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Fluorescence Jobs in California (NOW HIRING)

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Fluorescence information

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$8

$25

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How much do fluorescence jobs pay per hour?

As of Sep 4, 2026, the average hourly pay for fluorescence in California is $25.79, according to ZipRecruiter salary data. Most workers in this role earn between $14.83 and $30.13 per hour, depending on experience, location, and employer.

What are fluorescence jobs?

Fluorescence jobs typically involve using fluorescence techniques in scientific research or industry settings, such as in biology, chemistry, or medical diagnostics. Professionals in these roles may operate fluorescence microscopes, perform assays, analyze data, and develop new methods for detecting and studying fluorescent signals. These jobs are often found in laboratories, universities, hospitals, and biotech companies, and may require specialized training or education in the relevant scientific field.

What are the key skills and qualifications needed to thrive as a fluorescence microscopist?

To thrive as a Fluorescence Microscopist, you need a strong background in biology, chemistry, or physics, typically with a relevant bachelor's or advanced degree and experience in microscopy techniques. Familiarity with fluorescence microscopes, image analysis software (such as ImageJ or Fiji), and possibly certifications in laboratory safety are essential. Attention to detail, problem-solving ability, and effective communication are crucial soft skills for interpreting data and collaborating with research teams. These skills ensure accurate imaging, reliable data collection, and meaningful scientific discoveries in biological and medical research.

What are some common challenges faced by fluorescence microscopy specialists in a research laboratory setting?

Fluorescence microscopy specialists often navigate challenges such as minimizing photobleaching and phototoxicity during imaging, optimizing sample preparation for clear signal detection, and troubleshooting issues related to instrument calibration and spectral overlap. Collaboration with researchers is key, as specialists may need to tailor protocols for specific experimental needs. Staying updated on evolving imaging technologies and software also helps specialists provide high-quality data and support to their teams.

What is the difference between Fluorescence vs Spectroscopy?

AspectFluorescenceSpectroscopy
Required CredentialsTypically requires a degree in chemistry, biochemistry, or physics; often involves specialized training in fluorescence techniquesRequires similar degrees; often involves training in various spectroscopic methods
Work EnvironmentLaboratories, research facilities, biotech companiesLaboratories, research institutions, industrial settings
Industry UsageUsed for imaging, biomolecular analysis, and chemical detectionUsed for material analysis, chemical composition, and molecular interactions

Fluorescence focuses on measuring emitted light from excited molecules, often for imaging and detection purposes. Spectroscopy encompasses a broader range of techniques analyzing how matter interacts with electromagnetic radiation, including absorption, emission, and scattering. While both require similar educational backgrounds and are used in laboratory settings, fluorescence is more specialized for specific applications like biological imaging, whereas spectroscopy covers a wider array of analytical methods.

What job categories do people searching Fluorescence jobs in California look for?

The top searched job categories for Fluorescence jobs in California are:

Infographic showing various Fluorescence job openings in California as of August 2026, with employment types broken down into 73% Full Time, and 27% Contract. Highlights an 74% In-person, and 26% Remote job distribution, with an average salary of $53,653 per year, or $25.8 per hour.

Staff Research Associate II

University of California San Francisco

San Francisco, CA • On-site

$18.50 - $24.75/hr

Full-time

Re-posted yesterday


University Of California San Francisco rating

7.8

Company rating: 7.8 out of 10

Based on 13 frontline employees who took The Breakroom Quiz

236th of 629 rated colleges and universities


Job description


JOB SUMMARY
The Staff Research Associate II (SRA II) will contribute, as part of the structural biology team, to studies to better understand synuclein and tau prions that accumulated in neurodegenerative diseases. The SRA II will also help to characterize aggregates that are formed in our cellular and animal model systems, to understand how closely their atomic structures resemble those found in human patients, as well as their cellular localization. The employee will also be expected to develop proficiency in transmission electron microscopy and fluorescence microscopy, for structural characterization of protein ultrastructures. The structural biology team is a key part of the overall multidisciplinary Drug Discovery research effort whose research interests span many fields of scientific research and report to the Team Leader. The goal of the team is to identify effective therapeutics against neurodegenerative diseases, including Alzheimer's Disease, Parkinson's disease, progressive supranuclear palsy, chronic traumatic encephalopathy, and multiple system atrophy.
The Institute for Neurodegenerative Diseases (IND) at UCSF is pursuing a cutting-edge blend of basic science and clinical medicine to provide outstanding care to those suffering from neurodegenerative diseases. Founded in 1999, the IND is committed to creating therapeutics that will halt diseases such as Alzheimer's, Parkinson's, Creutzfeldt-Jakob disease and dementia resulting from traumatic brain injuries. The IND is poised to make serious contributions to this struggle at the frontier of neuroscience and medicine. The mission of the Institute for Neurodegenerative Diseases is to discover causes and develop cures for these illnesses with an innovative program of basic research and clinical medicine. The IND's founding director is Nobel Laureate Stanley B. Prusiner, MD.
Responsibilities
DUTIES & ESSENTIAL JOB FUNCTIONS
Identify the functions or tasks that employees in the job perform. The essential functions should state the purpose of the work and the results to be accomplished, rather than how the function is performed. Of the tasks listed, what percentage of time is devoted to each? The more time employees spend on a function, the more likely it is that the function is essential. Generally, include those functions that account for 10% or more of the work, i.e., key items that contribute significantly to the achievement of the job. The functions should add up to 100%.
of time
Essential Function (Yes/No)
Key Responsibilities
(To be completed by Supervisor)
40
YIsolate tau and alpha-synuclein filaments from patient tissues and animal and cellular model systems of interest
25
YFollowing training, perform fluorescence and electron microscopy methods
25
Perform protein expression and purification, and perform biochemical assays.
10
YCommunicate with the supervisor and other IND staff to prioritize projects as further knowledge is gained
0
0
0
0
0
100%
(To update total %, enter the amount of time in whole numbers (without the % symbol - e.g., 15, 20) then highlight the total sum (e.g., 1%) at the bottom of the column and press F9. The total sum should add up to 100%.)
Qualifications
Required Qualifications:
  • BA/BS in Biochemistry, or a related Biological Science field and knowledge of, or experience with, the basic techniques or methods required by the position; and/or an equivalent combination of education and experience.
  • Excellent oral and written communication skills.
  • Knowledge or experience in a research laboratory, including molecular cloning, cell culture and maintaining biological safety protocols.
  • Knowledge of commonly-used concepts, practices, and procedures in protein biochemistry.
  • Computer literacy on both Macintosh and PC, MS-Office suite and basic statistical analysis software.

Required Licenses and/or Certifications:
  • none

Preferred Qualifications:
  • Experience in sample preparation for or performance of transmission electron microscopy
  • Experience in confocal or cryo-confocal fluorescence microscopy
  • Experience in cell sorting
  • Experience in mammalian cell culture

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