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Adme Jobs in California (NOW HIRING)

Aequor

$105K - $144K/yr

Senior Scientist, In Vitro ADME Location: Onsite - Emeryville, CA Duration: 18 months Pay Rate: ***/hr - ***/hr About the Role We are seeking a highly motivated and collaborative Senior Scientist to ...

ALOIS Solutions

Senior Scientist

Emeryville, CA · On-site

$105K - $144K/yr

Conduct ADME screening studies, including but not limited to microsomal stability, hepatocyte stability, permeability, plasma protein binding, and related metabolism assays. * Generate, analyze ...

New

Exelixis

Senior DMPK Director

Alameda, CA · On-site

Lead the Translational IND- and NDA-enabling ADME work; characterize the ADME properties of molecules and collaborate to establish in vitro to in vivo correlations; ensure that all DMPK studies and ...

Exelixis

Senior DMPK Director

Alameda, CA · On-site

Lead the Translational IND- and NDA-enabling ADME work; characterize the ADME properties of molecules and collaborate to establish in vitro to in vivo correlations; ensure that all DMPK studies and ...

Exelixis

Senior DMPK Director

Alameda, CA · On-site

Lead the Translational IND- and NDA-enabling ADME work; characterize the ADME properties of molecules and collaborate to establish in vitro to in vivo correlations; ensure that all DMPK studies and ...

LanceSoft Inc

Scientist I

South San Francisco, CA · On-site

The candidate must have experience in conducting in vitro ADME assays and familiarity with quantitative bioanalysis to support development of novel small molecule therapeutics as detailed below:

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Adme information

What is an adme?

The role of an Adme (Absorption, Distribution, Metabolism, and Excretion) professional typically involves studying how drugs interact with biological systems. They analyze pharmacokinetics and pharmacodynamics to assess drug safety and efficacy. This job is crucial in pharmaceutical research and development, ensuring medications are effective and safe for human use. Adme scientists use laboratory techniques, computational models, and clinical data to predict drug behavior.

What does an adme do?

ADME scientists spend their days designing and conducting experiments to assess how drugs are absorbed, distributed, metabolized, and excreted in biological systems. They analyze data using state-of-the-art lab equipment and software, prepare detailed reports and documentation, and present findings to project teams or regulatory agencies. Collaboration is common, as ADME scientists often work closely with chemists, toxicologists, and clinicians to interpret results and guide drug development strategies. Staying up to date with current regulatory requirements and scientific advancements is also a key part of the job.

What are the key skills and qualifications needed to thrive in the adme position?

To excel as an ADME (Absorption, Distribution, Metabolism, and Excretion) scientist, you typically need a strong background in pharmacology, biochemistry, or related life sciences, often supported by a relevant advanced degree. Familiarity with laboratory instrumentation, bioanalytical methods, and regulatory compliance frameworks such as GLP/GCP guidelines is essential. Attention to detail, strong analytical thinking, and effective teamwork skills help differentiate top candidates. These competencies are vital for generating high-quality data, ensuring regulatory compliance, and driving forward drug development processes.

What are popular job titles related to Adme jobs in California?

For Adme jobs in California, the most frequently searched job titles are:

What job categories do people searching Adme jobs in California look for?

The top searched job categories for Adme jobs in California are:

Adme jobs near you
Infographic showing various Adme job openings in California as of August 2026, with employment types broken down into 95% Full Time, 4% Part Time, and 1% Contract. Highlights an 85% Physical, 6% Hybrid, and 9% Remote job distribution.

Senior Scientist, In Vitro ADME

Aequor

On-site

$105K - $144K/yr

Full-time

Posted 5 days ago

Job description

Job Title: Senior Scientist, In Vitro ADME Location: Onsite - Emeryville, CA Duration: 18 months Pay Rate: ***/hr - ***/hr About the Role We are seeking a highly motivated and collaborative Senior Scientist to support the development and execution of in vitro ADME assays for the evaluation and optimization of potential therapeutic candidates. This onsite role, based in Emeryville, CA, will contribute to drug discovery programs by generating high-quality data to inform compound progression and candidate selection. The ideal candidate will have hands-on experience conducting in vitro ADME assays in a biopharmaceutical, pharmaceutical, or contract research organization setting, with strong technical expertise in LC-MS/MS, enzyme kinetics, cell-based assays, and data interpretation. Key Responsibilities: - Design, develop, and execute in vitro ADME assays to support drug discovery and candidate optimization. - Conduct ADME screening studies, including but not limited to microsomal stability, hepatocyte stability, permeability, plasma protein binding, and related metabolism assays. - Generate, analyze, interpret, and report high-quality data to support project decisions and compound progression. - Collaborate closely with DMPK, biology, chemistry, and project team members to ensure timely delivery of decision-enabling data. - Design and troubleshoot in vitro experiments to address project-specific questions related to compound metabolism, stability, permeability, and protein binding. - Contribute to LC-MS/MS bioanalytical method development, sample analysis, assay optimization, and troubleshooting. - Apply enzyme kinetic and quantitative bioanalytical principles to support assay design and data interpretation. - Prepare experimental protocols, study summaries, technical reports, and presentations for internal stakeholders and project teams. - Maintain accurate documentation in electronic laboratory notebooks and ensure adherence to internal quality and safety standards. - Support implementation and use of laboratory automation platforms, as applicable. Qualifications: - BS or MS in chemistry, biochemistry, pharmacology, pharmaceutical sciences, biology, or a related scientific discipline. - Minimum of 2 years of relevant hands-on in vitro ADME experience in a biopharmaceutical, pharmaceutical, or contract research organization environment. - Strong understanding of DMPK and ADME principles, including assay design, data analysis, and interpretation. - Demonstrated experience designing and executing automated in vitro assays to evaluate and optimize ADME properties of drug candidates. - Hands-on experience with LC-MS/MS-based sample analysis; experience with Sciex instruments is preferred. - Proficiency with data analysis and visualization tools such as Microsoft Excel, GraphPad Prism, Analyst, or similar software. - Experience using electronic laboratory notebooks. - Experience with laboratory automation platforms such as Hamilton, Tecan, or similar systems is preferred. - Strong organizational skills with the ability to manage multiple priorities in a fast-paced, collaborative research environment. - Excellent verbal and written communication skills, with the ability to present scientific findings clearly to cross-functional teams. - Demonstrated ability to work independently while contributing effectively in a team-oriented setting. Note: The successful candidate is expected to maintain a safe laboratory environment and follow all applicable environmental, health, and safety (EHS) policies and procedures. The role requires appropriate handling of chemicals, biological materials, and laboratory instrumentation, including the use of required personal protective equipment (PPE). The candidate should demonstrate a strong commitment to safe laboratory practices. Salary: . Date posted: 08/28/2026

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