Be up to date with scientific literature
• Work with external CROs to manage FTEs and outsourcing activities
• Organize the lab, maintain instruments, reagents, supplies in daily operations and follow EH amp;S rules and regulations
Requirements:

• PhD in Synthetic Organic Chemistry/Medicinal Chemistry with 2-5 yeas of industrial experience in medicinal chemistry
• Proficiency in the following aspects: small molecule target design, organic synthesis and purification, scale up, problem solving, troubleshooting
• Understanding of the biology related to various drug discovery projects
• Proficiency with software such as Microsoft Office, ChemDraw and SciFinder and ability to use computational chemistry software to design molecules
• Experience with electronic notebook, Spotfire and other data management and uploading software is a plus
• Excellent time management skills, organizational skills, high efficiency in the lab, ability to adjust work priorities per project needs, and detailed record keeping of experiments using electronic lab notebooks in a timely manner
• Ability to develop new skillsets and knowledge is highly desirable
• Working independently with limited guidance and multi-tasking are crucial for success
• Ability to collaborate within the team and cross-function in a dynamic and fast-paced environment
• Strong verbal and written communication skills
The base pay range for this position at commencement of employment is expected to be between $135,000 and $145,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.
Protagonist Therapeutics is a discovery through late-stage development biopharmaceutical company. The Company's proprietary peptide technology platform enables de novo discovery of peptide therapeutics. Two novel peptides derived from Protagonist's proprietary discovery platform are at or near commercialization. ICOTYDE™ (icotrokinra) is approved in the U.S. for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age and older who weigh at least 40 kg who are candidates for systemic therapy or phototherapy. ICOTYDE is the first and only targeted oral peptide that precisely blocks the Interleukin-23 receptor (IL-23R) licensed to Janssen Biotech, Inc.,a Johnson amp; Johnson company. ICOTYDE was jointly discovered by Protagonist and Johnson amp; Johnson scientists, with Protagonist having primary responsibility for the development of ICOTYDE through Phase 1, and Johnson amp; Johnson assuming responsibility for further development and commercialization. An NDA for rusfertide, a first-in-class hepcidin mimetic peptide that is being co-developed with Takeda Pharmaceuticals pursuant to a worldwide license and collaboration agreement entered in 2024, is under priority review with the FDA. Protagonist holds an option to co-commercialize rusfertide in the U.S. through a 50/50 profit and loss share structure or can opt-out of this structure. The Company also has a number of preclinical stage drug discovery programs addressing clinically and commercially validated targets including an oral IL-17 peptide antagonist, obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin programs.
More information on Protagonist, its pipeline drug candidates, and clinical studies can be found on the Company's website at https://www.protagonist-inc.com.