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Evidence Director Jobs (NOW HIRING)

This position will have significant interaction with internal stakeholders and will report to the Director of Clinical Evidence. Job Responsibilities * Leads implementation of Clinical Evidence ...

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How much do evidence director jobs pay per year?

As of Jul 1, 2026, the average yearly pay for evidence director in the United States is $123,955.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,000.00 and $137,000.00 per year, depending on experience, location, and employer.
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Associate Director, Real World Evidence (RWE) Science

Associate Director, Real World Evidence (RWE) Science

Ubertal Inc

Waltham, MA • Remote

Contractor

Posted 14 days ago


Job description

Job Title: Associate Director, Real World Evidence (RWE) Science – Phase IV / Post-Approval (Contract)

Location: United States (Remote; Eastern Time business hours preferred)
Duration: 7-Month Contract (Full-Time, 40 hours/week)
Start: Targeting Early March 2026

We are seeking an experienced Associate Director, Real World Evidence (RWE) Science to provide coverage for a Phase IV / post-approval RWE portfolio within a global Medical Affairs environment. This is a senior-level individual contributor role requiring deep epidemiology and real-world evidence expertise, strong methodological leadership, and the ability to independently manage ongoing studies with minimal ramp-up.

This position supports global stakeholders, including Europe, and requires flexibility for early morning meetings aligned to EU collaboration.

Key Responsibilities

  • Lead scientific oversight of Phase IV and post-approval real-world evidence (RWE) and observational studies

  • Provide methodological and technical leadership for study design, feasibility assessments, and evidence planning (EU focus)

  • Oversee vendors/CROs conducting outsourced analyses; review protocols, statistical analysis plans, and outputs to ensure scientific rigor

  • Conduct and/or supervise systematic literature reviews (SLRs) and meta-analyses

  • Contribute to development of RWE plans aligned with regulatory, HTA, and post-approval commitments

  • Support retrospective analyses leveraging real-world data sources (claims, EHR, registries)

  • Guide protocol development for observational studies and pragmatic trials

  • Perform evidence reviews to inform regulatory submissions, reimbursement strategy, and medical strategy

  • Collaborate with Regional Medical Affairs on scientific exchange and external RWE engagement

  • Support development of abstracts, posters, manuscripts, and internal scientific communications

Required Qualifications

  • Advanced degree (MD, PhD, or MS) in Epidemiology, Biostatistics, Public Health, or related field

  • 8–10+ years of progressive experience in epidemiology and real-world evidence

  • Minimum 5 years of Pharma or Biotech industry experience

  • Strong expertise in:

    • Phase IV / post-approval epidemiologic study design

    • Retrospective real-world data (RWD) analyses

    • Observational research methodologies

  • Experience overseeing vendors/CROs and critically evaluating statistical methodologies

  • Proficiency with statistical software (R, SAS, Stata) and strong understanding of claims/EHR data structures

  • Demonstrated ability to work autonomously in a global, matrixed environment

  • Flexibility to support EU collaboration across time zones

Preferred Qualifications

  • Experience supporting regulatory or HTA-facing RWE deliverables

  • Vaccines, infectious disease, or public health epidemiology background

  • Experience with systematic literature reviews and meta-analyses

  • R programming skills, including simulations, power calculations, or Shiny applications

  • Experience with data extraction, cleaning, and standardization for RWD

  • Prior authorship of scientific publications and presentations

  • Experience supporting EU feasibility assessments and RWE expectations

Role Highlights

  • Senior-level RWE leadership without people management responsibilities

  • High-visibility Phase IV and real-world effectiveness portfolio

  • Global collaboration with strong EU engagement

  • Remote flexibility within the United States

Qualified candidates with deep RWE and epidemiology expertise, strong methodological grounding, and Phase IV experience in Pharma/Biotech are encouraged to apply.