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Full Time Downstream Process Development Scientist Jobs in Naperville, IL

Senior Process Development Engineer

Chicago, IL · On-site

$107K - $138K/yr

Interpret experimental data and integrate scientific and engineering principles into process development projects. Process Modeling, Data, and Analytics Develop and apply process models for existing ...

Summary Title: R&D Process Development Engineer Location: Chicago, IL  Compensation: Competitive ... scientists and engineers building Numat's current and next-generation products. The work is ...

Summary Title: R&D Process Development Engineer Location: Chicago, IL Compensation: Competitive ... scientists and engineers building Numat's current and next-generation products. The work is ...

Summary Title: R&D Process Development Engineer Location: Chicago, IL Compensation: Competitive ... scientists and engineers building Numat's current and next-generation products. The work is ...

Sci, R&D - Product Dev

Glenview, IL · On-site

$77K - $97K/yr

Independently evaluate, select, and apply standard engineering and scientific techniques, processes, and criteria. Scientist, R&D Product Development - Cream Cheese Are you passionate about Food ...

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Full Time Downstream Process Development Scientist information

See Naperville, IL salary details

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$38

$61

How much do full time downstream process development scientist jobs pay per hour?

As of Aug 9, 2026, the average hourly pay for full time downstream process development scientist in Naperville, IL is $38.61, according to ZipRecruiter salary data. Most workers in this role earn between $28.32 and $46.11 per hour, depending on experience, location, and employer.

What does a full time downstream process development scientist do?

A Full Time Downstream Process Development Scientist is responsible for designing, optimizing, and scaling up processes that purify biological products such as proteins, antibodies, or vaccines after they are produced in cells or microbes. This role involves developing and improving techniques like filtration, chromatography, and centrifugation to ensure high purity and yield of the final product. The scientist also conducts experiments, analyzes data, and collaborates with cross-functional teams to transfer processes from the lab to manufacturing. Their work is critical for producing safe and effective biopharmaceuticals on a large scale.

What is the difference between Full Time Downstream Process Development Scientist vs Downstream Process Engineer?

AspectFull Time Downstream Process Development Scientist
Primary FocusDesigning, optimizing, and developing downstream purification processes for biopharmaceuticals
Required CredentialsBachelor's or Master's in Biotechnology, Biochemistry, or related field; experience in process development
Work EnvironmentLaboratories, R&D settings, collaborative teams in biotech or pharma companies
Typical ResponsibilitiesProcess scale-up, method validation, troubleshooting, documentation

While both roles involve downstream bioprocessing, the Full Time Downstream Process Development Scientist focuses on process development and optimization, whereas the Downstream Process Engineer typically handles process implementation and manufacturing support. The scientist role emphasizes research and development, while the engineer role is more operational. Candidates often hold similar degrees and certifications, but their daily tasks and focus areas differ.

What are some typical challenges faced by a full time downstream process development scientist, and how can they be addressed?

Downstream Process Development Scientists often encounter challenges such as optimizing protein purification processes to achieve high yield and purity, troubleshooting unexpected impurities, and scaling up processes from laboratory to manufacturing scale. These tasks require strong problem-solving skills, meticulous attention to detail, and effective collaboration with upstream teams, analytical scientists, and manufacturing staff. Addressing these challenges involves staying current with new purification technologies, maintaining robust documentation, and participating in cross-functional meetings to ensure seamless process integration and regulatory compliance.

What are the key skills and qualifications needed to thrive as a full time downstream process development scientist, and why are they important?

To thrive as a Full Time Downstream Process Development Scientist, you need a strong background in biochemical engineering, protein purification, and analytical techniques, typically supported by a degree in biochemistry, biotechnology, or a related field. Proficiency with chromatography systems (e.g., HPLC, FPLC), filtration technologies, and knowledge of regulatory and quality systems like GMP is essential. Strong problem-solving abilities, teamwork, and effective communication skills help you collaborate with cross-functional teams and troubleshoot process challenges. These skills are crucial for developing robust purification processes that ensure product quality, regulatory compliance, and efficient production in biopharmaceutical environments.
What are the most commonly searched types of Downstream Process Development Scientist jobs in Naperville, IL? The most popular types of Downstream Process Development Scientist jobs in Naperville, IL are:
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Senior Process Development Engineer

