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Full Time Method Validation Jobs in Philadelphia, PA

Frontage Laboratories

Associate Scientist

Exton, PA · On-site

  • Medical

  • Dental

  • Life

  • Retirement

... Full-time Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research ... The successful candidate will support bioanalytical method development, validation, and sample ...

Frontage Laboratories

Scientist Senior

Exton, PA · On-site

$88K - $120K/yr

  • Medical

  • Dental

  • Life

  • Retirement

Exton, PA Full-time Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract ... Conduct analytical method development and validation for drug substance and drug product. * Draft ...

Hikma Pharmaceuticals PLC

Microbiologist II

Cherry Hill, NJ · On-site

$56K - $95K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Cherry Hill, NJ Job Type: Full-time Req ID: 11959 About Us: As a developer, manufacturer, and ... Execute test method validation under the direction of supervision. Write/revise standard operating ...

Hikma Pharmaceuticals PLC

Microbiologist II

Cherry Hill, NJ · On-site

$56K - $95K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Cherry Hill, NJ Job Type: Full-time Req ID: 11959 About Us: As a developer, manufacturer, and ... Execute test method validation under the direction of supervision. Write/revise standard operating ...

Hikma Pharmaceuticals PLC

Microbiologist II

Cherry Hill, NJ · On-site

$56K - $95K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Cherry Hill, NJ Job Type: Full-time Req ID: 11961 About Us: As a developer, manufacturer, and ... Execute test method validation under the direction of supervision. Write/revise standard operating ...

Frontage Laboratories

Scientist

Exton, PA · On-site

  • Medical

  • Dental

  • Life

  • Retirement

Manager/Group Leader Full-time Location: Exton, PA Frontage Laboratories Inc. is an award winning ... The scientist's duties include analytical method development/method validation, protocol/report ...

Novocure

Digital Systems Validation Lead

Wayne, PA · Hybrid

$116K - $130K/yr

Digital Systems Validation Lead Chesterbrook, PA | Full-Time | Exempt At Novocure, we are patient ... Establish verification approaches, validation methods, and acceptance criteria, ensuring ...

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All JobsMethod Validation JobsFull Time Method Validation JobsFull Time Method Validation Jobs in Philadelphia, PA

Full Time Method Validation information

See Philadelphia, PA salary details

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How much do full time method validation jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for full time method validation in Philadelphia, PA is $52.47, according to ZipRecruiter salary data. Most workers in this role earn between $39.76 and $63.80 per hour, depending on experience, location, and employer.

What are the most commonly searched types of Method Validation jobs in Philadelphia, PA?

The most popular types of Method Validation jobs in Philadelphia, PA are:

Full Time Method Validation jobs near you
Infographic showing various Full Time Method Validation job openings in Philadelphia, PA as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $109,135 per year, or $52.5 per hour.

Senior Scientist - Method Development-Biomarker LC-MS/MS

Frontage Laboratories

Exton, PA • On-site

$88K - $120K/yr

Full-time

Medical, Dental, Life, Retirement

Re-posted 11 days ago

Job description

Senior Method development scientist-Biomarker LC-MS/MS

Title: Senior method development scientist- Biomarker LC-MS/MS

Location: 700 Pennsylvania Dr. Exton, PA

Reports to: SVP, Central Lab, Biomarker, and Biologics Services

Full-time/on-site


Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.


Position/Job Summary:

The Senior method development scientist supports method development using LC-MS/MS platform for large molecules (biomarkers, proteins, antibodies, ADCs, Oligonucleotides, etc). The senior method development scientist will be a member of the method development team, the responsibility includes serving as subject matter expert when new proposal is received, reviewing the client request and evaluating the feasibility of the project, developing the method after the contract is signed, transferring the developed method to the validation team, and troubleshooting for challenging method.


Roles & Responsibilities:

  • Develop method using LC-MS/MS platform for large molecules (Proteins, antibodies, ADC, Oligonucleotides, Liposomal drugs, biomarkers, etc) quantitation in biological matrices.
  • Facilitate the method transfer from the Method development team with the method validation team.
  • Communicate project timelines, status, and data to Principal Investigator effectively addressing any issues that may arise.
  • Ability to work on multiple projects at the same time.
  • Research literature and external sources and identify new techniques and procedures that strengthen Frontage’s capabilities.
  • Maintain the proper level of regulatory compliance. Ensure that GLP regulations and SOPs are followed in all bioanalytical service activities.
  • Help with training and/or mentoring of junior scientific staff.
  • Set-up, utilize, and maintain complex instrumentation Follow safety precautions.

Education, Experience & Skills Required:

  • Ph.D. or Master’s degree in Analytical Chemistry, Biochemistry, Biology or related scientific discipline.
  • 6-10 years of direct experience of bioanalytical method development for large molecules using LC-MS/MS in the biotech, pharma or CRO industry.
  • Demonstrated experience in mass-spectrometry method development for antibodies including LC-MS intact protein analysis, peptide mapping, conjugate analysis etc.
  • Demonstrated experience in small molecule and protein mass-spectrometry of quantitation of antibody drug-conjugates (ADC), including total Antibody, Conjugated payload, and free payload.
  • Experience with Oligonucleotides and liposomal drug quantitation using LC-MS/MS is a plus.
  • Proven ability to successfully work in a team environment. Excellent oral and written communication skills.
  • Good knowledge and application of GLP with the ability to train technical personnel.
  • Efficient time management.
  • Strong troubleshooting and analytical skills.
  • Detail oriented and meticulous.
  • Ability to work independently under time constraints.


Salary and Benefits:

Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance.


Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.