MonoSol

Chicago, IL • On-site

$107K - $138K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 19 days ago


MonoSol rating

7.9

Company rating: 7.9 out of 10

Based on 6 frontline employees who took The Breakroom Quiz


Job description

The Senior Process Development Engineer is responsible for leading complex process research and development activities to enable the successful scale-up, optimization, and industrialization of new and existing products. The role focuses on developing robust manufacturing processes, applying scale-up laws, and building process models for existing or new unit operations. The position combines experimental work, process modeling and simulation, and technical leadership to support business objectives while ensuring compliance with safety, quality, and regulatory standards.
Key Responsibilities
Leadership and Direction
Communicate and execute local action plans aligned with the function's strategy and the broader organization's mission and vision.
Demonstrate strong leadership behaviors, including effective communication, accountability, and proactive problem solving.
Provide technical leadership within process R&D programs and across cross-functional teams.
Process Research and Development
Lead and manage significant elements of the organization's process R&D program, with accountability for process development, scale-up, and technology transfer.
Develop new manufacturing processes for new products, with a strong emphasis on process design, robustness, and scalability.
Identify new process opportunities and conduct innovative experimental and modeling work to translate laboratory concepts into manufacturable solutions.
Process Experiments and Scale-Up
Propose, design, prioritize, and safely execute laboratory, pilot-scale, and scale-up experiments.
Apply fundamental engineering principles and scale-up laws to guide process design and scale-up decisions.
Interpret experimental data and integrate scientific and engineering principles into process development projects.
Process Modeling, Data, and Analytics
Develop and apply process models for existing and new unit operations using appropriate modeling, simulation, and statistical tools.
Use data analysis, statistical methods, and modeling to evaluate hypotheses, predict performance, and optimize processes.
Define and lead execution of data and analytics reporting strategies, ensuring results are communicated in a clear, actionable manner to stakeholders.
Methodologies, Tools, and Continuous Improvement
Identify gaps or shortcomings in current process development methodologies, tools, and workflows.
Propose, implement, and standardize improved process development, modeling, and scale-up practices.
Develop and validate new test methods and process characterization techniques as required.
Communication and Collaboration
Write clear technical reports documenting process development work, experimental results, and modeling outcomes.
Present technical findings to R&D, operations, and management, and communicate effectively across functions and sites.
Engage with external partners, suppliers, customers, and development collaborators as needed to support process development goals.
Innovation and Intellectual Property
Contribute to innovation through the development of novel processes, unit operations, and modeling approaches.
Understand intellectual property related to process and manufacturing technologies and support invention disclosures, patent analyses, and interactions with patent counsel.
Maintain awareness of external technological advances and competitive process technologies.
Project and Portfolio Management
Plan and deliver process development projects or workstreams using appropriate project management methodologies.
Balance technical depth with project execution to ensure milestones are achieved on time and within scope.
Act as a process R&D representative on strategic and cross-functional business teams.
People Development
Provide technical guidance, coaching, and mentoring to junior engineers, scientists, and technicians.
Support capability building within the team through training, knowledge sharing, and best-practice development.
Safety, Quality, and Compliance
Comply with and actively support R&D and laboratory safety programs.
Assume responsibility for assigned lab, pilot, or process areas, including safety, quality, and maintenance standards.
Required Skills and Competencies
Advanced knowledge of process engineering principles, including scale-up laws and unit operations.
Strong background in process modeling, simulation, and data analysis.
Proficiency with analytical, statistical, and scientific software used for modeling and process development.
Ability to manage complexity, optimize work processes, and apply continuous improvement principles.
Strong communication, collaboration, and stakeholder management skills.
Education and Experience
Bachelor's degree in Chemical Engineering, Process Engineering, or a related engineering discipline (Master's or PhD preferred).
Typically 5+ years of experience in process R&D, scale-up, or manufacturing process development.
Demonstrated experience in process modeling, simulation, and data-driven decision making.
Experience mentoring or supervising junior engineers or technicians is preferred.
Additional information
Applicable only to applicants applying to a position in any location with a pay disclosure requirements under state or local law:
The compensation range that is described below is the possible base pay compensation that the company believes in good faith that it will pay for this role at the time of posting based on job grade for the position. Individual compensation within this range is based on many factors such as years of experience etc. so the company might pay more or less than the posted range and it is understood that this range may be modified in the future.
In addition to base compensation, MonoSol provides a yearly incentive compensation bonus, a profit sharing bonus when eligible, a comprehensive benefits package including medical, dental, vision insurances, short term disability, long term disability, accidental death and dismemberment, term life insurance, voluntary term life insurance, transit flexible spending account (if applicable), employee assistance program, identity theft protection, 401k and paid time off (vacation and sick days).
Compensation range - $102,994.61 - $169,225.50
Incentive Compensation Bonus Target - 10% - 15%
Paid time off amount - 15 days
CLOSING
The above statements are intended to describe the general nature and level of the work being performed by employees assigned to this position. This is not intended as an exhaustive list of all responsibilities, duties, and skills required. MonoSol, LLC reserves the right to make changes to the job description whenever necessary.
DISCLAIMER
As part of MonoSol, LLC's employment process, finalist candidates will be required to complete a drug/alcohol test, physical, and background check prior to employment commencing. MonoSol, LLC is an equal opportunity employer. All qualified applicants will be considered without regard to race, national origin, gender, age, disability, sexual orientation, veteran status, or marital status.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws.
For further information, please review the Know Your Rights notice from the Department of Labor.

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